Targeted temperature management at 33 C versus 36 C after cardiac arrest N Nielsen, J Wetterslev, T Cronberg, D Erlinge, Y Gasche, C Hassager, ... New England journal of medicine 369 (23), 2197-2206, 2013 | 3269 | 2013 |
Codeine intoxication associated with ultrarapid CYP2D6 metabolism Y Gasche, Y Daali, M Fathi, A Chiappe, S Cottini, P Dayer, J Desmeules New England Journal of Medicine 351 (27), 2827-2831, 2004 | 847 | 2004 |
Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia JM Gidday, YG Gasche, JC Copin, AR Shah, RS Perez, SD Shapiro, ... American Journal of Physiology-Heart and Circulatory Physiology 289 (2 …, 2005 | 644 | 2005 |
Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood—brain barrier dysfunction Y Gasche, M Fujimura, Y Morita-Fujimura, JC Copin, M Kawase, ... Journal of Cerebral Blood Flow & Metabolism 19 (9), 1020-1028, 1999 | 581 | 1999 |
Matrix metalloproteinase inhibition prevents oxidative stress-associated blood–brain barrier disruption after transient focal cerebral ischemia Y Gasche, JC Copin, T Sugawara, M Fujimura, PH Chan Journal of Cerebral Blood Flow & Metabolism 21 (12), 1393-1400, 2001 | 498 | 2001 |
Early appearance of activated matrix metalloproteinase-9 and blood–brain barrier disruption in mice after focal cerebral ischemia and reperfusion M Fujimura, Y Gasche, Y Morita-Fujimura, J Massengale, M Kawase, ... Brain research 842 (1), 92-100, 1999 | 492 | 1999 |
Standardized EEG interpretation accurately predicts prognosis after cardiac arrest E Westhall, AO Rossetti, AF van Rootselaar, T Wesenberg Kjaer, J Horn, ... Neurology 86 (16), 1482-1490, 2016 | 388 | 2016 |
Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase … T Sugawara, N Noshita, A Lewen, Y Gasche, M Ferrand-Drake, ... Journal of Neuroscience 22 (1), 209-217, 2002 | 342 | 2002 |
Neuron-specific enolase as a predictor of death or poor neurological outcome after out-of-hospital cardiac arrest and targeted temperature management at 33 C and 36 C P Stammet, O Collignon, C Hassager, MP Wise, J Hovdenes, A Åneman, ... Journal of the American College of Cardiology 65 (19), 2104-2114, 2015 | 337 | 2015 |
Effects of global ischemia duration on neuronal, astroglial, oligodendroglial, and microglial reactions in the vulnerable hippocampal CA1 subregion in rats T Sugawara, A Lewén, N Noshita, Y Gasche, PH Chan Journal of neurotrauma 19 (1), 85-98, 2002 | 264 | 2002 |
Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis T Berney, Y Gasche, J Robert, A Jenny, N Mensi, G Grau, B Vermeulen, ... Pancreas 18 (4), 371-377, 1999 | 231 | 1999 |
Neurologic function and health-related quality of life in patients following targeted temperature management at 33 C vs 36 C after out-of-hospital cardiac arrest: a randomized … T Cronberg, G Lilja, J Horn, J Kjaergaard, MP Wise, T Pellis, J Hovdenes, ... JAMA neurology 72 (6), 634-641, 2015 | 225 | 2015 |
Target temperature management after out-of-hospital cardiac arrest—a randomized, parallel-group, assessor-blinded clinical trial—rationale and design N Nielsen, J Wetterslev, N Al-Subaie, B Andersson, J Bro-Jeppesen, ... American heart journal 163 (4), 541-548, 2012 | 193 | 2012 |
Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption? GW Kim, Y Gasche, S Grzeschik, JC Copin, CM Maier, PH Chan Journal of Neuroscience 23 (25), 8733-8742, 2003 | 179 | 2003 |
Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency M Kawase, K Murakami, M Fujimura, Y Morita-Fujimura, Y Gasche, ... Stroke 30 (9), 1962-1968, 1999 | 171 | 1999 |
Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain Y Gasche, PM Soccal, M Kanemitsu, JC Copin Front Biosci 11 (5), 1289-1301, 2006 | 159 | 2006 |
Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma Y Morita-Fujimura, M Fujimura, Y Gasche, JC Copin, PH Chan Journal of Cerebral Blood Flow & Metabolism 20 (1), 130-138, 2000 | 147 | 2000 |
Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release T Sugawara, A Lewén, Y Gasche, F Yu, PH Chan The FASEB Journal 16 (14), 1997-1999, 2002 | 146 | 2002 |
Overexpression of copper/zinc superoxide dismutase does not prevent neonatal lethality in mutant mice that lack manganese superoxide dismutase JC Copin, Y Gasche, PH Chan Free Radical Biology and Medicine 28 (10), 1571-1576, 2000 | 140 | 2000 |
Survival in patients without acute ST elevation after cardiac arrest and association with early coronary angiography: a post hoc analysis from the TTM trial J Dankiewicz, N Nielsen, M Annborn, T Cronberg, D Erlinge, Y Gasche, ... Intensive care medicine 41, 856-864, 2015 | 118 | 2015 |