Regulation of alternative macrophage activation by galectin-3 AC MacKinnon, SL Farnworth, PS Hodkinson, NC Henderson, ... The Journal of Immunology 180 (4), 2650-2658, 2008 | 698 | 2008 |
Regulation of transforming growth factor-β1–driven lung fibrosis by galectin-3 AC MacKinnon, MA Gibbons, SL Farnworth, H Leffler, UJ Nilsson, ... American journal of respiratory and critical care medicine 185 (5), 537-546, 2012 | 600 | 2012 |
Functional Adaptation of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin M Aspholm-Hurtig, G Dailide, M Lahmann, A Kalia, D Ilver, N Roche, ... Science 305 (5683), 519-522, 2004 | 513 | 2004 |
Structural and thermodynamic studies on cation− π interactions in lectin− ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine− arene … P Sörme, P Arnoux, B Kahl-Knutsson, H Leffler, JM Rini, UJ Nilsson Journal of the American Chemical Society 127 (6), 1737-1743, 2005 | 304 | 2005 |
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease A Boza-Serrano, R Ruiz, R Sanchez-Varo, J García-Revilla, Y Yang, ... Acta neuropathologica 138, 251-273, 2019 | 280 | 2019 |
Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3 C Diehl, O Engstrom, T Delaine, M Håkansson, S Genheden, K Modig, ... Journal of the American Chemical Society 132 (41), 14577-14589, 2010 | 252 | 2010 |
Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface S Carlsson, CT Öberg, MC Carlsson, A Sundin, UJ Nilsson, D Smith, ... Glycobiology 17 (6), 663-676, 2007 | 235 | 2007 |
Fluorescence polarization as an analytical tool to evaluate galectin–ligand interactions P Sörme, B Kahl-Knutsson, M Huflejt, UJ Nilsson, H Leffler Analytical biochemistry 334 (1), 36-47, 2004 | 228 | 2004 |
C2‐Symmetrical Thiodigalactoside Bis‐Benzamido Derivatives as High‐Affinity Inhibitors of Galectin‐3: Efficient Lectin Inhibition through Double Arginine–Arene … I Cumpstey, A Sundin, H Leffler, UJ Nilsson Angewandte Chemie 117 (32), 5240-5242, 2005 | 207 | 2005 |
Galectin‐3‐binding glycomimetics that strongly reduce bleomycin‐induced lung fibrosis and modulate intracellular glycan recognition T Delaine, P Collins, A MacKinnon, G Sharma, J Stegmayr, VK Rajput, ... ChemBioChem 17 (18), 1759-1770, 2016 | 194 | 2016 |
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis N Hirani, AC MacKinnon, L Nicol, P Ford, H Schambye, A Pedersen, ... European Respiratory Journal 57 (5), 2021 | 192 | 2021 |
The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics K Saraboji, M Håkansson, S Genheden, C Diehl, J Qvist, U Weininger, ... Biochemistry 51 (1), 296-306, 2012 | 191 | 2012 |
Ligand induced galectin-3 protein self-association A Lepur, E Salomonsson, UJ Nilsson, H Leffler Journal of Biological Chemistry 287 (26), 21751-21756, 2012 | 187 | 2012 |
Determination of the Degree of Branching in Normal and Amylopectin Type Potato Starch with 1H‐NMR Spectroscopy Improved resolution and two‐dimensional … GS Nilsson, L Gorton, KE Bergquist, U Nilsson Starch‐Stärke 48 (10), 352-357, 1996 | 181 | 1996 |
Low Micromolar Inhibitors of Galectin‐3 Based on 3′‐Derivatization of N‐Acetyllactosamine P Sörme, Y Qian, PG Nyholm, H Leffler, UJ Nilsson ChemBioChem 3 (2‐3), 183-189, 2002 | 171 | 2002 |
1H-1, 2, 3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors BA Salameh, I Cumpstey, A Sundin, H Leffler, UJ Nilsson Bioorganic & medicinal chemistry 18 (14), 5367-5378, 2010 | 151 | 2010 |
Galectin‐3 deficiency prevents concanavalin A–induced hepatitis in mice V Volarevic, M Milovanovic, B Ljujic, N Pejnovic, N Arsenijevic, U Nilsson, ... Hepatology 55 (6), 1954-1964, 2012 | 149 | 2012 |
3-(1, 2, 3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3 BA Salameh, H Leffler, UJ Nilsson Bioorganic & Medicinal Chemistry Letters 15 (14), 3344-3346, 2005 | 145 | 2005 |
Mutational tuning of galectin-3 specificity and biological function E Salomonsson, MC Carlsson, V Osla, R Hendus-Altenburger, ... Journal of Biological Chemistry 285 (45), 35079-35091, 2010 | 144 | 2010 |
C2-Symmetric Macrocyclic Carbohydrate/Amino Acid Hybrids through Copper(I)-Catalyzed Formation of 1,2,3-Triazoles JF Billing, UJ Nilsson The Journal of Organic Chemistry 70 (12), 4847-4850, 2005 | 143 | 2005 |