Antibodies against immune checkpoint molecules restore functions of tumor-infiltrating T cells in hepatocellular carcinomas G Zhou, D Sprengers, PPC Boor, M Doukas, H Schutz, S Mancham, ... Gastroenterology 153 (4), 1107-1119. e10, 2017 | 408 | 2017 |
Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B RG van der Molen, D Sprengers, RS Binda, EC de Jong, HGM Niesters, ... Hepatology 40 (3), 738-746, 2004 | 408 | 2004 |
Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment LA Dieleman, MS Goerres, A Arends, D Sprengers, C Torrice, F Hoentjen, ... Gut 52 (3), 370-376, 2003 | 291 | 2003 |
Activated tumor‐infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer A Pedroza‐Gonzalez, C Verhoef, JNM Ijzermans, MP Peppelenbosch, ... Hepatology 57 (1), 183-194, 2013 | 213 | 2013 |
Modeling rotavirus infection and antiviral therapy using primary intestinal organoids Y Yin, M Bijvelds, W Dang, L Xu, AA van der Eijk, K Knipping, N Tuysuz, ... Antiviral research 123, 120-131, 2015 | 199 | 2015 |
TIGIT, the next step towards successful combination immune checkpoint therapy in cancer Z Ge, MP Peppelenbosch, D Sprengers, J Kwekkeboom Frontiers in immunology 12, 699895, 2021 | 190 | 2021 |
Surveillance for hepatocellular carcinoma is associated with increased survival: results from a large cohort in the Netherlands S van Meer, RA de Man, MJ Coenraad, D Sprengers, KMJ van Nieuwkerk, ... Journal of hepatology 63 (5), 1156-1163, 2015 | 169 | 2015 |
Cancer-associated fibroblasts provide a stromal niche for liver cancer organoids that confers trophic effects and therapy resistance J Liu, P Li, L Wang, M Li, Z Ge, L Noordam, R Lieshout, MMA Verstegen, ... Cellular and molecular gastroenterology and hepatology 11 (2), 407-431, 2021 | 159 | 2021 |
Flares in chronic hepatitis B patients induced by the host or the virus? Relation to treatment response during Peg-interferon α-2b therapy HJ Flink, D Sprengers, BE Hansen, M van Zonneveld, RA De Man, ... Gut 54 (11), 1604-1609, 2005 | 147 | 2005 |
PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma K Sideras, K Biermann, J Verheij, BR Takkenberg, S Mancham, ... Oncoimmunology 6 (2), e1273309, 2017 | 145 | 2017 |
Hepatitis E virus infects neurons and brains X Zhou, F Huang, L Xu, Z Lin, FMS de Vrij, AC Ayo-Martin, ... The Journal of infectious diseases 215 (8), 1197-1206, 2017 | 129 | 2017 |
Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors A Pedroza-Gonzalez, G Zhou, E Vargas-Mendez, PPC Boor, S Mancham, ... Oncoimmunology 4 (6), e1008355, 2015 | 126 | 2015 |
Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules G Zhou, D Sprengers, S Mancham, R Erkens, PPC Boor, AA van Beek, ... Journal of hepatology 71 (4), 753-762, 2019 | 123 | 2019 |
Multiple biopsy passes and the risk of complications of percutaneous liver biopsy H Chi, BE Hansen, WY Tang, JNL Schouten, D Sprengers, P Taimr, ... European journal of gastroenterology & hepatology 29 (1), 36-41, 2017 | 101 | 2017 |
α-Galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial AM Woltman, MJ Ter Borg, RS Binda, D Sprengers, BME von Blomberg, ... Antiviral therapy 14 (6), 809-818, 2009 | 101 | 2009 |
Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV RG van der Molen, D Sprengers, PJ Biesta, JG Kusters, HLA Janssen Hepatology 44 (4), 907-914, 2006 | 101 | 2006 |
Mitochondrial fusion via OPA1 and MFN1 supports liver tumor cell metabolism and growth M Li, L Wang, Y Wang, S Zhang, G Zhou, R Lieshout, B Ma, J Liu, C Qu, ... Cells 9 (1), 121, 2020 | 97 | 2020 |
Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis E virus replication Y Wang, W Wang, L Xu, X Zhou, E Shokrollahi, K Felczak, ... Antimicrobial agents and chemotherapy 60 (5), 2834-2848, 2016 | 85 | 2016 |
Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV W Wang, L Xu, JH Brandsma, Y Wang, MS Hakim, X Zhou, Y Yin, ... Scientific reports 6 (1), 25482, 2016 | 79 | 2016 |
SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma PY Hernanda, K Chen, AM Das, K Sideras, W Wang, J Li, W Cao, ... Oncogene 34 (39), 5055-5068, 2015 | 79 | 2015 |