A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1 WM Botello-Smith, W Jiang, H Zhang, AD Ozkan, YC Lin, CN Pham, ... Nature communications 10 (1), 4503, 2019 | 209 | 2019 |
PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia X He, Y Zhu, YC Lin, M Li, J Du, H Dong, J Sun, L Zhu, H Wang, Z Ding, ... Blood, The Journal of the American Society of Hematology 134 (6), 548-560, 2019 | 77 | 2019 |
Crowding-induced opening of the mechanosensitive Piezo1 channel in silico W Jiang, JS Del Rosario, W Botello-Smith, S Zhao, Y Lin, H Zhang, ... Communications Biology 4 (1), 84, 2021 | 44 | 2021 |
Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia Y Zhu, X He, YC Lin, H Dong, L Zhang, X Chen, Z Wang, Y Shen, M Li, ... Blood, The Journal of the American Society of Hematology 134 (15), 1257-1268, 2019 | 35 | 2019 |
Structural and thermodynamic framework for PIEZO1 modulation by small molecules W Jiang, TD Wijerathne, H Zhang, YC Lin, S Jo, W Im, JJ Lacroix, YL Luo Proceedings of the National Academy of Sciences 120 (50), e2310933120, 2023 | 11 | 2023 |
Mechanical properties of anionic asymmetric bilayers from atomistic simulations W Jiang, YC Lin, YL Luo The Journal of Chemical Physics 154 (22), 2021 | 9 | 2021 |
Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning W Jiang, YC Lin, W Botello-Smith, JE Contreras, AL Harris, L Maragliano, ... Biophysical Journal 120 (15), 2969-2983, 2021 | 8 | 2021 |
Large-pore connexin hemichannels function like molecule transporters independent of ion conduction PS Gaete, D Kumar, CI Fernandez, JM Valdez Capuccino, A Bhatt, ... Proceedings of the National Academy of Sciences 121 (33), e2403903121, 2024 | 2 | 2024 |
Binding Free Energies of Piezo1 Channel Agonists at Protein-Membrane Interface W Jiang, H Zhang, W Im, JJ Lacroix, YL Luo bioRxiv, 2022.06. 27.497657, 2022 | 2 | 2022 |
Single-Channel Permeability from Markovian Milestoning, Umbrella Sampling, and Voltage Simulations YC Lin, Y Luo | 2* | 2021 |
Rationale design of novel PIEZO1 modulators W Jiang, TD Wijerathne, H Zhang, YC Lin, W Im, JJ Lacroix, YL Luo Biophysical Journal 122 (3), 396a, 2023 | 1 | 2023 |
Free energy and kinetics of cAMP permeation through connexin26 hemichannel with and without voltage W Jiang, YC Lin, W Botello-Smith, J Contreras, AL Harris, L Maragliano, ... bioRxiv, 2021.01. 18.427208, 2021 | 1 | 2021 |
A piezo1 open state reveals a multi-fenestrated ion permeation pathway W Jiang, JS Del Rosario, W Botello-Smith, S Zhao, Y Lin, H Zhang, ... bioRxiv, 2020.03. 12.988378, 2020 | 1 | 2020 |
Dissecting current rectification through asymmetric nanopores Y Lin, JJ Lacroix, J Sterling, YL Luo bioRxiv, 2024.11. 14.623680, 2024 | | 2024 |
Large-pore connexin hemichannels function as molecule transporters independently of ion conduction PS Gaete, D Kumar, CI Fernandez, JM Valdez-Capuccino, A Bhatt, ... bioRxiv, 2024.02. 20.581300, 2024 | | 2024 |
Refining HCN1 channel closed and open state models using cysteine bridge simulations YC Lin, PH Larsson, YL Luo Biophysical journal 122 (3), 193a, 2023 | | 2023 |
Small molecule permeation through a wide-pore channel via applied voltage and Markovian milestoning YC Lin, W Jiang, YL Luo Biophysical Journal 121 (3), 248a, 2022 | | 2022 |
Computer simulations of Piezo1 channel regulation by membrane and small molecule YL Luo, W Jiang, YC Lin, H Zhang, WM Botello-Smith Biophysical Journal 121 (3), 187a-188a, 2022 | | 2022 |
An Open State Was Induced by Mimicking Mechanosensitive Piezo1 Channel Clusters in Molecular Dynamic Simulations W Jiang, J Del Rosario, WM Botello-Smith, S Zhao, Y Lin, H Zhang, ... Biophysical Journal 120 (3), 228a, 2021 | | 2021 |
In Silico Transmission of Cyclic Amp through Connexin 26 via Milestoning and External Electric Field Molecular Dynamics Simulations WM Botello-Smith, Y Lin, W Jiang, L Maragliano, JE Contreras, AL Harris, ... Biophysical Journal 120 (3), 178a, 2021 | | 2021 |