Circulating microRNAs as stable blood-based markers for cancer detection PS Mitchell, RK Parkin, EM Kroh, BR Fritz, SK Wyman, ... Proceedings of the national academy of sciences 105 (30), 10513-10518, 2008 | 9947 | 2008 |
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor JP Coppé, CK Patil, F Rodier, YU Sun, DP Muñoz, J Goldstein, PS Nelson, ... PLoS biology 6 (12), e301, 2008 | 4280 | 2008 |
Integrative clinical genomics of advanced prostate cancer D Robinson, EM Van Allen, YM Wu, N Schultz, RJ Lonigro, JM Mosquera, ... Cell 161 (5), 1215-1228, 2015 | 3869 | 2015 |
The molecular taxonomy of primary prostate cancer A Abeshouse, J Ahn, R Akbani, A Ally, S Amin, CD Andry, M Annala, ... Cell 163 (4), 1011-1025, 2015 | 2751 | 2015 |
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer CE Barbieri, SC Baca, MS Lawrence, F Demichelis, M Blattner, ... Nature genetics 44 (6), 685-689, 2012 | 1774 | 2012 |
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth RB Montgomery, EA Mostaghel, R Vessella, DL Hess, TF Kalhorn, ... Cancer research 68 (11), 4447-4454, 2008 | 1723 | 2008 |
Inherited DNA-repair gene mutations in men with metastatic prostate cancer CC Pritchard, J Mateo, MF Walsh, N De Sarkar, W Abida, H Beltran, ... New England Journal of Medicine 375 (5), 443-453, 2016 | 1711 | 2016 |
Trial design and objectives for castration-resistant prostate cancer: updated recommendations from the Prostate Cancer Clinical Trials Working Group 3 HI Scher, MJ Morris, WM Stadler, C Higano, E Basch, K Fizazi, ... Journal of Clinical Oncology 34 (12), 1402-1418, 2016 | 1449 | 2016 |
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer S Wang, J Gao, Q Lei, N Rozengurt, C Pritchard, J Jiao, GV Thomas, G Li, ... Cancer cell 4 (3), 209-221, 2003 | 1313 | 2003 |
Genomic correlates of clinical outcome in advanced prostate cancer W Abida, J Cyrta, G Heller, D Prandi, J Armenia, I Coleman, M Cieslik, ... Proceedings of the National Academy of Sciences 116 (23), 11428-11436, 2019 | 1144 | 2019 |
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 1087 | 2015 |
Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion WP Harris, EA Mostaghel, PS Nelson, B Montgomery Nature clinical practice Urology 6 (2), 76-85, 2009 | 1040 | 2009 |
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant S Sun, CCT Sprenger, RL Vessella, K Haugk, K Soriano, EA Mostaghel, ... The Journal of clinical investigation 120 (8), 2715-2730, 2010 | 894 | 2010 |
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B Y Sun, J Campisi, C Higano, TM Beer, P Porter, I Coleman, L True, ... Nature medicine 18 (9), 1359-1368, 2012 | 879 | 2012 |
The long tail of oncogenic drivers in prostate cancer J Armenia, SAM Wankowicz, D Liu, J Gao, R Kundra, E Reznik, ... Nature genetics 50 (5), 645-651, 2018 | 794 | 2018 |
Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer A Kumar, I Coleman, C Morrissey, X Zhang, LD True, R Gulati, R Etzioni, ... Nature medicine 22 (4), 369-378, 2016 | 731 | 2016 |
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants EA Mostaghel, BT Marck, SR Plymate, RL Vessella, S Balk, ... Clinical cancer research 17 (18), 5913-5925, 2011 | 701 | 2011 |
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2 B Lin, C Ferguson, JT White, S Wang, R Vessella, LD True, L Hood, ... Cancer research 59 (17), 4180-4184, 1999 | 684 | 1999 |
Comparative hybridization of an array of 21 500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas M Schummer, WLV Ng, RE Bumgarner, PS Nelson, B Schummer, ... Gene 238 (2), 375-385, 1999 | 667 | 1999 |
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer R Hu, C Lu, EA Mostaghel, S Yegnasubramanian, M Gurel, C Tannahill, ... Cancer research 72 (14), 3457-3462, 2012 | 658 | 2012 |