CODA: quantitative 3D reconstruction of large tissues at cellular resolution AL Kiemen, AM Braxton, MP Grahn, KS Han, JM Babu, R Reichel, ... Nature Methods 19 (11), 1490-1499, 2022 | 108 | 2022 |
Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion SM Hong, DJ Jung, A Kiemen, MM Gaida, T Yoshizawa, AM Braxton, ... Modern Pathology 33 (4), 639-647, 2020 | 57 | 2020 |
In situ characterization of the 3D microanatomy of the pancreas and pancreatic cancer at single cell resolution A Kiemen, AM Braxton, MP Grahn, KS Han, JM Babu, R Reichel, F Amoa, ... BioRxiv, 2020.12. 08.416909, 2020 | 44 | 2020 |
3D genomic mapping reveals multifocality of human pancreatic precancers AM Braxton, AL Kiemen, MP Grahn, A Forjaz, J Parksong, J Mahesh Babu, ... Nature 629 (8012), 679-687, 2024 | 35 | 2024 |
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces A Deshpande, M Loth, DN Sidiropoulos, S Zhang, L Yuan, ATF Bell, ... Cell systems 14 (4), 285-301. e4, 2023 | 29 | 2023 |
Three‐dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding T Yoshizawa, SM Hong, DJ Jung, M Noë, A Kiemen, PH Wu, D Wirtz, ... The Journal of pathology 251 (4), 400-410, 2020 | 24 | 2020 |
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth Y Xue, C Lyu, A Taylor, A Van Ee, A Kiemen, YG Choi, N Khavanian, ... Science Advances 8 (17), eabl8698, 2022 | 21 | 2022 |
Tissue clearing and 3D reconstruction of digitized, serially sectioned slides provide novel insights into pancreatic cancer AL Kiemen, AI Damanakis, AM Braxton, J He, D Laheru, EK Fishman, ... Med 4 (2), 75-91, 2023 | 20 | 2023 |
Engineered bispecific antibodies targeting the interleukin-6 and-8 receptors potently inhibit cancer cell migration and tumor metastasis H Yang, MN Karl, W Wang, B Starich, H Tan, A Kiemen, AB Pucsek, ... Molecular Therapy 30 (11), 3430-3449, 2022 | 19 | 2022 |
Deep learning identification of stiffness markers in breast cancer A Sneider, A Kiemen, JH Kim, PH Wu, M Habibi, M White, JM Phillip, L Gu, ... Biomaterials 285, 121540, 2022 | 18 | 2022 |
Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models AE de Groot, KV Myers, TEG Krueger, AL Kiemen, NH Nagy, A Brame, ... The Prostate 81 (10), 629-647, 2021 | 16 | 2021 |
PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration ATF Bell, JT Mitchell, AL Kiemen, M Lyman, K Fujikura, JW Lee, E Coyne, ... Cell Systems 15 (8), 753-769. e5, 2024 | 15 | 2024 |
Multi-compartment tumor organoids MH Lee, GC Russo, YS Rahmanto, W Du, AJ Crawford, PH Wu, D Gilkes, ... Materials Today 61, 104-116, 2022 | 15 | 2022 |
Digitize your Biology! Modeling multicellular systems through interpretable cell behavior JAI Johnson, GL Stein-O’Brien, M Booth, R Heiland, F Kurtoglu, ... bioRxiv, 2023 | 11 | 2023 |
Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions AM Braxton, AL Kiemen, MP Grahn, A Forjaz, JM Babu, L Zheng, L Jiang, ... bioRxiv, 2023 | 11 | 2023 |
Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer AL Kiemen, YG Choi, AM Braxton, C Almagro Perez, S Graham, ... Histopathology 82 (3), 504-506, 2023 | 9 | 2023 |
Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues A Forjaz, E Vaz, VM Romero, S Joshi, AM Braxton, AC Jiang, K Fujikura, ... Biorxiv, 2023.12. 04.569986, 2024 | 8 | 2024 |
Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors AC Johnston, GM Alicea, CC Lee, PV Patel, EA Hanna, E Vaz, A Forjaz, ... BioRxiv, 2023.12. 13.571595, 2024 | 7 | 2024 |
Precision-engineered biomimetics: the human fallopian tube AJ Crawford, A Forjaz, I Bhorkar, T Roy, D Schell, V Queiroga, K Ren, ... BioRxiv, 2023.06. 06.543923, 2023 | 6 | 2023 |
Spatial transcriptomics of FFPE pancreatic intraepithelial neoplasias reveals cellular and molecular alterations of progression to pancreatic ductal carcinoma AT Bell, JT Mitchell, AL Kiemen, K Fujikura, H Fedor, B Gambichler, ... Biorxiv, 2022 | 6 | 2022 |