Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs A Minden, A Lin, FX Claret, A Abo, M Karin Cell 81 (7), 1147-1157, 1995 | 2001 | 1995 |
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2 A Lin, A Minden, H Martinetto, FX Claret, C Lange-Carter, F Mercurio, ... Science 268 (5208), 286-290, 1995 | 1037 | 1995 |
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor J Arias, AS Alberts, P Brindle, FX Claret, T Smeal, M Karin, J Feramisco, ... Nature 370 (6486), 226-229, 1994 | 1012 | 1994 |
Trastuzumab: updated mechanisms of action and resistance in breast cancer T Vu, FX Claret Frontiers in oncology 2, 62, 2012 | 804 | 2012 |
Induction of c‐fos expression through JNK‐mediated TCF/Elk‐1 phosphorylation. M Cavigelli, F Dolfi, FX Claret, M Karin The EMBO journal 14 (23), 5957-5964, 1995 | 711 | 1995 |
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors FX Claret, M Hibi, S Dhut, T Toda, M Karin Nature 383 (6599), 453-457, 1996 | 598 | 1996 |
Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death H Le-Niculescu, E Bonfoco, Y Kasuya, FX Claret, DR Green, M Karin Molecular and cellular biology 19 (1), 751-763, 1999 | 584 | 1999 |
Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells A Mansouri, LD Ridgway, AL Korapati, Q Zhang, L Tian, Y Wang, ... Journal of Biological Chemistry 278 (21), 19245-19256, 2003 | 500 | 2003 |
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury T Herdegen, FX Claret, T Kallunki, A Martin-Villalba, C Winter, T Hunter, ... Journal of Neuroscience 18 (14), 5124-5135, 1998 | 434 | 1998 |
A nucleosome‐dependent static loop potentiates estrogen‐regulated transcription from the Xenopus vitellogenin B1 promoter in vitro. C Schild, FX Claret, W Wahli, AP Wolffe The EMBO journal 12 (2), 423-433, 1993 | 276 | 1993 |
AP-1 transcription factors as regulators of immune responses in cancer V Atsaves, V Leventaki, GZ Rassidakis, FX Claret Cancers 11 (7), 1037, 2019 | 262 | 2019 |
Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase–positive anaplastic large cell lymphoma F Vega, LJ Medeiros, V Leventaki, C Atwell, JH Cho-Vega, L Tian, ... Cancer research 66 (13), 6589-6597, 2006 | 239 | 2006 |
Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells X Fang, S Yu, RC Bast, S Liu, HJ Xu, SX Hu, R LaPushin, FX Claret, ... Journal of Biological Chemistry 279 (10), 9653-9661, 2004 | 233 | 2004 |
The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition XF Le, FX Claret, A Lammayot, L Tian, D Deshpande, R LaPushin, ... Journal of Biological Chemistry 278 (26), 23441-23450, 2003 | 225 | 2003 |
JAB1/CSN5: a new player in cell cycle control and cancer TJ Shackleford, FX Claret Cell division 5, 1-14, 2010 | 177 | 2010 |
Mutual regulation of microRNAs and DNA methylation in human cancers S Wang, W Wu, FX Claret Epigenetics 12 (3), 187-197, 2017 | 169 | 2017 |
Expression of Phosphorylated p27Kip1 Protein and Jun Activation Domain-Binding Protein 1 in Human Pituitary Tumors M Korbonits, HS Chahal, G Kaltsas, S Jordan, Y Urmanova, Z Khalimova, ... The Journal of Clinical Endocrinology & Metabolism 87 (6), 2635-2643, 2002 | 148 | 2002 |
Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo-and radio-sensitivity in nasopharyngeal carcinoma Y Pan, F Zhou, R Zhang, FX Claret PloS one 8 (1), e54565, 2013 | 144 | 2013 |
2-Acetylaminofluorene Up-regulates Rat mdr1bExpression through generating reactive oxygen species that activate NF-κB pathway L Deng, YC Lin-Lee, FX Claret, MT Kuo Journal of Biological Chemistry 276 (1), 413-420, 2001 | 138 | 2001 |
Negative transcriptional regulation by nuclear receptors. F Saatcioglu, FX Claret, M Karin Seminars in cancer biology 5 (5), 347-359, 1994 | 137 | 1994 |