Gel-forming mucins form distinct morphologic structures in airways LS Ostedgaard, TO Moninger, JD McMenimen, NM Sawin, CP Parker, ... Proceedings of the National Academy of Sciences 114 (26), 6842-6847, 2017 | 173 | 2017 |
Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense X Li, XX Tang, LG Vargas Buonfiglio, AP Comellas, IM Thornell, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (7 …, 2016 | 53 | 2016 |
Regulators of Slc4 bicarbonate transporter activity IM Thornell, MO Bevensee Frontiers in physiology 6, 166, 2015 | 49 | 2015 |
Inflammatory cytokines TNF-α and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators T Rehman, PH Karp, P Tan, BJ Goodell, AA Pezzulo, AL Thurman, ... The Journal of clinical investigation 131 (16), 2021 | 45 | 2021 |
Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus AL Cooney, BK Singh, LM Loza, IM Thornell, CE Hippee, LS Powers, ... Nucleic acids research 46 (18), 9591-9600, 2018 | 43 | 2018 |
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin T Rehman, IM Thornell, AA Pezzulo, AL Thurman, GS Romano Ibarra, ... American Journal of Physiology-Cell Physiology 319 (2), C331-C344, 2020 | 38 | 2020 |
Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation KS Evonuk, RE Doyle, CE Moseley, IM Thornell, K Adler, AM Bingaman, ... Science advances 6 (2), eaax5936, 2020 | 38 | 2020 |
CFTR-rich ionocytes mediate chloride absorption across airway epithelia L Lei, S Traore, GSR Ibarra, PH Karp, T Rehman, DK Meyerholz, J Zabner, ... The Journal of clinical investigation 133 (20), 2023 | 36 | 2023 |
A novel AAV-mediated gene delivery system corrects CFTR function in pigs AL Cooney, IM Thornell, BK Singh, VS Shah, DA Stoltz, PB McCray Jr, ... American journal of respiratory cell and molecular biology 61 (6), 747-754, 2019 | 36 | 2019 |
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling S Mao, AS Shah, TO Moninger, LS Ostedgaard, L Lu, XX Tang, ... Proceedings of the National Academy of Sciences 115 (6), 1370-1375, 2018 | 36 | 2018 |
Sodium–bicarbonate cotransporter NBCn1 in the kidney medullary thick ascending limb cell line is upregulated under acidic conditions and enhances ammonium transport S Lee, HJ Lee, HS Yang, IM Thornell, MO Bevensee, I Choi Experimental physiology 95 (9), 926-937, 2010 | 30 | 2010 |
PIP2 hydrolysis stimulates the electrogenic Na+–bicarbonate cotransporter NBCe1‐B and ‐C variants expressed in Xenopus laevis oocytes IM Thornell, J Wu, X Liu, MO Bevensee The Journal of physiology 590 (23), 5993-6011, 2012 | 26 | 2012 |
Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model K Zarei, MR Stroik, ND Gansemer, AL Thurman, LS Ostedgaard, SE Ernst, ... Laboratory investigation 100 (11), 1388-1399, 2020 | 20 | 2020 |
V-type ATPase mediates airway surface liquid acidification in pig small airway epithelial cells X Li, R Villacreses, IM Thornell, J Noriega, S Mather, CM Brommel, L Lu, ... American journal of respiratory cell and molecular biology 65 (2), 146-156, 2021 | 18 | 2021 |
Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing IM Thornell, X Li, XX Tang, CM Brommel, PH Karp, MJ Welsh, J Zabner Physiological reports 6 (2), e13569, 2018 | 17 | 2018 |
A single-cell atlas of large and small airways at birth in a porcine model of cystic fibrosis AL Thurman, X Li, R Villacreses, W Yu, H Gong, SE Mather, ... American journal of respiratory cell and molecular biology 66 (6), 612-622, 2022 | 16 | 2022 |
Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH IM Thornell, T Rehman, AA Pezzulo, MJ Welsh The Journal of physiology 598 (19), 4307-4320, 2020 | 16 | 2020 |
Lung function of primary cooks using LPG or biomass and the effect of particulate matter on airway epithelial barrier integrity EM Stapleton, AK Puliyakote, N Metwali, M Jeronimo, IM Thornell, ... Environmental research 189, 109888, 2020 | 14 | 2020 |
Phosphatidylinositol 4,5‐bisphosphate degradation inhibits the Na+/bicarbonate cotransporter NBCe1‐B and ‐C variants expressed in Xenopus oocytes IM Thornell, MO Bevensee The Journal of physiology 593 (3), 541-558, 2015 | 14 | 2015 |
The IP3 receptor‐binding protein IRBIT reduces phosphatidylinositol 4,5‐bisphosphate (PIP2) stimulation of Na/bicarbonate cotransporter NBCe1 variants … IM Thornell, J Wu, MO Bevensee The FASEB Journal 24, 815.6-815.6, 2010 | 14 | 2010 |