UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells JH Kim, A Sharma, SS Dhar, SH Lee, B Gu, CH Chan, HK Lin, MG Lee Cancer research 74 (6), 1705-1717, 2014 | 257 | 2014 |
Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4 SS Dhar, SH Lee, PY Kan, P Voigt, L Ma, X Shi, D Reinberg, MG Lee Genes & development 26 (24), 2749-2762, 2012 | 211 | 2012 |
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling KW Wagner, H Alam, SS Dhar, U Giri, N Li, Y Wei, D Giri, T Cascone, ... The Journal of clinical investigation 123 (12), 5231-5246, 2013 | 199 | 2013 |
KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ... Cancer cell 37 (4), 599-617. e7, 2020 | 192 | 2020 |
Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons SS Dhar, S Ongwijitwat, MTT Wong-Riley Journal of Biological Chemistry 283 (6), 3120-3129, 2008 | 190 | 2008 |
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes NA Li, Y Li, J Lv, X Zheng, H Wen, H Shen, G Zhu, TY Chen, SS Dhar, ... Molecular cell 63 (3), 470-484, 2016 | 142 | 2016 |
MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ... Molecular cell 70 (5), 825-841. e6, 2018 | 141 | 2018 |
JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis N Li, SS Dhar, TY Chen, PY Kan, Y Wei, JH Kim, CH Chan, HK Lin, ... Cancer research 76 (4), 831-843, 2016 | 132 | 2016 |
Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA … SS Dhar, MTT Wong-Riley Journal of Neuroscience 29 (2), 483-492, 2009 | 105 | 2009 |
A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness SH Lee, TY Chen, SS Dhar, B Gu, K Chen, YZ Kim, W Li, MG Lee Nucleic acids research 44 (22), 10603-10618, 2016 | 78 | 2016 |
An essential role for UTX in resolution and activation of bivalent promoters SS Dhar, SH Lee, K Chen, G Zhu, WK Oh, K Allton, O Gafni, YZ Kim, ... Nucleic acids research 44 (8), 3659-3674, 2016 | 78 | 2016 |
Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells SS Dhar, H Alam, N Li, KW Wagner, J Chung, YW Ahn, MG Lee Journal of Biological Chemistry 289 (11), 7483-7496, 2014 | 78 | 2014 |
HP1γ promotes lung adenocarcinoma by downregulating the transcription-repressive regulators NCOR2 and ZBTB7A H Alam, N Li, SS Dhar, SJ Wu, J Lv, K Chen, ER Flores, L Baseler, ... Cancer research 78 (14), 3834-3848, 2018 | 75 | 2018 |
Chemotherapy-induced late transgenerational effects in mice LL Kujjo, EA Chang, RJG Pereira, S Dhar, B Marrero-Rosado, ... PloS one 6 (3), e17877, 2011 | 59 | 2011 |
Nuclear respiratory factor 1 co‐regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy … SS Dhar, HL Liang, MTT Wong‐Riley Journal of neurochemistry 108 (6), 1595-1606, 2009 | 54 | 2009 |
Chromosome conformation capture of all 13 genomic Loci in the transcriptional regulation of the multisubunit bigenomic cytochrome C oxidase in neurons SS Dhar, S Ongwijitwat, MTT Wong-Riley Journal of Biological Chemistry 284 (28), 18644-18650, 2009 | 51 | 2009 |
Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors SS Dhar, MG Lee Oncotarget 12 (13), 1296, 2021 | 46 | 2021 |
Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4 Y Liu, S Qin, TY Chen, M Lei, SS Dhar, JC Ho, A Dong, P Loppnau, Y Li, ... Nature communications 10 (1), 36, 2019 | 39 | 2019 |
p38 mitogen‐activated protein kinase and calcium channels mediate signaling in depolarization‐induced activation of peroxisome proliferator‐activated receptor gamma coactivator … HL Liang, SS Dhar, MTT Wong‐Riley Journal of neuroscience research 88 (3), 640-649, 2010 | 34 | 2010 |
Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c … SS Dhar, HL Liang, MTT Wong-Riley Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (10), 1604-1613, 2009 | 33 | 2009 |