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zhu xiaopeng
zhu xiaopeng
Hainan University
Verifierad e-postadress på hainanu.edu.cn
Titel
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Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist
S Luo, D Zhangsun, PJ Harvey, Q Kaas, Y Wu, X Zhu, Y Hu, X Li, ...
Proceedings of the National Academy of Sciences 112 (30), E4026-E4035, 2015
1172015
Characterization of a Novel α-Conotoxin TxID from Conus textile That Potently Blocks Rat α3β4 Nicotinic Acetylcholine Receptors
S Luo, D Zhangsun, X Zhu, Y Wu, Y Hu, S Christensen, PJ Harvey, ...
Journal of medicinal chemistry 56 (23), 9655-9663, 2013
842013
A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors
S Luo, D Zhangsun, CI Schroeder, X Zhu, Y Hu, Y Wu, MM Weltzin, ...
The FASEB Journal 28 (4), 1842, 2014
812014
Atypical α-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor
S Luo, KB Akondi, D Zhangsun, Y Wu, X Zhu, Y Hu, S Christensen, ...
Journal of Biological Chemistry 285 (16), 12355-12366, 2010
812010
Toxic Effects of TiO2 NPs on Zebrafish
T Tang, Z Zhang, X Zhu
International journal of environmental research and public health 16 (4), 523, 2019
752019
A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily
S Luo, S Christensen, D Zhangsun, Y Wu, Y Hu, X Zhu, S Chhabra, ...
PloS one 8 (1), e54648, 2013
712013
Characterization of a novel α-conotoxin from conus textile that selectively targets α6/α3β2β3 nicotinic acetylcholine receptors
S Luo, D Zhangsun, Y Wu, X Zhu, Y Hu, M McIntyre, S Christensen, ...
Journal of Biological Chemistry 288 (2), 894-902, 2013
662013
From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR
B Lin, M Xu, X Zhu, Y Wu, X Liu, D Zhangsun, Y Hu, SH Xiang, ...
Scientific reports 6 (1), 22349, 2016
502016
α-Conotoxin [S9A] TxID potently discriminates between α3β4 and α6/α3β4 nicotinic acetylcholine receptors
Y Wu, D Zhangsun, X Zhu, Q Kaas, M Zhangsun, PJ Harvey, DJ Craik, ...
Journal of medicinal chemistry 60 (13), 5826-5833, 2017
372017
αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 …
D Zhangsun, X Zhu, Q Kaas, Y Wu, DJ Craik, JM McIntosh, S Luo
Neuropharmacology 127, 243-252, 2017
342017
Novel O‐superfamily Conotoxins Identified by cDNA Cloning From Three Vermivorous Conus Species
D Zhangsun, S Luo, Y Wu, X Zhu, Y Hu, L Xie
Chemical biology & drug design 68 (5), 256-265, 2006
332006
The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
M Xu, X Zhu, J Yu, J Yu, S Luo, X Wang
Protein & cell 8 (9), 675-685, 2017
322017
High selectivity of an α-conotoxin LvIA analogue for α3β2 nicotinic acetylcholine receptors is mediated by β2 functionally important residues
X Zhu, S Pan, M Xu, L Zhang, J Yu, J Yu, Y Wu, Y Fan, H Li, ...
Journal of Medicinal Chemistry 63 (22), 13656-13668, 2020
302020
d-Amino Acid Substitution of α-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability
J Ren, X Zhu, P Xu, R Li, Y Fu, S Dong, D Zhangsun, Y Wu, S Luo
Marine drugs 17 (3), 142, 2019
282019
The effects of exopolysaccharides and exopolysaccharide-producing Lactobacillus on the intestinal microbiome of zebrafish (Danio rerio)
C Ma, H Guo, H Chang, S Huang, S Jiang, D Huo, J Zhang, X Zhu
BMC microbiology 20, 1-11, 2020
262020
Expression, renaturation and biological activity of recombinant conotoxin GeXIVAWT
B Gao, D Zhangsun, Y Wu, B Lin, X Zhu, S Luo
Applied microbiology and biotechnology 97, 1223-1230, 2013
262013
Potassium sorbate suppresses intestinal microbial activity and triggers immune regulation in zebrafish (Danio rerio)
Q Peng, H Chang, R Wang, Z You, S Jiang, C Ma, D Huo, X Zhu, J Zhang
Food & function 10 (11), 7164-7173, 2019
252019
Single amino acid substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic acetylcholine receptor antagonist
J Yu, X Zhu, PJ Harvey, Q Kaas, D Zhangsun, DJ Craik, S Luo
Journal of medicinal chemistry 61 (20), 9256-9265, 2018
252018
Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding
D Zhangsun, X Zhu, Y Wu, Y Hu, Q Kaas, DJ Craik, JM McIntosh, S Luo
Journal of Biological Chemistry 290 (15), 9855-9862, 2015
252015
Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA
Y Wu, X Wu, J Yu, X Zhu, D Zhangsun, S Luo
Molecules 19 (1), 966-979, 2014
252014
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Artiklar 1–20