| Extended-spectrum beta-lactamases A Philippon, R Labia, G Jacoby Antimicrobial agents and chemotherapy 33 (8), 1131-1136, 1989 | 948 | 1989 |
| β-Lactamases of Kluyvera ascorbata, Probable Progenitors of Some Plasmid-Encoded CTX-M Types C Humeniuk, G Arlet, V Gautier, P Grimont, R Labia, A Philippon Antimicrobial agents and chemotherapy 46 (9), 3045-3049, 2002 | 488 | 2002 |
| Molecular and Biochemical Characterization of VEB-1, a Novel Class A Extended-Spectrum β-Lactamase Encoded by an Escherichia coli Integron Gene L Poirel, T Naas, M Guibert, EB Chaibi, R Labia, P Nordmann Antimicrobial agents and chemotherapy 43 (3), 573-581, 1999 | 350 | 1999 |
| Inhibitor-resistant TEM β-lactamases: phenotypic, genetic and biochemical characteristics EB Chaibi, D Sirot, G Paul, R Labia Journal of Antimicrobial Chemotherapy 43 (4), 447-458, 1999 | 346 | 1999 |
| Characterization of a novel extended-spectrum beta-lactamase from Pseudomonas aeruginosa P Nordmann, E Ronco, T Naas, C Duport, Y Michel-Briand, R Labia Antimicrobial Agents and Chemotherapy 37 (5), 962-969, 1993 | 341 | 1993 |
| Biochemical properties of a carbapenem-hydrolyzing beta-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli P Nordmann, S Mariotte, T Naas, R Labia, MH Nicolas Antimicrobial agents and chemotherapy 37 (5), 939-946, 1993 | 240 | 1993 |
| Close amino acid sequence relationship between the new plasmid-mediated extended-spectrum β-lactamase MEN-1 and chromosomally encoded enzymes of Klebsiella oxytoca M Barthélémy, J Péduzzi, H Bernard, C Tancrède, R Labia Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1992 | 205 | 1992 |
| A structure-based classification of class A β-lactamases, a broadly diverse family of enzymes A Philippon, P Slama, P Dény, R Labia Clinical microbiology reviews 29 (1), 29-57, 2016 | 180 | 2016 |
| Clinical isolates of Escherichia coli producing TRI β-lactamases: novel TEM-enzymes conferring resistance to β-lactamase inhibitors G Videl, A Belaaouaj, L Gilly, R Labia, A Philippon, P Nevot, G Paul Journal of Antimicrobial Chemotherapy 30 (4), 449-462, 1992 | 168 | 1992 |
| A complex mutant of TEM-1 beta-lactamase with mutations encountered in both IRT-4 and extended-spectrum TEM-15, produced by an Escherichia coli clinical isolate D Sirot, C Recule, EB Chaibi, L Bret, J Croize, C Chanal-Claris, R Labia, ... Antimicrobial agents and chemotherapy 41 (6), 1322-1325, 1997 | 164 | 1997 |
| Computerized microacidimetric determination of-lactamase Michaelis-Menten constants R Labia, J Andrillon, F Le Goffic FEBS Lett 33, 42-44, 1973 | 150 | 1973 |
| Single amino acid substitution between SHV-1 β-lactamase and cefotaxime-hydrolyzing SHV-2 enzyme M Barthélémy, J Péduzzi, HB Yaghlane, R Labia FEBS letters 231 (1), 217-220, 1988 | 130 | 1988 |
| Synthesis and antimicrobial activities of N-substituted imides F Zentz, A Valla, R Le Guillou, R Labia, AG Mathot, D Sirot Il Farmaco 57 (5), 421-426, 2002 | 129 | 2002 |
| Site-directed mutagenesis at the active site of Escherichia coli TEM-1 beta-lactamase. Suicide inhibitor-resistant mutants reveal the role of arginine 244 and methionine 69 in … M Delaire, R Labia, JP Samama, JM Masson Journal of Biological Chemistry 267 (29), 20600-20606, 1992 | 124 | 1992 |
| A novel plasmid-medlated extended-spectrum β-lactamase not derived from TEM-or SHV-type enzymes H Bernard, C Tancrede, V Livrelli, A Morand, M Barthelemy, R Labia Journal of Antimicrobial Chemotherapy 29 (5), 590-592, 1992 | 123 | 1992 |
| Complete amino acid sequence of p453-plasmid-mediated PIT-2 β-lactamase (SHV-1) M Barthélémy, J Peduzzi, R Labia Biochemical Journal 251 (1), 73-79, 1988 | 121 | 1988 |
| New syntheses and potential antimalarial activities of new ‘retinoid-like chalcones’ A Valla, B Valla, D Cartier, R Le Guillou, R Labia, L Florent, S Charneau, ... European Journal of Medicinal Chemistry 41 (1), 142-146, 2006 | 120 | 2006 |
| Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate G Barnaud, R Labia, L Raskine, MJ Sanson-Le Pors, A Philippon, G Arlet FEMS microbiology letters 195 (2), 185-190, 2001 | 120 | 2001 |
| Chromosomally Encoded AmpC-Type β-Lactamase in a Clinical Isolate of Proteus mirabilis L Bret, C Chanal-Claris, D Sirot, EB Chaibi, R Labia, J Sirot Antimicrobial agents and chemotherapy 42 (5), 1110-1114, 1998 | 115 | 1998 |
| X-ray analysis of the NMC-A β-lactamase at 1.64-Å resolution, a class A carbapenemase with broad substrate specificity P Swarén, L Maveyraud, X Raquet, S Cabantous, C Duez, JD Pedelacq, ... Journal of Biological Chemistry 273 (41), 26714-26721, 1998 | 109 | 1998 |
