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Kurt Piepenbrink
Kurt Piepenbrink
Assistant Professor, The University of Nebraska Lincoln
Verifierad e-postadress på unl.edu - Startsida
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T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ...
Immunity 31 (6), 885-896, 2009
2372009
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes
KM Armstrong, KH Piepenbrink, BM Baker
Biochemical Journal 415 (2), 183-196, 2008
1732008
A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice
Z Yang, D Schmidt, W Liu, S Li, L Shi, J Sheng, K Chen, H Yu, ...
The Journal of infectious diseases 210 (6), 964-972, 2014
1132014
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics
OY Borbulevych, KH Piepenbrink, BM Baker
The Journal of Immunology 186 (5), 2950-2958, 2011
982011
Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism
DR Scott, OY Borbulevych, KH Piepenbrink, SA Corcelli, BM Baker
Journal of molecular biology 414 (3), 385-400, 2011
962011
Type IV pili promote early biofilm formation by Clostridium difficile
GA Maldarelli, KH Piepenbrink, AJ Scott, JA Freiberg, Y Song, ...
FEMS Pathogens and Disease 74 (6), ftw061, 2016
932016
Structural diversity in the type IV pili of multidrug-resistant Acinetobacter
KH Piepenbrink, E Lillehoj, CM Harding, JW Labonte, X Zuo, CA Rapp, ...
Journal of Biological Chemistry 291 (44), 22924-22935, 2016
912016
Motility and adhesion through type IV pili in Gram-positive bacteria
KH Piepenbrink, EJ Sundberg
Biochemical Society Transactions 44 (6), 1659-1666, 2016
892016
Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains
DH Aggen, AS Chervin, TM Schmitt, B Engels, JD Stone, SA Richman, ...
Gene therapy 19 (4), 365-374, 2012
802012
The structure of PilA from Acinetobacter baumannii AB5075 suggests a mechanism for functional specialization in Acinetobacter type IV pili
LA Ronish, E Lillehoj, JK Fields, EJ Sundberg, KH Piepenbrink
Journal of Biological Chemistry 294 (1), 218-230, 2019
772019
Structure-based design of hepatitis C virus vaccines that elicit neutralizing antibody responses to a conserved epitope
BG Pierce, EN Boucher, KH Piepenbrink, M Ejemel, CA Rapp, ...
Journal of virology 91 (20), 10.1128/jvi. 01032-17, 2017
722017
DNA uptake by type IV filaments
KH Piepenbrink
Frontiers in Molecular Biosciences 6, 1, 2019
692019
Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain
W Piao, LW Ru, KH Piepenbrink, EJ Sundberg, SN Vogel, VY Toshchakov
Proceedings of the National Academy of Sciences 110 (47), 19036-19041, 2013
652013
The basis for limited specificity and MHC restriction in a T cell receptor interface
KH Piepenbrink, SJ Blevins, DR Scott, BM Baker
Nature communications 4 (1), 1948, 2013
642013
How an alloreactive T-cell receptor achieves peptide and MHC specificity
Y Wang, NK Singh, TT Spear, LM Hellman, KH Piepenbrink, ...
Proceedings of the National Academy of Sciences 114 (24), E4792-E4801, 2017
612017
Structural and evolutionary analyses show unique stabilization strategies in the type IV pili of Clostridium difficile
KH Piepenbrink, GA Maldarelli, CFM De La Peña, TC Dingle, GL Mulvey, ...
Structure 23 (2), 385-396, 2015
602015
Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors
DH Aggen, AS Chervin, FK Insaidoo, KH Piepenbrink, BM Baker, ...
Protein Engineering, Design & Selection 24 (4), 361-372, 2011
602011
Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins
KH Piepenbrink, GA Maldarelli, CFM De La Peña, GL Mulvey, GA Snyder, ...
Journal of Biological Chemistry 289 (7), 4334-4345, 2014
512014
The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo
SW Hyun, A Liu, Z Liu, AS Cross, AC Verceles, S Magesh, Y Kommagalla, ...
Glycobiology 26 (8), 834-849, 2016
452016
Candida albicans quorum-sensing molecule farnesol modulates staphyloxanthin production and activates the thiol-based oxidative-stress response in Staphylococcus aureus
T Vila, EF Kong, A Ibrahim, K Piepenbrink, AC Shetty, C McCracken, ...
Virulence 10 (1), 625-642, 2019
432019
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Artiklar 1–20