Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations IRA Mackenzie, EH Bigio, PG Ince, F Geser, M Neumann, NJ Cairns, ... Annals of Neurology: Official Journal of the American Neurological …, 2007 | 1221 | 2007 |
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 1039 | 2015 |
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ... Nature neuroscience 15 (11), 1488-1497, 2012 | 858 | 2012 |
Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion D Sareen, JG O’Rourke, P Meera, A Muhammad, S Grant, M Simpkinson, ... Science translational medicine 5 (208), 208ra149-208ra149, 2013 | 794 | 2013 |
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial PH Gordon, DH Moore, RG Miller, JM Florence, JL Verheijde, C Doorish, ... The Lancet Neurology 6 (12), 1045-1053, 2007 | 783 | 2007 |
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ... Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013 | 688 | 2013 |
ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration JM Ravits, AR La Spada Neurology 73 (10), 805-811, 2009 | 683 | 2009 |
Controversies and priorities in amyotrophic lateral sclerosis MR Turner, O Hardiman, M Benatar, BR Brooks, A Chio, M De Carvalho, ... The Lancet Neurology 12 (3), 310-322, 2013 | 654 | 2013 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 648 | 2018 |
Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 597 | 2016 |
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 562 | 2016 |
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 514 | 2020 |
A revision of the El Escorial criteria-2015 A Ludolph, V Drory, O Hardiman, I Nakano, J Ravits, W Robberecht, ... Amyotrophic lateral sclerosis and frontotemporal degeneration 16 (5-6), 291-292, 2015 | 504 | 2015 |
A long-term follow-up study of patients with post-poliomyelitis neuromuscular symptoms MC Dalakas, G Elder, M Hallett, J Ravits, M Baker, N Papadopoulos, ... New England Journal of Medicine 314 (15), 959-963, 1986 | 476 | 1986 |
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration Z Melamed, J López-Erauskin, MW Baughn, O Zhang, K Drenner, Y Sun, ... Nature neuroscience 22 (2), 180-190, 2019 | 470 | 2019 |
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS K Meyer, L Ferraiuolo, CJ Miranda, S Likhite, S McElroy, S Renusch, ... Proceedings of the National Academy of Sciences 111 (2), 829-832, 2014 | 419 | 2014 |
Focality of upper and lower motor neuron degeneration at the clinical onset of ALS J Ravits, P Paul, C Jorg Neurology 68 (19), 1571-1575, 2007 | 384 | 2007 |
Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes PM Andersen, KB Sims, WW Xin, R Kiely, G O'Neill, J Ravits, E Pioro, ... Amyotrophic lateral sclerosis and other motor neuron disorders 4 (2), 62-73, 2003 | 383 | 2003 |
Neuropathology of amyotrophic lateral sclerosis and its variants S Saberi, JE Stauffer, DJ Schulte, J Ravits Neurologic clinics 33 (4), 855-876, 2015 | 340 | 2015 |
Clinical spectrum of amyotrophic lateral sclerosis (ALS) LI Grad, GA Rouleau, J Ravits, NR Cashman Cold Spring Harbor perspectives in medicine 7 (8), a024117, 2017 | 313 | 2017 |