The HtrA family of proteases: implications for protein composition and cell fate T Clausen, C Southan, M Ehrmann Molecular cell 10 (3), 443-455, 2002 | 814 | 2002 |
HTRA proteases: regulated proteolysis in protein quality control T Clausen, M Kaiser, R Huber, M Ehrmann Nature reviews Molecular cell biology 12 (3), 152-162, 2011 | 525 | 2011 |
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine T Krojer, M Garrido-Franco, R Huber, M Ehrmann, T Clausen Nature 416 (6879), 455-459, 2002 | 498 | 2002 |
Structural basis for the regulated protease and chaperone function of DegP T Krojer, J Sawa, E Schäfer, HR Saibil, M Ehrmann, T Clausen Nature 453 (7197), 885-890, 2008 | 440 | 2008 |
The role of human HtrA1 in arthritic disease S Grau, PJ Richards, B Kerr, C Hughes, B Caterson, AS Williams, ... Journal of Biological Chemistry 281 (10), 6124-6129, 2006 | 350 | 2006 |
Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease C Wilken, K Kitzing, R Kurzbauer, M Ehrmann, T Clausen Cell 117 (4), 483-494, 2004 | 334 | 2004 |
Molecular machines for protein degradation M Groll, M Bochtler, H Brandstetter, T Clausen, R Huber Chembiochem 6 (2), 222-256, 2005 | 288 | 2005 |
Proteolysis as a regulatory mechanism M Ehrmann, T Clausen Annu. Rev. Genet. 38 (1), 709-724, 2004 | 284 | 2004 |
Moyamoya disease: diagnosis and interventions M Ihara, Y Yamamoto, Y Hattori, W Liu, H Kobayashi, H Ishiyama, ... The Lancet Neurology 21 (8), 747-758, 2022 | 251 | 2022 |
Implications of the serine protease HtrA1 in amyloid precursor protein processing S Grau, A Baldi, R Bussani, X Tian, R Stefanescu, M Przybylski, ... Proceedings of the National Academy of Sciences 102 (17), 6021-6026, 2005 | 247 | 2005 |
Arginine phosphorylation marks proteins for degradation by a Clp protease DB Trentini, MJ Suskiewicz, A Heuck, R Kurzbauer, L Deszcz, K Mechtler, ... Nature 539 (7627), 48-53, 2016 | 217 | 2016 |
Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function E Karaca, S Weitzer, D Pehlivan, H Shiraishi, T Gogakos, T Hanada, ... Cell 157 (3), 636-650, 2014 | 214 | 2014 |
Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities M Breuss, JIT Heng, K Poirier, G Tian, XH Jaglin, Z Qu, A Braun, T Gstrein, ... Cell reports 2 (6), 1554-1562, 2012 | 208 | 2012 |
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR J Fuhrmann, A Schmidt, S Spiess, A Lehner, K Turgay, K Mechtler, ... Science 324 (5932), 1323-1327, 2009 | 203 | 2009 |
Crystal Structure of the Pyridoxal-5′-phosphate Dependent Cystathionine β-lyase fromEscherichia coliat 1.83 Å T Clausen, R Huber, B Laber, HD Pohlenz, A Messerschmidt Journal of molecular biology 262 (2), 202-224, 1996 | 196 | 1996 |
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress M Stephani, L Picchianti, A Gajic, R Beveridge, E Skarwan, ... elife 9, e58396, 2020 | 195 | 2020 |
Protein quality control in the bacterial periplasm M Merdanovic, T Clausen, M Kaiser, R Huber, M Ehrmann Annual review of microbiology 65 (1), 149-168, 2011 | 195 | 2011 |
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly JT Kaiser, T Clausen, GP Bourenkow, HD Bartunik, S Steinbacher, ... Journal of molecular biology 297 (2), 451-464, 2000 | 189 | 2000 |
A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors F Malvezzi, G Litos, A Schleiffer, A Heuck, K Mechtler, T Clausen, ... The EMBO journal 32 (3), 409-423, 2013 | 180 | 2013 |
Stress-Induced GSK3 Regulates the Redox Stress Response by Phosphorylating Glucose-6-Phosphate Dehydrogenase in Arabidopsis S Dal Santo, H Stampfl, J Krasensky, S Kempa, Y Gibon, E Petutschnig, ... The Plant Cell 24 (8), 3380-3392, 2012 | 174 | 2012 |