Extracellular histones are major mediators of death in sepsis J Xu, X Zhang, R Pelayo, M Monestier, CT Ammollo, F Semeraro, ... Nature medicine 15 (11), 1318-1321, 2009 | 1754 | 2009 |
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis P Carmeliet, MG Lampugnani, L Moons, F Breviario, V Compernolle, ... Cell 98 (2), 147-157, 1999 | 1624 | 1999 |
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration B Oosthuyse, L Moons, E Storkebaum, H Beck, D Nuyens, K Brusselmans, ... Nature genetics 28 (2), 131-138, 2001 | 1394 | 2001 |
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure S Heymans, A Luttun, D Nuyens, G Theilmeier, E Creemers, L Moons, ... Nature medicine 5 (10), 1135-1142, 1999 | 1026 | 1999 |
Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice V Compernolle, K Brusselmans, T Acker, P Hoet, M Tjwa, H Beck, ... Nature medicine 8 (7), 702-710, 2002 | 1002 | 2002 |
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 P Carmeliet, YS Ng, D Nuyens, G Theilmeier, K Brusselmans, ... Nature medicine 5 (5), 495-502, 1999 | 888 | 1999 |
Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation P Carmeliet, L Moons, R Lijnen, M Baes, V Lemaître, P Tipping, A Drew, ... Nature genetics 17 (4), 439-444, 1997 | 821 | 1997 |
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism J Aragonés, M Schneider, K Van Geyte, P Fraisl, T Dresselaers, ... Nature genetics 40 (2), 170-180, 2008 | 574 | 2008 |
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis A Angelillo-Scherrer, PG de Frutos, C Aparicio, E Melis, P Savi, F Lupu, ... Nature medicine 7 (2), 215-221, 2001 | 553 | 2001 |
Prelesional events in atherogenesis. Accumulation of extracellular cholesterol-rich liposomes in the arterial intima and cardiac valves of the hyperlipidemic rabbit N Simionescu, E Vasile, F Lupu, G Popescu, M Simionescu The American journal of pathology 123 (1), 109, 1986 | 376 | 1986 |
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2 BH Herzog, J Fu, SJ Wilson, PR Hess, A Sen, JM McDaniel, Y Pan, ... Nature 502 (7469), 105-109, 2013 | 372 | 2013 |
Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries. F Lupu, GE Bergonzelli, DA Heim, E Cousin, CY Genton, F Bachmann, ... Arteriosclerosis and Thrombosis: A Journal of Vascular Biology 13 (7), 1090-1100, 1993 | 358 | 1993 |
Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice P Carmeliet, L Moons, R Lijnen, S Janssens, F Lupu, D Collen, ... Circulation 96 (9), 3180-3191, 1997 | 355 | 1997 |
Persistence of atherosclerotic plaque but reduced aneurysm formation in mice with stromelysin-1 (MMP-3) gene inactivation J Silence, F Lupu, D Collen, HR Lijnen Arteriosclerosis, thrombosis, and vascular biology 21 (9), 1440-1445, 2001 | 311 | 2001 |
A genetic Xenopus laevis tadpole model to study lymphangiogenesis A Ny, M Koch, M Schneider, E Neven, RT Tong, S Maity, C Fischer, ... Nature medicine 11 (9), 998-1004, 2005 | 280 | 2005 |
Urokinase but not tissue plasminogen activator mediates arterial neointima formation in mice P Carmeliet, L Moons, JM Herbert, J Crawley, F Lupu, R Lijnen, D Collen Circulation research 81 (5), 829-839, 1997 | 280 | 1997 |
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice J Fu, H Gerhardt, JM McDaniel, B Xia, X Liu, L Ivanciu, A Ny, K Hermans, ... The Journal of clinical investigation 118 (11), 3725-3737, 2008 | 277 | 2008 |
Innate immunity and coagulation CT Esmon, J Xu, F Lupu Journal of Thrombosis and Haemostasis 9, 182-188, 2011 | 271 | 2011 |
Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes HR Lijnen, B Van Hoef, F Lupu, L Moons, P Carmeliet, D Collen Arteriosclerosis, thrombosis, and vascular biology 18 (7), 1035-1045, 1998 | 269 | 1998 |
Inflammation, innate immunity and blood coagulation J Xu, F Lupu, CT Esmon Hämostaseologie 30 (01), 5-9, 2010 | 261 | 2010 |