COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes AL Jenner, RA Aogo, S Alfonso, V Crowe, X Deng, AP Smith, PA Morel, ... PLoS pathogens 17 (7), e1009753, 2021 | 86 | 2021 |
Mathematical modelling of the interaction between cancer cells and an oncolytic virus: insights into the effects of treatment protocols AL Jenner, CO Yun, PS Kim, ACF Coster Bulletin of mathematical biology 80, 1615-1629, 2018 | 78 | 2018 |
Engineering in medicine to address the challenge of cancer drug resistance: from micro-and nanotechnologies to computational and mathematical modeling M Craig, AL Jenner, B Namgung, LP Lee, A Goldman Chemical Reviews 121 (6), 3352-3389, 2020 | 62 | 2020 |
Oncolytic virotherapy for tumours following a Gompertz growth law AL Jenner, PS Kim, F Frascoli Journal of theoretical biology 480, 129-140, 2019 | 61 | 2019 |
Iterative community-driven development of a SARS-CoV-2 tissue simulator M Getz, Y Wang, G An, M Asthana, A Becker, C Cockrell, N Collier, ... BioRxiv, 2020.04. 02.019075, 2021 | 57 | 2021 |
In silico trials predict that combination strategies for enhancing vesicular stomatitis oncolytic virus are determined by tumor aggressivity AL Jenner, T Cassidy, K Belaid, MC Bourgeois-Daigneault, M Craig Journal for immunotherapy of cancer 9 (2), e001387, 2021 | 39 | 2021 |
Treating cancerous cells with viruses: insights from a minimal model for oncolytic virotherapy AL Jenner, ACF Coster, PS Kim, F Frascoli Swinburne, 2018 | 37 | 2018 |
Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy AL Jenner, M Smalley, D Goldman, WF Goins, CS Cobbs, RB Puchalski, ... Iscience 25 (6), 2022 | 35 | 2022 |
Enhancing oncolytic virotherapy: Observations from a Voronoi Cell-Based model AL Jenner, F Frascoli, ACF Coster, PS Kim Journal of Theoretical Biology 485, 110052, 2020 | 34 | 2020 |
Leveraging computational modeling to understand infectious diseases AL Jenner, RA Aogo, CL Davis, AM Smith, M Craig Current Pathobiology Reports 8, 149-161, 2020 | 33 | 2020 |
Optimising hydrogel release profiles for viro-immunotherapy using oncolytic adenovirus expressing IL-12 and GM-CSF with immature dendritic cells AL Jenner, F Frascoli, CO Yun, PS Kim Applied Sciences 10 (8), 2872, 2020 | 27 | 2020 |
Translational approaches to treating dynamical diseases through in silico clinical trials S Alfonso, AL Jenner, M Craig Chaos: An Interdisciplinary Journal of Nonlinear Science 30 (12), 2020 | 23 | 2020 |
Modelling combined virotherapy and immunotherapy: strengthening the antitumour immune response mediated by IL-12 and GM-CSF expression AL Jenner, CO Yun, A Yoon, ACF Coster, PS Kim Letters in Biomathematics 5 (sup1), S99-S116, 2018 | 22 | 2018 |
Application of control theory in a delayed-infection and immune-evading oncolytic virotherapy T Lee, AL Jenner, PS Kim, J Lee Mathematical Biosciences and Engineering 17 (3), 2361-2383, 2020 | 16 | 2020 |
Modelling heterogeneity in viral-tumour dynamics: The effects of gene-attenuation on viral characteristics A Jenner, CO Yun, A Yoon, PS Kim, ACF Coster Journal of Theoretical Biology 454, 41-52, 2018 | 15 | 2018 |
Agent-based modelling reveals the role of the tumor microenvironment on the short-term success of combination temozolomide/immune checkpoint blockade to treat glioblastoma A Surendran, AL Jenner, E Karimi, B Fiset, DF Quail, LA Walsh, M Craig The Journal of Pharmacology and Experimental Therapeutics 387 (1), 66-77, 2023 | 14 | 2023 |
Being Bayesian in the 2020s: opportunities and challenges in the practice of modern applied Bayesian statistics JJ Bon, A Bretherton, K Buchhorn, S Cramb, C Drovandi, C Hassan, ... Philosophical Transactions of the Royal Society A 381 (2247), 20220156, 2023 | 14 | 2023 |
Calibration of Agent Based Models for Monophasic and Biphasic Tumour Growth using Approximate Bayesian Computation X Wang, AL Jenner, R Salomone, DJ Warne, C Drovandi bioRxiv, 2022.09. 13.507714, 2022 | 14* | 2022 |
Procaspase-activating compound-1 synergizes with TRAIL to induce apoptosis in established granulosa cell tumor cell line (KGN) and explanted patient granulosa cell tumor cells … P Crosley, A Farkkila, AL Jenner, C Burlot, O Cardinal, KG Potts, ... International journal of molecular sciences 22 (9), 4699, 2021 | 13 | 2021 |
Establishing combination PAC‐1 and TRAIL regimens for treating ovarian cancer based on patient‐specific pharmacokinetic profiles using in silico clinical trials O Cardinal, C Burlot, Y Fu, P Crosley, M Hitt, M Craig, AL Jenner Computational and Systems Oncology 2 (2), e1035, 2022 | 12 | 2022 |