Christophe LMJ Verlinde

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Katkıda bulunan yazarlar

Wesley Van VoorhisProfessor of Medicine, Univ of WAuw.edu üzerinde doğrulanmış e-posta adresine sahip
Ethan A MerrittResearch Associate Professor, Biochemistry, University of Washingtonu.washington.edu üzerinde doğrulanmış e-posta adresine sahip
Michael H. GelbProfessor of Chemistry, University of Washingtonuw.edu üzerinde doğrulanmış e-posta adresine sahip
Eric T. LarsonHotSpot Therapeutics, Rheos Medicines, HarkerBio, Boehringer Ingelheim, U of WA, MT State Universityhotspotthera.com üzerinde doğrulanmış e-posta adresine sahip
Kayode K. OjoUniversity of Washingtonu.washington.edu üzerinde doğrulanmış e-posta adresine sahip
Cho Yeow KohNational University of Singaporenus.edu.sg üzerinde doğrulanmış e-posta adresine sahip
Fred OpperdoesEmeritus professor, Université catholique de Louvainuclouvain.be üzerinde doğrulanmış e-posta adresine sahip
Wenlin HuangUniversity of Washingtonuw.edu üzerinde doğrulanmış e-posta adresine sahip
Krzysztof PalczewskiUCI ophthalmologyuci.edu üzerinde doğrulanmış e-posta adresine sahip
Joseph R LuftHauptman-Woodwardhwi.buffalo.edu üzerinde doğrulanmış e-posta adresine sahip
Oliver HuckeAssociate Director, Boehringer Ingelheim Pharmaboehringer-ingelheim.com üzerinde doğrulanmış e-posta adresine sahip
Ximena Barros-AlvarezStanford Universitystanford.edu üzerinde doğrulanmış e-posta adresine sahip
Galina LepeshevaResearch Professorvanderbilt.edu üzerinde doğrulanmış e-posta adresine sahip
Richard T EastmanNovartis Institutes for BioMedical Research- Global Healthnovartis.com üzerinde doğrulanmış e-posta adresine sahip
B Gayani K PereraDepartment of Chemistry, University of Washingtonuw.edu üzerinde doğrulanmış e-posta adresine sahip
A Clinton WhiteUniversity of Texas Medical Branchutmb.edu üzerinde doğrulanmış e-posta adresine sahip
Robert FarissChief, Biological Imaging Core, National Eye Institute-NIHnei.nih.gov üzerinde doğrulanmış e-posta adresine sahip
Arthur Van AerschotEmeritus Full professor medicinal chemistry, KU Leuvenrega.kuleuven.be üzerinde doğrulanmış e-posta adresine sahip
Andre Lieberuw.edu üzerinde doğrulanmış e-posta adresine sahip
Bosch JürgenCase Western Reserve University & Johns Hopkins Universitycase.edu üzerinde doğrulanmış e-posta adresine sahip

Takip et

Christophe LMJ Verlinde

Associate professor of Biochemistry, University of Washington, Seattle

u.washington.edu üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa

structure-based drug design fragment based drug discovery neglected diseases x-ray crystallography antivirals


Başlık Alıntılara göre sırala Yıla göre sırala Başlığa göre sırala	Alıntı yapanlar Alıntı yapanlar	Yıl
Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase FS Buckner, CL Verlinde, AC La Flamme, WC Van Voorhis Antimicrobial agents and chemotherapy 40 (11), 2592-2597, 1996	624	1996
Macromolecular Crystallography and Medicine WGJ Hol, CLMJ Verlinde International Tables for Crystallography F, 10-43, 2006	395*	2006
Structure-based drug design: progress, results and challenges CLMJ Verlinde, WGJ Hol Structure 2 (7), 577-587, 1994	379	1994
Genomic-scale prioritization of drug targets: the TDR Targets database F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ... Nature reviews Drug discovery 7 (11), 900-907, 2008	373	2008
High-affinity pentavalent ligands of Escherichia coli heat-labile enterotoxin by modular structure-based design E Fan, Z Zhang, WE Minke, Z Hou, CLMJ Verlinde, WGJ Hol Journal of the American Chemical Society 122 (11), 2663-2664, 2000	366	2000
Glycolysis as a target for the design of new anti-trypanosome drugs CLMJ Verlinde, V Hannaert, C Blonski, M Willson, JJ Périé, ... Drug Resistance Updates 4 (1), 50-65, 2001	328	2001
Missense mutations in the regulatory domain of PKCγ: a new mechanism for dominant nonepisodic cerebellar ataxia DH Chen, Z Brkanac, LMJC Verlinde, XJ Tan, L Bylenok, D Nochlin, ... The American Journal of Human Genetics 72 (4), 839-849, 2003	303	2003
Five members of a novel Ca2+-binding protein (CABP) subfamily with similarity to calmodulin F Haeseleer, I Sokal, CLMJ Verlinde, H Erdjument-Bromage, P Tempst, ... Journal of Biological Chemistry 275 (2), 1247-1260, 2000	287	2000
Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors KK Ojo, ET Larson, KR Keyloun, LJ Castaneda, AE DeRocher, ... Nature structural & molecular biology 17 (5), 602-607, 2010	199	2010
Rational modification of a candidate cancer drug for use against Chagas disease JM Kraus, CLMJ Verlinde, M Karimi, GI Lepesheva, MH Gelb, FS Buckner Journal of medicinal chemistry 52 (6), 1639-1647, 2009	188	2009
AB5 toxins: structures and inhibitor design E Fan, EA Merritt, CLMJ Verlinde, WGJ Hol Current opinion in structural biology 10 (6), 680-686, 2000	179	2000
Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase AM Aronov, S Suresh, FS Buckner, WC Van Voorhis, CLMJ Verlinde, ... Proceedings of the National Academy of Sciences 96 (8), 4273-4278, 1999	176	1999
Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin Z Zhang, EA Merritt, M Ahn, C Roach, Z Hou, CLMJ Verlinde, WGJ Hol, ... Journal of the American Chemical Society 124 (44), 12991-12998, 2002	165	2002
Adenosine Analogues as Selective Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosomatidae via Structure-Based Drug Design JC Bressi, CLMJ Verlinde, AM Aronov, ML Shaw, SS Shin, LN Nguyen, ... Journal of medicinal chemistry 44 (13), 2080-2093, 2001	156	2001
Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii RC Murphy, KK Ojo, ET Larson, A Castellanos-Gonzalez, BGK Perera, ... ACS medicinal chemistry letters 1 (7), 331-335, 2010	154*	2010
Alternatively spliced isoforms of the human constitutive androstane receptor SS Auerbach, R Ramsden, MA Stoner, C Verlinde, C Hassett, ... Nucleic acids research 31 (12), 3194-3207, 2003	154	2003
Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors X Qiu, CLMJ Verlinde, S Zhang, MP Schmitt, RK Holmes, WGJ Hol Structure 3 (1), 87-100, 1995	154	1995
Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery JM Kraus, HB Tatipaka, SA McGuffin, NK Chennamaneni, M Karimi, J Arif, ... Journal of medicinal chemistry 53 (10), 3887-3898, 2010	146	2010
Structure-based exploration of the ganglioside GM1 binding sites of Escherichia coli heat-labile enterotoxin and cholera toxin for the discovery of receptor antagonists WE Minke, C Roach, WGJ Hol, CLMJ Verlinde Biochemistry 38 (18), 5684-5692, 1999	142	1999
Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the … H Kim, IK Feil, CLMJ Verlinde, PH Petra, WGJ Hol Biochemistry 34 (46), 14975-14986, 1995	142	1995

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