Microglia-mediated neurotoxicity: uncovering the molecular mechanisms ML Block, L Zecca, JS Hong Nature Reviews Neuroscience 8 (1), 57-69, 2007 | 4806 | 2007 |
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration L Qin, X Wu, ML Block, Y Liu, GR Breese, JS Hong, DJ Knapp, FT Crews Glia 55 (5), 453-462, 2007 | 2508 | 2007 |
Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism ML Block, JS Hong Progress in neurobiology 76 (2), 77-98, 2005 | 1937 | 2005 |
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease W Zhang, T Wang, Z Pei, DS Miller, X Wu, ML Block, B Wilson, W Zhang, ... The FASEB Journal 19 (6), 533-542, 2005 | 1489 | 2005 |
Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention BIN Liu, JS Hong The Journal of pharmacology and experimental therapeutics 304 (1), 1-7, 2003 | 1399 | 2003 |
Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia WG Kim, RP Mohney, B Wilson, GH Jeohn, B Liu, JS Hong Journal of Neuroscience 20 (16), 6309-6316, 2000 | 1106 | 2000 |
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression HM Gao, JS Hong Trends in immunology 29 (8), 357-365, 2008 | 965 | 2008 |
Microglial activation‐mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease HM Gao, J Jiang, B Wilson, W Zhang, JS Hong, B Liu Journal of neurochemistry 81 (6), 1285-1297, 2002 | 930 | 2002 |
NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia L Qin, Y Liu, T Wang, SJ Wei, ML Block, B Wilson, B Liu, JS Hong Journal of Biological Chemistry 279 (2), 1415-1421, 2004 | 699 | 2004 |
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action HJ Kim, M Rowe, M Ren, JS Hong, PS Chen, DM Chuang The Journal of pharmacology and experimental therapeutics 321 (3), 892-901, 2007 | 648 | 2007 |
Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment L Qin, J He, RN Hanes, O Pluzarev, JS Hong, FT Crews Journal of neuroinflammation 5, 1-17, 2008 | 630 | 2008 |
Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons HM Gao, JS Hong, W Zhang, B Liu Journal of Neuroscience 22 (3), 782-790, 2002 | 560 | 2002 |
Role of nitric oxide in inflammation‐mediated neurodegeneration BIN Liu, HUIM GAO, JIZYUH WANG, GHO JEOHN, CL Cooper, ... Annals of the New York academy of sciences 962 (1), 318-331, 2002 | 559 | 2002 |
Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation B Liu, L Du, JS Hong The Journal of pharmacology and experimental therapeutics 293 (2), 607-617, 2000 | 483 | 2000 |
Role of oxidative stress in epileptic seizures EJ Shin, JH Jeong, YH Chung, WK Kim, KH Ko, JH Bach, JS Hong, ... Neurochemistry international 59 (2), 122-137, 2011 | 479 | 2011 |
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase ML Block, X Wu, Z Pei, G Li, T Wang, L Qin, B Wilson, J Yang, JS Hong, ... The FASEB journal 18 (13), 1618-1620, 2004 | 449 | 2004 |
Chronic microglial activation and progressive dopaminergic neurotoxicity ML Block, JS Hong Biochemical Society Transactions 35 (5), 1127-1132, 2007 | 435 | 2007 |
HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration HM Gao, H Zhou, F Zhang, BC Wilson, W Kam, JS Hong Journal of Neuroscience 31 (3), 1081-1092, 2011 | 424 | 2011 |
Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes PS Chen, GS Peng, G Li, S Yang, X Wu, CC Wang, B Wilson, RB Lu, ... Molecular psychiatry 11 (12), 1116-1125, 2006 | 423 | 2006 |
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson’s disease HM Gao, F Zhang, H Zhou, W Kam, B Wilson, JS Hong Environmental health perspectives 119 (6), 807-814, 2011 | 411 | 2011 |