| Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2 S Ortega, M Ittmann, SH Tsang, M Ehrlich, C Basilico Proceedings of the National Academy of Sciences 95 (10), 5672-5677, 1998 | 788 | 1998 |
| Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ... Cell 154 (2), 452-464, 2013 | 549 | 2013 |
| Unexpected mutations after CRISPR–Cas9 editing in vivo KA Schaefer, WH Wu, DF Colgan, SH Tsang, AG Bassuk, VB Mahajan Nature methods 14 (6), 547-548, 2017 | 479 | 2017 |
| A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ... Cell 159 (1), 200-214, 2014 | 435 | 2014 |
| Allele-specific chromosome removal after Cas9 cleavage in human embryos MV Zuccaro, J Xu, C Mitchell, D Marin, R Zimmerman, B Rana, ... Cell 183 (6), 1650-1664. e15, 2020 | 310 | 2020 |
| Viral delivery systems for CRISPR CL Xu, MZC Ruan, VB Mahajan, SH Tsang Viruses 11 (1), 28, 2019 | 257 | 2019 |
| Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia S Kohl, D Zobor, WC Chiang, N Weisschuh, J Staller, IG Menendez, ... Nature genetics 47 (7), 757-765, 2015 | 230 | 2015 |
| Role for the target enzyme in deactivation of photoreceptor G protein in vivo SH Tsang, ME Burns, PD Calvert, P Gouras, DA Baylor, SP Goff, ... Science 282 (5386), 117-121, 1998 | 229 | 1998 |
| Retinal degeneration in mice lacking the γ subunit of the rod cGMP phosphodiesterase SH Tsang, P Gouras, CK Yamashita, H Kjeldbye, J Fisher, DB Farber, ... Science 272 (5264), 1026-1029, 1996 | 218 | 1996 |
| Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa Y Li, YT Tsai, CW Hsu, D Erol, J Yang, WH Wu, RJ Davis, D Egli, ... Molecular medicine 18, 1312-1319, 2012 | 206 | 2012 |
| Precision medicine: genetic repair of retinitis pigmentosa in patient-derived stem cells AG Bassuk, A Zheng, Y Li, SH Tsang, VB Mahajan Scientific reports 6 (1), 19969, 2016 | 205 | 2016 |
| Quantitative fundus autofluorescence in recessive Stargardt disease TR Burke, T Duncker, RL Woods, JP Greenberg, J Zernant, SH Tsang, ... Investigative ophthalmology & visual science 55 (5), 2841-2852, 2014 | 197 | 2014 |
| Frequent hypomorphic alleles account for a significant fraction of ABCA4 disease and distinguish it from age-related macular degeneration J Zernant, W Lee, FT Collison, GA Fishman, YV Sergeev, K Schuerch, ... Journal of medical genetics 54 (6), 404-412, 2017 | 196 | 2017 |
| Analysis of the ABCA4 gene by next-generation sequencing J Zernant, C Schubert, KM Im, T Burke, CM Brown, GA Fishman, ... Investigative ophthalmology & visual science 52 (11), 8479-8487, 2011 | 180 | 2011 |
| Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ... JAMA ophthalmology 138 (6), 643-651, 2020 | 166 | 2020 |
| Analysis of the ABCA4 genomic locus in Stargardt disease J Zernant, Y Xie, C Ayuso, R Riveiro-Alvarez, MA Lopez-Martinez, ... Human molecular genetics 23 (25), 6797-6806, 2014 | 156 | 2014 |
| A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease NL Gomes, VC Greenstein, JN Carlson, SH Tsang, RT Smith, RE Carr, ... Investigative ophthalmology & visual science 50 (8), 3953-3959, 2009 | 154 | 2009 |
| Differentiation of hypothalamic-like neurons from human pluripotent stem cells L Wang, K Meece, DJ Williams, KA Lo, M Zimmer, G Heinrich, JM Carli, ... The Journal of clinical investigation 125 (2), 796-808, 2015 | 143 | 2015 |
| Gene therapy and genome surgery in the retina JE DiCarlo, VB Mahajan, SH Tsang The Journal of clinical investigation 128 (6), 2177-2188, 2018 | 139 | 2018 |
| Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors J Gong, O Sagiv, H Cai, SH Tsang, LV Del Priore Experimental eye research 86 (6), 957-965, 2008 | 139 | 2008 |