Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy CG Faber, JGJ Hoeijmakers, HS Ahn, X Cheng, C Han, JS Choi, ... Annals of neurology 71 (1), 26-39, 2012 | 603 | 2012 |
Gain-of-function mutations in sodium channel NaV1.9 in painful neuropathy J Huang, C Han, M Estacion, D Vasylyev, JGJ Hoeijmakers, MM Gerrits, ... Brain 137 (6), 1627-1642, 2014 | 317 | 2014 |
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release PA Verhoef, M Estacion, W Schilling, GR Dubyak The Journal of Immunology 170 (11), 5728-5738, 2003 | 235 | 2003 |
Safety and efficacy of a Nav1. 7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial JM Zakrzewska, J Palmer, V Morisset, GMP Giblin, M Obermann, DA Ettlin, ... The Lancet Neurology 16 (4), 291-300, 2017 | 205 | 2017 |
NaV1. 7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and … M Estacion, SD Dib-Hajj, PJ Benke, RHM Te Morsche, EM Eastman, ... Journal of Neuroscience 28 (43), 11079-11088, 2008 | 192 | 2008 |
Subtype-selective small molecule inhibitors reveal a fundamental role for Nav1. 7 in nociceptor electrogenesis, axonal conduction and presynaptic release AJ Alexandrou, AR Brown, ML Chapman, M Estacion, J Turner, MA Mis, ... PloS one 11 (4), e0152405, 2016 | 184 | 2016 |
Identification and localization of TRPC channels in the rat kidney M Goel, WG Sinkins, CD Zuo, M Estacion, WP Schilling American Journal of Physiology-Renal Physiology 290 (5), F1241-F1252, 2006 | 177 | 2006 |
A novel Nav1.7 mutation producing carbamazepine‐responsive erythromelalgia TZ Fischer, ES Gilmore, M Estacion, E Eastman, S Taylor, M Melanson, ... Annals of Neurology: Official Journal of the American Neurological …, 2009 | 166 | 2009 |
Regulation of Drosophila transient receptor potential‐like (TrpL) channels by phospholipase C‐dependent mechanisms M Estacion, WG Sinkins, WP Schilling The Journal of Physiology 530 (1), 1-19, 2001 | 164 | 2001 |
Paroxysmal Extreme Pain Disorder M1627K Mutation in Human Nav1.7 Renders DRG Neurons Hyperexcitable SD Dib-Hajj, M Estacion, BW Jarecki, L Tyrrell, TZ Fischer, M Lawden, ... Molecular pain 4, 1744-8069-4-37, 2008 | 152 | 2008 |
Voltage-clamp and current-clamp recordings from mammalian DRG neurons TR Cummins, AM Rush, M Estacion, SD Dib-Hajj, SG Waxman Nature protocols 4 (8), 1103-1112, 2009 | 140 | 2009 |
Human TRPC6 expressed in HEK 293 cells forms non‐selective cation channels with limited Ca2+ permeability M Estacion, WG Sinkins, SW Jones, MAB Applegate, WP Schilling The Journal of physiology 572 (2), 359-377, 2006 | 138 | 2006 |
Association of immunophilins with mammalian TRPC channels WG Sinkins, M Goel, M Estacion, WP Schilling Journal of Biological Chemistry 279 (33), 34521-34529, 2004 | 136 | 2004 |
Activation of human TRPC6 channels by receptor stimulation M Estacion, S Li, WG Sinkins, M Gosling, P Bahra, C Poll, J Westwick, ... Journal of Biological Chemistry 279 (21), 22047-22056, 2004 | 132 | 2004 |
A novel de novo mutation of SCN8A (Nav1. 6) with enhanced channel activation in a child with epileptic encephalopathy M Estacion, JE O'Brien, A Conravey, MF Hammer, SG Waxman, ... Neurobiology of disease 69, 117-123, 2014 | 130 | 2014 |
A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1. 3 and induces hyperexcitability in hippocampal neurons M Estacion, A Gasser, SD Dib-Hajj, SG Waxman Experimental neurology 224 (2), 362-368, 2010 | 128 | 2010 |
A sodium channel gene SCN9A polymorphism that increases nociceptor excitability M Estacion, TP Harty, JS Choi, L Tyrrell, SD Dib‐Hajj, SG Waxman Annals of Neurology: Official Journal of the American Neurological …, 2009 | 126 | 2009 |
Functional expression of TrpC1: a human homologue of the Drosophila Trp channel WG SINKINS, M ESTACION, WP SCHILLING Biochemical Journal 331 (1), 331-339, 1998 | 126 | 1998 |
Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons C Han, M Estacion, J Huang, D Vasylyev, P Zhao, SD Dib-Hajj, ... Journal of neurophysiology 113 (9), 3172-3185, 2015 | 125 | 2015 |
Intra- and Interfamily Phenotypic Diversity in Pain Syndromes Associated with a Gain-of-Function Variant of NaV1.7 M Estacion, C Han, JS Choi, JGJ Hoeijmakers, G Lauria, JPH Drenth, ... Molecular pain 7, 1744-8069-7-92, 2011 | 123 | 2011 |