| Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs) Y Lei, X Guo, Y Liu, Y Cao, Y Deng, X Chen, CHK Cheng, IB Dawid, ... Proceedings of the National Academy of Sciences 109 (43), 17484-17489, 2012 | 329 | 2012 |
| DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells X Zhang, J Su, M Jeong, M Ko, Y Huang, HJ Park, A Guzman, Y Lei, ... Nature genetics 48 (9), 1014-1023, 2016 | 278 | 2016 |
| DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ... Genome biology 18, 1-11, 2017 | 243 | 2017 |
| Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang, Y Zhou, W Li, ... Nature communications 8 (1), 16026, 2017 | 231 | 2017 |
| Loss of Dnmt3a immortalizes hematopoietic stem cells in vivo M Jeong, HJ Park, H Celik, EL Ostrander, JM Reyes, A Guzman, ... Cell reports 23 (1), 1-10, 2018 | 228 | 2018 |
| Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors J Hu, Y Lei, WK Wong, S Liu, KC Lee, X He, W You, R Zhou, JT Guo, ... Nucleic acids research 42 (7), 4375-4390, 2014 | 189 | 2014 |
| Homeobox oncogene activation by pan-cancer DNA hypermethylation J Su, YH Huang, X Cui, X Wang, X Zhang, Y Lei, J Xu, X Lin, K Chen, J Lv, ... Genome biology 19, 1-12, 2018 | 121 | 2018 |
| DNA methylation and de-methylation using hybrid site-targeting proteins Y Lei, YH Huang, MA Goodell Genome Biology 19, 1-12, 2018 | 70 | 2018 |
| A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish Y Liu, D Luo, Y Lei, W Hu, H Zhao, CHK Cheng Methods 69 (1), 58-66, 2014 | 55 | 2014 |
| Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos Y Lei, X Guo, Y Deng, Y Chen, H Zhao Cell & Bioscience 3, 1-10, 2013 | 52 | 2013 |
| Mutagenesis at specific genomic loci of amphioxus Branchiostoma belcheri using TALEN method G Li, J Feng, Y Lei, J Wang, H Wang, LK Shang, DT Liu, H Zhao, Y Zhu, ... Journal of genetics and genomics= Yi chuan xue bao 41 (4), 215, 2014 | 38 | 2014 |
| Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos Z Liu, TTK Cheng, Z Shi, Z Liu, Y Lei, C Wang, W Shi, X Chen, X Qi, D Cai, ... Cell & bioscience 6, 1-13, 2016 | 18 | 2016 |
| Zebrafish Nanos interacts with and regulates the phosphorylation of Mylz2 Y Xu, H Wang, J Zhou, Y Lei, Y Zhou, Q Yang, D Ye, W Li, F Deng Biochimie 92 (12), 1812-1817, 2010 | 7 | 2010 |
| A robust pipeline for ranking carrier frequencies of autosomal recessive and X-linked Mendelian disorders W Zhu, C Wang, N Mullapudi, Y Cao, L Li, IFM Lo, SKW Tsui, X Chen, ... NPJ Genomic Medicine 7 (1), 72, 2022 | 6 | 2022 |
| Decoding hereditary spastic paraplegia pathogenicity through transcriptomic profiling NJ Ho, X Chen, Y Lei, S Gu Zoological Research 44 (3), 650, 2023 | 4 | 2023 |
| Cloning, characterization and expression of zvep, a novel vitelline envelope‐specific gene in the zebrafish ovary Y Xu, Y Lei, Q Liu, Y Liu, S Liu, H Cheng, F Deng Molecular Reproduction and Development: Incorporating Gamete Research 76 (6 …, 2009 | 3 | 2009 |
| Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun. 2017; 8: 16026 Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang | 2 | |
| Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma JX Wang, L Zhang, PW Zhang, LW Yuan, J Jiang, XH Cheng, W Zhu, ... Biology Direct 20 (1), 1, 2025 | | 2025 |
| Boanmycin induces apoptosis and overcomes venetoclax resistance in acute myeloid leukemia JX Wang, PW Zhang, LW Yuan, J Jiang, XH Cheng, JH Li, MQ Tang, ... Oncologie 26 (5), 743-752, 2024 | | 2024 |
| A robust pipeline for ranking carrier frequencies of autosomal recessive and X-linked Mendelian disorders W Zhu, C Wang, N Mullapudi, Y Cao, L Li, FM Lo, S Tsui, X Chen, Y Lei, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 311-311, 2024 | | 2024 |
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