| Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability P Brouwer, T Caniels, K van Straten, J Snitselaar, Y Aldon, S Bangaru, ... Science 369 (6504), 643-650, 2020 | 1263 | 2020 |
| Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ... Nature 515 (7525), 138-142, 2014 | 520 | 2014 |
| Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers C Blattner, JH Lee, K Sliepen, R Derking, E Falkowska, AT de la Peña, ... Immunity 40 (5), 669-680, 2014 | 404 | 2014 |
| Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy G Schreibelt, J Tel, KH Sliepen, D Benitez-Ribas, CG Figdor, GJ Adema, ... Cancer immunology, immunotherapy 59, 1573-1582, 2010 | 358 | 2010 |
| Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity K Sliepen, G Ozorowski, JA Burger, T van Montfort, M Stunnenberg, ... Retrovirology 12, 1-5, 2015 | 212 | 2015 |
| Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, ... Nature Communications 10 (1), 4272, 2019 | 183 | 2019 |
| Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity JK Hu, JC Crampton, A Cupo, T Ketas, MJ van Gils, K Sliepen, ... Journal of virology 89 (20), 10383-10398, 2015 | 180 | 2015 |
| Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection PJM Brouwer, M Brinkkemper, P Maisonnasse, N Dereuddre-Bosquet, ... Cell 184 (5), 1188-1200. e19, 2021 | 176 | 2021 |
| Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ... Journal of Experimental Medicine 214 (9), 2573-2590, 2017 | 169 | 2017 |
| Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization AT de la Peña, JP Julien, SW de Taeye, F Garces, M Guttman, ... Cell Reports 20 (8), 1805-1817, 2017 | 162 | 2017 |
| Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence K Sliepen, BW Han, I Bontjer, P Mooij, F Garces, AJ Behrens, ... Nature communications 10 (1), 2355, 2019 | 146 | 2019 |
| Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer R Derking, G Ozorowski, K Sliepen, A Yasmeen, A Cupo, JL Torres, ... PLoS pathogens 11 (3), e1004767-e1004767, 2015 | 118 | 2015 |
| Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike JH Lee, DP Leaman, AS Kim, A Torrents de La Peña, K Sliepen, ... Nature communications 6 (1), 8167, 2015 | 103 | 2015 |
| Immunogenicity in rabbits of HIV-1 SOSIP trimers from clades A, B, and C, given individually, sequentially, or in combination A Torrents de la Peña, SW de Taeye, K Sliepen, CC LaBranche, ... Journal of Virology 92 (8), 10.1128/jvi. 01957-17, 2018 | 86 | 2018 |
| Immunosilencing a highly immunogenic protein trimerization domain K Sliepen, T van Montfort, M Melchers, G Isik, RW Sanders Journal of Biological Chemistry 290 (12), 7436-7442, 2015 | 86 | 2015 |
| Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer L Kong, A Torrents de la Peña, MC Deller, F Garces, K Sliepen, Y Hua, ... Biological Crystallography 71 (10), 2099-2108, 2015 | 70 | 2015 |
| Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers K Sliepen, M Medina-Ramírez, A Yasmeen, JP Moore, PJ Klasse, ... Virology 486, 116-120, 2015 | 57 | 2015 |
| HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies K Sliepen, RW Sanders Expert review of vaccines 15 (3), 349-365, 2016 | 56 | 2016 |
| Structure of the hepatitis C virus E1E2 glycoprotein complex A Torrents de la Peña, K Sliepen, L Eshun-Wilson, ML Newby, JD Allen, ... Science 378 (6617), 263-269, 2022 | 55 | 2022 |
| Nanoparticle Vaccines for Inducing HIV-1 Neutralizing Antibodies M Brinkkemper, K Sliepen Vaccines 7 (3), 76, 2019 | 53 | 2019 |
