Fluoxetine: a case history of its discovery and preclinical development L Perez-Caballero, S Torres-Sanchez, L Bravo, JA Mico, E Berrocoso Expert opinion on drug discovery 9 (5), 567-578, 2014 | 207 | 2014 |
Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression I Gárate, B García-Bueno, JLM Madrigal, L Bravo, E Berrocoso, JR Caso, ... Journal of neuroinflammation 8, 1-14, 2011 | 207 | 2011 |
Discovery and development of tramadol for the treatment of pain L Bravo, JA Mico, E Berrocoso Expert opinion on drug discovery 12 (12), 1281-1291, 2017 | 196 | 2017 |
Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression L Bravo, JA Mico, R Rey-Brea, B Pérez-Nievas, JC Leza, E Berrocoso Anesthesiology 117 (3), 613-625, 2012 | 125 | 2012 |
Chemogenetic silencing of the locus coeruleus–basolateral amygdala pathway abolishes pain-induced anxiety and enhanced aversive learning in rats M Llorca-Torralba, I Suárez-Pereira, L Bravo, C Camarena-Delgado, ... Biological Psychiatry 85 (12), 1021-1035, 2019 | 104 | 2019 |
The role of the locus coeruleus in pain and associated stress-related disorders I Suárez-Pereira, M Llorca-Torralba, L Bravo, C Camarena-Delgado, ... Biological psychiatry 91 (9), 786-797, 2022 | 88 | 2022 |
Monoamines as drug targets in chronic pain: focusing on neuropathic pain L Bravo, M Llorca-Torralba, E Berrocoso, JA Micó Frontiers in Neuroscience 13, 1268, 2019 | 74 | 2019 |
Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: the role of the locus coeruleus L Bravo, C Alba-Delgado, S Torres-Sanchez, JA Mico, FL Neto, ... PAIN® 154 (10), 2014-2023, 2013 | 64 | 2013 |
Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons M Llorca-Torralba, C Camarena-Delgado, I Suárez-Pereira, L Bravo, ... Brain 145 (1), 154-167, 2022 | 62 | 2022 |
Pain exacerbates chronic mild stress-induced changes in noradrenergic transmission in rats L Bravo, S Torres-Sanchez, C Alba-Delgado, JA Mico, E Berrocoso European Neuropsychopharmacology 24 (6), 996-1003, 2014 | 60 | 2014 |
Pain in neuropsychiatry: Insights from animal models L Bravo, M Llorca-Torralba, I Suárez-Pereira, E Berrocoso Neuroscience & Biobehavioral Reviews 115, 96-115, 2020 | 35 | 2020 |
Opioid activity in the locus coeruleus is modulated by chronic neuropathic pain M Llorca-Torralba, F Pilar-Cuéllar, L Bravo, C Bruzos-Cidon, M Torrecilla, ... Molecular Neurobiology 56, 4135-4150, 2019 | 31 | 2019 |
Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats T Chaumette, E Chapuy, E Berrocoso, M Llorca‐Torralba, L Bravo, ... European Journal of Pain 22 (1), 127-141, 2018 | 25 | 2018 |
Effect of DSP4 and desipramine in the sensorial and affective component of neuropathic pain in rats L Bravo, JA Mico, R Rey-Brea, C Camarena-Delgado, E Berrocoso Progress in Neuro-Psychopharmacology and Biological Psychiatry 70, 57-67, 2016 | 23 | 2016 |
Sexual differences in locus coeruleus neurons and related behavior in C57BL/6J mice P Mariscal, L Bravo, M Llorca-Torralba, J Razquin, C Miguelez, ... Biology of sex Differences 14 (1), 64, 2023 | 14 | 2023 |
Nerve injury induces transient locus coeruleus activation over time: role of the locus coeruleus–dorsal reticular nucleus pathway C Camarena-Delgado, M Llorca-Torralba, I Suárez-Pereira, L Bravo, ... Pain 163 (5), 943-954, 2022 | 14 | 2022 |
Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour I García-Domínguez, I Suárez-Pereira, M Santiago, EM Pérez-Villegas, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 104, 110030, 2021 | 14 | 2021 |
The absence of caspase-8 in the dopaminergic system leads to mild autism-like behavior I Suárez-Pereira, I García-Domínguez, L Bravo, M Santiago, ... Frontiers in Cell and Developmental Biology 10, 839715, 2022 | 10 | 2022 |
Animal models in psychiatry: conceptualization and preclinical models of depression L Bravo, E Berrocoso, JA Mico European Journal of Psychiatry 23 (Supl), 111-122, 2009 | 9 | 2009 |
Antidepressant drugs and pain BL Cobo-Realpe, C Alba-Delgado, L Bravo, JA Mico, E Berrocoso Effects of Antidepressants 1, 144-162, 2012 | 5 | 2012 |