A microRNA DNA methylation signature for human cancer metastasis A Lujambio, GA Calin, A Villanueva, S Ropero, M Sánchez-Céspedes, ... Proceedings of the National Academy of Sciences 105 (36), 13556-13561, 2008 | 1361 | 2008 |
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth WJ Faller, TJ Jackson, JRP Knight, RA Ridgway, T Jamieson, SA Karim, ... Nature 517 (7535), 497-500, 2015 | 315 | 2015 |
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis CR Lindsay, S Lawn, AD Campbell, WJ Faller, F Rambow, RL Mort, ... Nature communications 2 (1), 555, 2011 | 192 | 2011 |
HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia TS Rai, JJ Cole, DM Nelson, D Dikovskaya, WJ Faller, MG Vizioli, ... Genes & development 28 (24), 2712-2725, 2014 | 164 | 2014 |
Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal AJ Muinonen-Martin, O Susanto, Q Zhang, E Smethurst, WJ Faller, ... PLoS biology 12 (10), e1001966, 2014 | 146 | 2014 |
Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes A Li, JP Morton, YF Ma, SA Karim, Y Zhou, WJ Faller, EF Woodham, ... Gastroenterology 146 (5), 1386-1396. e17, 2014 | 122 | 2014 |
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells DJ Huels, L Bruens, MC Hodder, P Cammareri, AD Campbell, ... Nature communications 9 (1), 1132, 2018 | 77 | 2018 |
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ... Cancer discovery 11 (5), 1228-1247, 2021 | 75 | 2021 |
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis JDG Leach, N Vlahov, P Tsantoulis, RA Ridgway, DJ Flanagan, K Gilroy, ... Nature communications 12 (1), 3464, 2021 | 64 | 2021 |
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation Y Ma, A Li, WJ Faller, S Libertini, F Fiorito, DA Gillespie, OJ Sansom, ... Development 140 (10), 2203-2211, 2013 | 62 | 2013 |
Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis WJ Faller, M Rafferty, S Hegarty, G Gremel, D Ryan, MF Fraga, M Esteller, ... Melanoma research 20 (5), 392-400, 2010 | 62 | 2010 |
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer S Prekovic, K Schuurman, I Mayayo-Peralta, AG Manjón, M Buijs, S Yavuz, ... Nature Communications 12 (1), 4360, 2021 | 54 | 2021 |
Oncogene-dependent sloppiness in mRNA translation J Champagne, A Pataskar, N Blommaert, R Nagel, D Wernaart, ... Molecular cell 81 (22), 4709-4721. e9, 2021 | 40 | 2021 |
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis N Rohwer, S Jumpertz, M Erdem, A Egners, KT Warzecha, A Fragoulis, ... Oncogene 38 (28), 5670-5685, 2019 | 37 | 2019 |
Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression J Kohli, C Ge, E Fitsiou, M Doepner, SM Brandenburg, WJ Faller, ... Nature Communications 13 (1), 7923, 2022 | 29 | 2022 |
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis D Ryan, M Rafferty, S Hegarty, P O’Leary, W Faller, G Gremel, ... Pigment cell & melanoma research 23 (4), 542-553, 2010 | 28 | 2010 |
Early life antibiotics influence in vivo and in vitro mouse intestinal epithelium maturation and functioning TM Garcia, M van Roest, JLM Vermeulen, S Meisner, WL Smit, J Silva, ... Cellular and molecular gastroenterology and hepatology 12 (3), 943-981, 2021 | 27 | 2021 |
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis N Kumar, M Srivillibhuthur, S Joshi, KD Walton, A Zhou, WJ Faller, ... Development 143 (20), 3711-3722, 2016 | 27 | 2016 |
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K JRP Knight, N Vlahov, DM Gay, RA Ridgway, WJ Faller, C Proud, ... Elife 10, e69729, 2021 | 22 | 2021 |
Identifying ribosome heterogeneity using ribosome profiling F Alkan, OG Wilkins, S Hernández-Pérez, S Ramalho, J Silva, J Ule, ... Nucleic acids research 50 (16), e95-e95, 2022 | 20 | 2022 |