Preclinical comparison of osimertinib with other EGFR-TKIs in EGFR-mutant NSCLC brain metastases models, and early evidence of clinical brain metastases activity P Ballard, JWT Yates, Z Yang, DW Kim, JCH Yang, M Cantarini, K Pickup, ... Clinical Cancer Research 22 (20), 5130-5140, 2016 | 712 | 2016 |
Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain K Varnäs, C Halldin, H Hall Human brain mapping 22 (3), 246-260, 2004 | 399 | 2004 |
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models ST Durant, L Zheng, Y Wang, K Chen, L Zhang, T Zhang, Z Yang, ... Science advances 4 (6), eaat1719, 2018 | 285 | 2018 |
Clinical validation of 18F-AZD4694, an amyloid-β–specific PET radioligand Z Cselényi, ME Jönhagen, A Forsberg, C Halldin, P Julin, M Schou, ... Journal of Nuclear Medicine 53 (3), 415-424, 2012 | 266 | 2012 |
Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication R Nesvåg, G Lawyer, K Varnäs, AM Fjell, KB Walhovd, A Frigessi, ... Schizophrenia research 98 (1-3), 16-28, 2008 | 249 | 2008 |
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson’s disease A Jucaite, P Svenningsson, JO Rinne, Z Cselenyi, K Varnäs, P Johnström, ... Brain 138 (9), 2687-2700, 2015 | 220 | 2015 |
Preclinical comparison of the blood–brain barrier permeability of osimertinib with other EGFR TKIs N Colclough, K Chen, P Johnström, N Strittmatter, Y Yan, GL Wrigley, ... Clinical Cancer Research 27 (1), 189-201, 2021 | 170 | 2021 |
Distribution of 5-HT7 receptors in the human brain: a preliminary autoradiographic study using [3H] SB-269970 K Varnäs, DR Thomas, E Tupala, J Tiihonen, H Hall Neuroscience letters 367 (3), 313-316, 2004 | 147 | 2004 |
Autoradiographic mapping of 5-HT1B and 5-HT1D receptors in the post mortem human brain using [3H] GR 125743 K Varnäs, H Hall, P Bonaventure, G Sedvall Brain research 915 (1), 47-57, 2001 | 139 | 2001 |
The 5-HT1B receptor-a potential target for antidepressant treatment M Tiger, K Varnäs, Y Okubo, J Lundberg Psychopharmacology 235 (5), 1317-1334, 2018 | 114 | 2018 |
Detection of amyloid in Alzheimer’s disease with positron emission tomography using [11C]AZD2184 S Nyberg, ME Jönhagen, Z Cselényi, C Halldin, P Julin, H Olsson, ... European journal of nuclear medicine and molecular imaging 36, 1859-1863, 2009 | 101 | 2009 |
Distribution of 5-HT4 receptors in the postmortem human brain—an autoradiographic study using [125I] SB 207710 K Varnäs, C Halldin, VW Pike, H Hall European Neuropsychopharmacology 13 (4), 228-234, 2003 | 97 | 2003 |
Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects A Jučaite, Z Cselényi, A Arvidsson, G Åhlberg, P Julin, K Varnäs, ... EJNMMI research 2, 1-13, 2012 | 91 | 2012 |
[11C] AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain ME Pierson, J Andersson, S Nyberg, DJ McCarthy, SJ Finnema, K Varnäs, ... Neuroimage 41 (3), 1075-1085, 2008 | 85 | 2008 |
Quantitative Analysis of [11C]AZ10419369 Binding to 5-HT1B Receptors in Human Brain K Varnäs, S Nyberg, C Halldin, A Varrone, A Takano, P Karlsson, ... Journal of Cerebral Blood Flow & Metabolism 31 (1), 113-123, 2011 | 83 | 2011 |
Regional expression of 5‐HT1B receptor mRNA in the human brain K Varnäs, YL Hurd, H Hall Synapse 56 (1), 21-28, 2005 | 62 | 2005 |
PET imaging of [11C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding K Varnäs, Z Cselényi, A Jucaite, C Halldin, P Svenningsson, L Farde, ... European journal of nuclear medicine and molecular imaging 46, 367-375, 2019 | 58 | 2019 |
Synthesis and biological evaluation of technetium (III) mixed-ligand complexes with high affinity for the cerebral 5-HT1A receptor and the alpha1-adrenergic receptor A Drews, HJ Pietzsch, R Syhre, S Seifert, K Varnäs, H Hall, C Halldin, ... Nuclear medicine and biology 29 (4), 389-398, 2002 | 58 | 2002 |
A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066—estimating occupancy in the absence of a reference region M Kågedal, Z Cselényi, S Nyberg, P Raboisson, L Ståhle, P Stenkrona, ... Neuroimage 82, 160-169, 2013 | 55 | 2013 |
Brain exposure of the ATM inhibitor AZD1390 in humans—a positron emission tomography study A Jucaite, P Stenkrona, Z Cselényi, S De Vita, N Buil-Bruna, K Varnäs, ... Neuro-oncology 23 (4), 687-696, 2021 | 53 | 2021 |