| Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA W Yu, D Gius, P Onyango, K Muldoon-Jacobs, J Karp, AP Feinberg, H Cui Nature 451 (7175), 202-206, 2008 | 1041 | 2008 |
| Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress R Tao, MC Coleman, JD Pennington, O Ozden, SH Park, H Jiang, HS Kim, ... Molecular cell 40 (6), 893-904, 2010 | 1030 | 2010 |
| SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, N Aykin-Burns, ... Cancer cell 17 (1), 41-52, 2010 | 938 | 2010 |
| Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology DR Spitz, EI Azzam, J Jian Li, D Gius Cancer and Metastasis Reviews 23, 311-322, 2004 | 883 | 2004 |
| Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice CB Peek, AH Affinati, KM Ramsey, HY Kuo, W Yu, LA Sena, O Ilkayeva, ... Science 342 (6158), 1243417, 2013 | 703 | 2013 |
| SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ... Cancer cell 20 (4), 487-499, 2011 | 619 | 2011 |
| Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation AA Kendrick, M Choudhury, SM Rahman, CE McCurdy, M Friederich, ... Biochemical Journal 433 (3), 505-514, 2011 | 443 | 2011 |
| Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3 VB Pillai, S Samant, NR Sundaresan, H Raghuraman, G Kim, MY Bonner, ... Nature communications 6 (1), 6656, 2015 | 419 | 2015 |
| Ionizing radiation-induced oxidative stress alters miRNA expression NL Simone, BP Soule, D Ly, AD Saleh, JE Savage, W DeGraff, J Cook, ... PloS one 4 (7), e6377, 2009 | 395 | 2009 |
| Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death RL Aft, FW Zhang, D Gius British journal of cancer 87 (7), 805-812, 2002 | 395 | 2002 |
| Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D: Cdk4/6 complexes results in active pRb SA Ezhevsky, H Nagahara, AM Vocero-Akbani, DR Gius, MC Wei, ... Proceedings of the National Academy of Sciences 94 (20), 10699-10704, 1997 | 395 | 1997 |
| Intracellular oxidation/reduction status in the regulation of transcription factors NF-κB and AP-1 D Gius, A Botero, S Shah, HA Curry Toxicology letters 106 (2-3), 93-106, 1999 | 374 | 1999 |
| Oxidative stress, redox, and the tumor microenvironment JA Cook, D Gius, DA Wink, MC Krishna, A Russo, JB Mitchell Seminars in radiation oncology 14 (3), 259-266, 2004 | 359 | 2004 |
| Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair S Zhang, S Weinberg, M DeBerge, A Gainullina, M Schipma, JM Kinchen, ... Cell metabolism 29 (2), 443-456. e5, 2019 | 352 | 2019 |
| Calorie restriction alters mitochondrial protein acetylation B Schwer, M Eckersdorff, Y Li, JC Silva, D Fermin, MV Kurtev, ... Aging cell 8 (5), 604-606, 2009 | 317 | 2009 |
| SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression KM Jacobs, JD Pennington, KS Bisht, N Aykin-Burns, HS Kim, M Mishra, ... International journal of biological sciences 4 (5), 291, 2008 | 317 | 2008 |
| Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements D Gius, X Cao, FJ Rauscher, DR Cohen, T Curran, VP Sukhatme Molecular and cellular biology 10 (8), 4243-4255, 1990 | 267 | 1990 |
| Therapy-induced senescence: opportunities to improve anticancer therapy PG Prasanna, DE Citrin, J Hildesheim, MM Ahmed, S Venkatachalam, ... JNCI: Journal of the National Cancer Institute 113 (10), 1285-1298, 2021 | 259 | 2021 |
| Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity EG Mimnaugh, W Xu, M Vos, X Yuan, JS Isaacs, KS Bisht, D Gius, ... Molecular cancer therapeutics 3 (5), 551-566, 2004 | 259 | 2004 |
| Redox signaling in cancer biology D Gius, DR Spitz Antioxidants & redox signaling 8 (7-8), 1249-1252, 2006 | 252 | 2006 |
Douglas SpitzProfessor of Radiation Oncology, University of IowaVerifierad e-postadress på uiowa.edu