| mTOR regulates memory CD8 T-cell differentiation K Araki, AP Turner, VO Shaffer, S Gangappa, SA Keller, MF Bachmann, ... Nature 460 (7251), 108-112, 2009 | 1782 | 2009 |
| Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways CP Larsen, ET Elwood, DZ Alexander, SC Ritchie, R Hendrix, ... Nature 381 (6581), 434-438, 1996 | 1772 | 1996 |
| Rapid cloning of high-affinity human monoclonal antibodies against influenza virus J Wrammert, K Smith, J Miller, WA Langley, K Kokko, C Larsen, NY Zheng, ... Nature 453 (7195), 667-671, 2008 | 1276 | 2008 |
| Costimulation blockade with belatacept in renal transplantation F Vincenti, C Larsen, A Durrbach, T Wekerle, B Nashan, G Blancho, ... New England Journal of Medicine 353 (8), 770-781, 2005 | 1046 | 2005 |
| A phase III study of belatacept‐based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study) F Vincenti, B Charpentier, Y Vanrenterghem, L Rostaing, B Bresnahan, ... American Journal of Transplantation 10 (3), 535-546, 2010 | 1044 | 2010 |
| 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses WW Shuford, K Klussman, DD Tritchler, DT Loo, J Chalupny, AW Siadak, ... Journal of Experimental Medicine 186 (1), 47-55, 1997 | 999 | 1997 |
| Improvement in outcomes of clinical islet transplantation: 1999–2010 FB Barton, MR Rickels, R Alejandro, BJ Hering, S Wease, B Naziruddin, ... Diabetes care 35 (7), 1436-1445, 2012 | 909 | 2012 |
| Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties CP Larsen, TC Pearson, AB Adams, P Tso, N Shirasugi, E Strobertb, ... American Journal of Transplantation 5 (3), 443-453, 2005 | 834 | 2005 |
| Migration and maturation of Langerhans cells in skin transplants and explants. CP Larsen, RM Steinman, M Witmer-Pack, DF Hankins, PJ Morris, ... The Journal of experimental medicine 172 (5), 1483-1493, 1990 | 817 | 1990 |
| Belatacept and long-term outcomes in kidney transplantation F Vincenti, L Rostaing, J Grinyo, K Rice, S Steinberg, L Gaite, MC Moal, ... New England Journal of Medicine 374 (4), 333-343, 2016 | 779 | 2016 |
| Heterologous immunity provides a potent barrier to transplantation tolerance AB Adams, MA Williams, TR Jones, N Shirasugi, MM Durham, SM Kaech, ... The Journal of clinical investigation 111 (12), 1887-1895, 2003 | 746 | 2003 |
| Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia BJ Hering, WR Clarke, ND Bridges, TL Eggerman, R Alejandro, MD Bellin, ... Diabetes care 39 (7), 1230-1240, 2016 | 732 | 2016 |
| Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection. CP Larsen, PJ Morris, JM Austyn The Journal of experimental medicine 171 (1), 307-314, 1990 | 682 | 1990 |
| Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways K Cardona, GS Korbutt, Z Milas, J Lyon, J Cano, W Jiang, H Bello-Laborn, ... Nature medicine 12 (3), 304-306, 2006 | 566 | 2006 |
| Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1. JA Roake, AS Rao, PJ Morris, CP Larsen, DF Hankins, JM Austyn The Journal of experimental medicine 181 (6), 2237-2247, 1995 | 564 | 1995 |
| Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. CP Larsen, SC Ritchie, R Hendrix, PS Linsley, KS Hathcock, RJ Hodes, ... Journal of immunology (Baltimore, Md.: 1950) 152 (11), 5208-5219, 1994 | 488 | 1994 |
| Transplantation tolerance induced by CTLA4-Ig1 TC Pearson, DZ Alexander, KJ Winn, PS Linsley, RP Lowry, CP Larsen Transplantation 57 (12), 1701-1705, 1994 | 449 | 1994 |
| CD40-gp39 INTERACTIONS PLAY A CRITICAL ROLE DURING ALLOGRAFT REJECTION: Suppression of Allograft Rejection by Blockade of the CD40-gp39 Pathway: 1 CP Larsen, DZ Alexander, D Hollenbaugh, ET Elwood, SC Ritchie, ... Transplantation 61 (1), 4-9, 1996 | 437 | 1996 |
| Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection J Trambley, AW Bingaman, A Lin, ET Elwood, SY Waitze, J Ha, ... The Journal of clinical investigation 104 (12), 1715-1722, 1999 | 412 | 1999 |
| Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations. CP Larsen, SC Ritchie, TC Pearson, PS Linsley, RP Lowry Journal of Experimental Medicine 176 (4), 1215-1220, 1992 | 406 | 1992 |