Takip et
Rudi Fasan
Rudi Fasan
Robert Welch Professor of Chemistry, Dept of Chemistry & Biochemistry, University of Texas at Dallas
utdallas.edu üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Tuning P450 enzymes as oxidation catalysts
R Fasan
Acs Catalysis 2 (4), 647-666, 2012
4042012
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
R Fasan, MM Chen, NC Crook, FH Arnold
Angewandte Chemie International Edition 46 (44), 8414-8418, 2007
3262007
Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions
OF Brandenberg, R Fasan, FH Arnold
Current opinion in biotechnology 47, 102-111, 2017
3212017
Highly diastereoselective and enantioselective olefin cyclopropanation using engineered myoglobin‐based catalysts
M Bordeaux, V Tyagi, R Fasan
Angewandte Chemie 127 (6), 1764-1768, 2015
3162015
Molecular basis of RNA recognition by the human alternative splicing factor Fox‐1
SD Auweter, R Fasan, L Reymond, JG Underwood, DL Black, S Pitsch, ...
The EMBO journal 25 (1), 163-173, 2006
3122006
Evolutionary history of a specialized P450 propane monooxygenase
R Fasan, YT Meharenna, CD Snow, TL Poulos, FH Arnold
Journal of molecular biology 383 (5), 1069-1080, 2008
2662008
Using a b-hairpin to mimic an a-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, JW Vrijbloed, D Obrecht, ...
Angewandte Chemie-International Edition 43 (16), 2109-2112, 2004
2472004
Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
K Zhang, BM Shafer, MD Demars, HA Stern, R Fasan
Journal of the American Chemical Society 134 (45), 18695-18704, 2012
2162012
P450-Catalyzed Intramolecular sp3 C–H Amination with Arylsulfonyl Azide Substrates
R Singh, M Bordeaux, R Fasan
ACS catalysis 4 (2), 546-552, 2014
1972014
Intermolecular carbene S–H insertion catalysed by engineered myoglobin-based catalysts
V Tyagi, RB Bonn, R Fasan
Chemical science 6 (4), 2488-2494, 2015
1932015
Highly diastereo-and enantioselective synthesis of trifluoromethyl-substituted cyclopropanes via myoglobin-catalyzed transfer of trifluoromethylcarbene
A Tinoco, V Steck, V Tyagi, R Fasan
Journal of the American Chemical Society 139 (15), 5293-5296, 2017
1892017
Myoglobin-catalyzed intermolecular carbene N–H insertion with arylamine substrates
G Sreenilayam, R Fasan
Chemical Communications 51 (8), 1532-1534, 2015
1842015
Gram‐scale synthesis of chiral cyclopropane‐containing drugs and drug precursors with engineered myoglobin catalysts featuring complementary stereoselectivity
P Bajaj, G Sreenilayam, V Tyagi, R Fasan
Angewandte Chemie 128 (52), 16344-16348, 2016
1832016
Structure–activity studies in a family of β‐Hairpin protein epitope mimetic inhibitors of the p53–HDM2 protein–protein interaction
R Fasan, RLA Dias, K Moehle, O Zerbe, D Obrecht, PRE Mittl, MG Grütter, ...
ChemBioChem 7 (3), 515-526, 2006
1772006
Enzymatic C(sp3)-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones
R Singh, JN Kolev, PA Sutera, R Fasan
ACS catalysis 5 (3), 1685-1691, 2015
1722015
Chemo-enzymatic fluorination of unactivated organic compounds
A Rentmeister, FH Arnold, R Fasan
Nature Chemical Biology 5 (1), 26-28, 2009
1552009
Myoglobin‐Catalyzed C− H Functionalization of Unprotected Indoles
DA Vargas, A Tinoco, V Tyagi, R Fasan
Angewandte Chemie International Edition 57 (31), 9911-9915, 2018
1472018
Cyclopropanations via heme carbenes: Basic mechanism and effects of carbene substituent, protein axial ligand, and porphyrin substitution
Y Wei, A Tinoco, V Steck, R Fasan, Y Zhang
Journal of the American Chemical Society 140 (5), 1649-1662, 2017
1432017
Metal substitution modulates the reactivity and extends the reaction scope of myoglobin carbene transfer catalysts
G Sreenilayam, EJ Moore, V Steck, R Fasan
Advanced synthesis & catalysis 359 (12), 2076-2089, 2017
1422017
P450 fingerprinting method for rapid discovery of terpene hydroxylating P450 catalysts with diversified regioselectivity
K Zhang, S El Damaty, R Fasan
Journal of the American Chemical Society 133 (10), 3242-3245, 2011
1422011
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