Takip et
Anne M. Brown
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Molecular dynamics simulations of amyloid β-peptide (1-42): tetramer formation and membrane interactions
AM Brown, DR Bevan
Biophysical journal 111 (5), 937-949, 2016
992016
A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation
L Kang, G He, AK Sharp, X Wang, AM Brown, P Michalak, ...
Cell 184 (17), 4392-4400. e4, 2021
892021
Comparing atomistic molecular mechanics force fields for a difficult target: a case study on the Alzheimer’s amyloid β-peptide
SR Gerben, JA Lemkul, AM Brown, DR Bevan
Journal of Biomolecular Structure and Dynamics 32 (11), 1817-1832, 2014
882014
Purine biosynthesis in archaea: variations on a theme
AM Brown, SL Hoopes, RH White, CA Sarisky
Biology direct 6, 1-21, 2011
512011
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2
JJ Liu, X Zou, T Gotoh, AM Brown, L Jiang, EL Wisdom, JK Kim, ...
Science Signaling 11 (556), eaau0715, 2018
452018
Transforming sphingosine kinase 1 inhibitors into dual and sphingosine kinase 2 selective inhibitors: design, synthesis, and in vivo activity
ES Childress, Y Kharel, AM Brown, DR Bevan, KR Lynch, WL Santos
Journal of medicinal chemistry 60 (9), 3933-3957, 2017
452017
Simulations of monomeric amyloid β-peptide (1–40) with varying solution conditions and oxidation state of Met35: Implications for aggregation
AM Brown, JA Lemkul, N Schaum, DR Bevan
Archives of biochemistry and biophysics 545, 44-52, 2014
442014
Protein kinases in Toxoplasma gondii
RY Gaji, AK Sharp, AM Brown
International journal for parasitology 51 (6), 415-429, 2021
352021
Structure of the sensory domain of McpX from Sinorhizobium meliloti, the first known bacterial chemotactic sensor for quaternary ammonium compounds
M Shrestha, KK Compton, JM Mancl, BA Webb, AM Brown, BE Scharf, ...
Biochemical Journal 475 (24), 3949-3962, 2018
332018
Development of a structured undergraduate research experience: Framework and implications
AM Brown, SN Lewis, DR Bevan
Biochemistry and Molecular Biology Education 44 (5), 463-474, 2016
322016
Structure–activity relationship studies and molecular modeling of naphthalene-based sphingosine kinase 2 inhibitors
MD Congdon, Y Kharel, AM Brown, SN Lewis, DR Bevan, KR Lynch, ...
ACS Medicinal Chemistry Letters 7 (3), 229-234, 2016
312016
Insights into stabilizing forces in amyloid fibrils of differing sizes from polarizable molecular dynamics simulations
DS Davidson, AM Brown, JA Lemkul
Journal of Molecular Biology 430 (20), 3819-3834, 2018
292018
Inositol trisphosphate kinase and diphosphoinositol pentakisphosphate kinase enzymes constitute the inositol pyrophosphate synthesis pathway in plants
O Adepoju, SP Williams, B Craige, CA Cridland, AK Sharpe, AM Brown, ...
Biorxiv, 724914, 2019
272019
Discovery of a small side cavity in sphingosine kinase 2 that enhances inhibitor potency and selectivity
CD Sibley, EA Morris, Y Kharel, AM Brown, T Huang, DR Bevan, ...
Journal of medicinal chemistry 63 (3), 1178-1198, 2020
242020
HIV-1 Env gp41 transmembrane domain dynamics are modulated by lipid, water, and ion interactions
LR Hollingsworth, JA Lemkul, DR Bevan, AM Brown
Biophysical journal 115 (1), 84-94, 2018
232018
Influence of sequence and lipid type on membrane perturbation by human and rat amyloid β-peptide (1–42)
AM Brown, DR Bevan
Archives of Biochemistry and Biophysics 614, 1-13, 2017
222017
Development and feasibility of an online brief emotion regulation training (BERT) program for emerging adults
AJ Gatto, TJ Elliott, JS Briganti, MJ Stamper, ND Porter, AM Brown, ...
Frontiers in public health 10, 858370, 2022
152022
Rosmarinic acid potently detoxifies amylin amyloid and ameliorates diabetic pathology in a transgenic rat model of type 2 diabetes
L Wu, P Velander, AM Brown, Y Wang, D Liu, DR Bevan, S Zhang, B Xu
ACS Pharmacology & Translational Science 4 (4), 1322-1337, 2021
152021
Lipophilic tail modifications of 2-(hydroxymethyl) pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors
H Li, CD Sibley, Y Kharel, T Huang, AM Brown, LG Wonilowicz, DR Bevan, ...
Bioorganic & medicinal chemistry 30, 115941, 2021
152021
NMR model of the entire membrane-interacting region of the HIV-1 fusion protein and its perturbation of membrane morphology
A Piai, Q Fu, AK Sharp, B Bighi, AM Brown, JJ Chou
Journal of the American Chemical Society 143 (17), 6609-6615, 2021
142021
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