| Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models M Bergstrand, AC Hooker, JE Wallin, MO Karlsson The AAPS journal 13, 143-151, 2011 | 1464 | 2011 |
| Modeling and simulation workbench for NONMEM: tutorial on Pirana, PsN, and Xpose RJ Keizer, MO Karlsson, A Hooker CPT: pharmacometrics & systems pharmacology 2 (6), 1-9, 2013 | 725 | 2013 |
| Quantitative magnetic resonance imaging analysis of neovasculature volume in carotid atherosclerotic plaque W Kerwin, A Hooker, M Spilker, P Vicini, M Ferguson, T Hatsukami, ... Circulation 107 (6), 851-856, 2003 | 525 | 2003 |
| Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method AC Hooker, CE Staatz, MO Karlsson Pharmaceutical research 24, 2187-2197, 2007 | 428 | 2007 |
| Model evaluation of continuous data pharmacometric models: metrics and graphics THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ... CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017 | 358 | 2017 |
| POPED, a software for optimal experiment design in population kinetics M Foracchia, A Hooker, P Vicini, A Ruggeri Computer methods and programs in biomedicine 74 (1), 29-46, 2004 | 163 | 2004 |
| PopED: an extended, parallelized, nonlinear mixed effects models optimal design tool J Nyberg, S Ueckert, EA Strömberg, S Hennig, MO Karlsson, AC Hooker Computer methods and programs in biomedicine 108 (2), 789-805, 2012 | 122 | 2012 |
| Improved utilization of ADAS-cog assessment data through item response theory based pharmacometric modeling S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker, ... Pharmaceutical research 31, 2152-2165, 2014 | 101 | 2014 |
| Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies J Nyberg, C Bazzoli, K Ogungbenro, A Aliev, S Leonov, S Duffull, ... British journal of clinical pharmacology 79 (1), 6-17, 2015 | 98 | 2015 |
| Advanced methods for dose and regimen finding during drug development: summary of the EMA/EFPIA workshop on dose finding (London 4–5 December 2014) FT Musuamba, E Manolis, N Holford, SYA Cheung, LE Friberg, ... CPT: pharmacometrics & systems pharmacology 6 (7), 418-429, 2017 | 77 | 2017 |
| Population pharmacokinetic model for docetaxel in patients with varying degrees of liver function: incorporating cytochrome P450 3A activity measurements AC Hooker, AJ Ten Tije, MA Carducci, J Weber, E Garrett‐Mayer, ... Clinical Pharmacology & Therapeutics 84 (1), 111-118, 2008 | 72 | 2008 |
| A diagnostic tool for population models using non-compartmental analysis: the ncappc package for R C Acharya, AC Hooker, GY Türkyılmaz, S Jönsson, MO Karlsson Computer methods and programs in biomedicine 127, 83-93, 2016 | 70 | 2016 |
| Robust population pharmacokinetic experiment design MG Dodds, AC Hooker, P Vicini Journal of Pharmacokinetics and Pharmacodynamics 32, 33-64, 2005 | 68 | 2005 |
| Simultaneous population optimal design for pharmacokinetic-pharmacodynamic experiments A Hooker, P Vicini The AAPS journal 7, E759-E785, 2005 | 62 | 2005 |
| A fast method for testing covariates in population PK/PD models A Khandelwal, K Harling, EN Jonsson, AC Hooker, MO Karlsson The AAPS journal 13, 464-472, 2011 | 57 | 2011 |
| Simultaneous optimal experimental design on dose and sample times J Nyberg, MO Karlsson, AC Hooker Journal of pharmacokinetics and pharmacodynamics 36, 125-145, 2009 | 56 | 2009 |
| Modeling subpopulations with the $ MIXTURE subroutine in NONMEM: finding the individual probability of belonging to a subpopulation for the use in model analysis and improved … KC Carlsson, RM Savi, AC Hooker, MO Karlsson The AAPS journal 11, 148-154, 2009 | 56 | 2009 |
| An evaluation of population D-optimal designs via pharmacokinetic simulations AC Hooker, M Foracchia, MG Dodds, P Vicini Annals of biomedical engineering 31, 98-111, 2003 | 56 | 2003 |
| A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066—estimating occupancy in the absence of a reference region M Kågedal, Z Cselényi, S Nyberg, P Raboisson, L Ståhle, P Stenkrona, ... Neuroimage 82, 160-169, 2013 | 55 | 2013 |
| Model selection and averaging of nonlinear mixed-effect models for robust phase III dose selection Y Aoki, D Röshammar, B Hamrén, AC Hooker Journal of pharmacokinetics and pharmacodynamics 44, 581-597, 2017 | 46 | 2017 |
Mats KarlssonUppsala UniversityVerifierad e-postadress på farmaci.uu.se
