| Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, PB Watkins, ... Nature genetics 27 (4), 383-391, 2001 | 2763 | 2001 |
| Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses S Teglund, C McKay, E Schuetz, JM Van Deursen, D Stravopodis, ... Cell 93 (5), 841-850, 1998 | 1550 | 1998 |
| Identification of functionally variant MDR1 alleles among European Americans and African Americans RB Kim, BF Leake, EF Choo, GK Dresser, SV Kubba, UI Schwarz, ... Clinical Pharmacology & Therapeutics 70 (2), 189-199, 2001 | 1313 | 2001 |
| Genetic contribution to variable human CYP3A-mediated metabolism JK Lamba, YS Lin, EG Schuetz, KE Thummel Advanced drug delivery reviews 54 (10), 1271-1294, 2002 | 1256 | 2002 |
| Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1199 | 2008 |
| Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. EG Schuetz, WT Beck, JD Schuetz Molecular pharmacology 49 (2), 311-318, 1996 | 669 | 1996 |
| Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. PB Watkins, SA Wrighton, EG Schuetz, DT Molowa, PS Guzelian The Journal of clinical investigation 80 (4), 1029-1036, 1987 | 624 | 1987 |
| Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix EG Schuetz, D Li, CJ Omiecinski, U Muller‐Eberhard, HK Kleinman, ... Journal of cellular physiology 134 (3), 309-323, 1988 | 584 | 1988 |
| Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism YS Lin, ALS Dowling, SD Quigley, FM Farin, J Zhang, J Lamba, ... Molecular pharmacology 62 (1), 162-172, 2002 | 575 | 2002 |
| The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ... Nature medicine 9 (2), 220-224, 2003 | 547 | 2003 |
| The xenobiotic compound 1, 4-bis [2-(3, 5-dichloropyridyloxy)] benzene is an agonist ligand for the nuclear receptor CAR I Tzameli, P Pissios, EG Schuetz, DD Moore Molecular and cellular biology, 2000 | 503 | 2000 |
| Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression V Lamba, J Lamba, K Yasuda, S Strom, J Davila, ML Hancock, ... The Journal of pharmacology and experimental therapeutics 307 (3), 906-922, 2003 | 496 | 2003 |
| Identification of an inducible form of cytochrome P-450 in human liver. PB Watkins, SA Wrighton, P Maurel, EG Schuetz, G Mendez-Picon, ... Proceedings of the National Academy of Sciences 82 (18), 6310-6314, 1985 | 480 | 1985 |
| Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450 EG Schuetz, S Strom, K Yasuda, V Lecureur, M Assem, C Brimer, ... Journal of Biological Chemistry 276 (42), 39411-39418, 2001 | 456 | 2001 |
| Transcriptional control of intestinal cytochrome P-4503A by 1α, 25-dihydroxy vitamin D3 KE Thummel, C Brimer, K Yasuda, J Thottassery, T Senn, Y Lin, ... Molecular pharmacology 60 (6), 1399-1406, 2001 | 409 | 2001 |
| Common allelic variants of cytochrome P4503A4 and their prevalence in different populations JK Lamba, YS Lin, K Thummel, A Daly, PB Watkins, S Strom, J Zhang, ... Pharmacogenetics and Genomics 12 (2), 121-132, 2002 | 405 | 2002 |
| Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p SA Wrighton, P Maurel, EG Schuetz, PB Watkins, B Young, PS Guzelian Biochemistry 24 (9), 2171-2178, 1985 | 382 | 1985 |
| The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants J Zhang, P Kuehl, ED Green, JW Touchman, PB Watkins, A Daly, SD Hall, ... Pharmacogenetics and genomics 11 (7), 555-572, 2001 | 379 | 2001 |
| Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia C Zhou, M Assem, JC Tay, PB Watkins, B Blumberg, EG Schuetz, ... The Journal of clinical investigation 116 (6), 1703-1712, 2006 | 361 | 2006 |
| Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms HX Zheng, S Webber, A Zeevi, E Schuetz, J Zhang, P Bowman, G Boyle, ... American Journal of Transplantation 3 (4), 477-483, 2003 | 354 | 2003 |
