Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics RH Ho, RG Tirona, BF Leake, H Glaeser, W Lee, CJ Lemke, Y Wang, ... Gastroenterology 130 (6), 1793-1806, 2006 | 698 | 2006 |
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ... Nature medicine 9 (2), 220-224, 2003 | 547 | 2003 |
Intestinal drug transporter expression and the impact of grapefruit juice in humans H Glaeser, DG Bailey, GK Dresser, JC Gregor, UI Schwarz, JS McGrath, ... Clinical Pharmacology & Therapeutics 81 (3), 362-370, 2007 | 503 | 2007 |
Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2) W Lee, H Glaeser, LH Smith, RL Roberts, GW Moeckel, G Gervasini, ... Journal of Biological Chemistry 280 (10), 9610-9617, 2005 | 430 | 2005 |
Transporters and renal drug elimination W Lee, RB Kim Annu. Rev. Pharmacol. Toxicol. 44 (1), 137-166, 2004 | 285 | 2004 |
Effect of drug transporter genotypes on pravastatin disposition in European-and African-American participants RH Ho, L Choi, W Lee, G Mayo, UI Schwarz, RG Tirona, DG Bailey, ... Pharmacogenetics and genomics 17 (8), 647-656, 2007 | 223 | 2007 |
Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition RH Ho, BF Leake, RL Roberts, W Lee, RB Kim Journal of Biological Chemistry 279 (8), 7213-7222, 2004 | 207 | 2004 |
Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development W Lee, AC Lockhart, RB Kim, ML Rothenberg The Oncologist 10 (2), 104-111, 2005 | 191 | 2005 |
Overexpression of OATP1B3 confers apoptotic resistance in colon cancer W Lee, A Belkhiri, AC Lockhart, N Merchant, H Glaeser, EI Harris, ... Cancer research 68 (24), 10315-10323, 2008 | 163 | 2008 |
Surface modification of polymer nanoparticles with native albumin for enhancing drug delivery to solid tumors H Hyun, J Park, K Willis, JE Park, LT Lyle, W Lee, Y Yeo Biomaterials 180, 206-224, 2018 | 141 | 2018 |
Next-generation proteasome inhibitors for cancer therapy JE Park, Z Miller, Y Jun, W Lee, KB Kim Translational Research 198, 1-16, 2018 | 141 | 2018 |
A phase I trial of SJG-136 (NSC# 694501) in advanced solid tumors YY Janjigian, W Lee, MG Kris, VA Miller, LM Krug, CG Azzoli, E Senturk, ... Cancer chemotherapy and pharmacology 65 (5), 833-838, 2010 | 128 | 2010 |
Inhibitors of the Immunoproteasome: Current Status and Future Directions. Z Miller, L Ao, KB Kim, W Lee Current pharmaceutical design, 2012 | 123 | 2012 |
Hepatic uptake of the novel antifungal agent caspofungin P Sandhu, W Lee, X Xu, BF Leake, M Yamazaki, JA Stone, JH Lin, ... Drug metabolism and disposition 33 (5), 676-682, 2005 | 121 | 2005 |
Role of organic anion-transporting polypeptides (OATPs) in cancer therapy N Thakkar, AC Lockhart, W Lee The AAPS journal 17, 535-545, 2015 | 111 | 2015 |
A Cancer-Specific Variant of the SLCO1B3 Gene Encodes a Novel Human Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Localized Mainly in the … N Thakkar, K Kim, ER Jang, S Han, K Kim, D Kim, N Merchant, ... Molecular pharmaceutics 10 (1), 406-416, 2013 | 102 | 2013 |
Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids NS Nagathihalli, Y Beesetty, W Lee, MK Washington, X Chen, ... Cancer research 74 (7), 2062-2072, 2014 | 101 | 2014 |
Phase 0/microdosing approaches: time for mainstream application in drug development? T Burt, G Young, W Lee, H Kusuhara, O Langer, M Rowland, Y Sugiyama Nature Reviews Drug Discovery 19 (11), 801-818, 2020 | 90 | 2020 |
A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression C Marzolini, RG Tirona, G Gervasini, B Poonkuzhali, M Assem, W Lee, ... Molecular endocrinology 21 (8), 1769-1780, 2007 | 81 | 2007 |
Development of Peptide-Based Reversing Agents for P-Glycoprotein-Mediated Resistance to Carfilzomib L Ao, Y Wu, D Kim, ER Jang, K Kim, D Lee, KB Kim, W Lee Molecular Pharmaceutics 9 (8), 2197-2205, 2012 | 70 | 2012 |