Прати
Colin H Lipper
Colin H Lipper
Postdoctoral Fellow, Harvard Medical School
Верификована је имејл адреса на hms.harvard.edu
Наслов
Навело
Навело
Година
Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease
S Tamir, ML Paddock, M Darash-Yahana-Baram, SH Holt, YS Sohn, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (6), 1294-1315, 2015
1792015
Redox-dependent gating of VDAC by mitoNEET
CH Lipper, JT Stofleth, F Bai, YS Sohn, S Roy, R Mittler, R Nechushtai, ...
Proceedings of the National Academy of Sciences 116 (40), 19924-19929, 2019
1142019
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer
F Bai, F Morcos, YS Sohn, M Darash-Yahana, CO Rezende, CH Lipper, ...
Proceedings of the National Academy of Sciences 112 (12), 3698-3703, 2015
932015
Cancer-related NEET proteins transfer 2Fe-2S clusters to anamorsin, a protein required for cytosolic iron-sulfur cluster biogenesis
CH Lipper, ML Paddock, JN Onuchic, R Mittler, R Nechushtai, ...
PLoS One 10 (10), e0139699, 2015
852015
Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells
CH Lipper, O Karmi, YS Sohn, M Darash-Yahana, H Lammert, L Song, ...
Proceedings of the National Academy of Sciences 115 (2), 272-277, 2018
812018
Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1
S Tamir, S Rotem-Bamberger, C Katz, F Morcos, KL Hailey, JA Zuris, ...
Proceedings of the National Academy of Sciences 111 (14), 5177-5182, 2014
622014
Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs
S Tamir, JA Zuris, L Agranat, CH Lipper, AR Conlan, D Michaeli, Y Harir, ...
PLoS One 8 (5), e61202, 2013
572013
A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties
S Tamir, Y Eisenberg-Domovich, AR Conlan, JT Stofleth, CH Lipper, ...
Biological Crystallography 70 (6), 1572-1578, 2014
402014
Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site
CH Lipper, KH Gabriel, TCM Seegar, KL Dürr, MG Tomlinson, ...
Structure 30 (2), 206-214. e4, 2022
232022
Structural basis for membrane-proximal proteolysis of substrates by ADAM10
CH Lipper, ED Egan, KH Gabriel, SC Blacklow
Cell 186 (17), 3632-3641. e10, 2023
212023
Molecular dynamics simulations of the [2Fe–2S] cluster-binding domain of NEET proteins reveal key molecular determinants that induce their cluster transfer/release
L Pesce, V Calandrini, H Marjault, CH Lipper, G Rossetti, R Mittler, ...
The Journal of Physical Chemistry B 121 (47), 10648-10656, 2017
212017
IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation
L Pan, ME Lemieux, T Thomas, JM Rogers, CH Lipper, W Lee, C Johnson, ...
elife 9, e58081, 2020
192020
Design of high-affinity metal-controlled protein dimers
B Maniaci, CH Lipper, DL Anipindi, H Erlandsen, JL Cole, B Stec, ...
Biochemistry 58 (17), 2199-2207, 2019
112019
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling
DTD Jones, AN Dates, SD Rawson, MM Burruss, CH Lipper, SC Blacklow
Nature Communications 14 (1), 2490, 2023
62023
Structural basis for selective proteolysis of ADAM10 substrates at membrane-proximal sites
CH Lipper, ED Egan, KH Gabriel, SC Blacklow
BioRxiv, 2022.10. 22.513345, 2022
42022
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues
KH Kock, PK Kimes, SS Gisselbrecht, S Inukai, SK Phanor, JT Anderson, ...
Nature Communications 15 (1), 3110, 2024
32024
DNA binding analysis of rare variants in homeodomains reveals novel homeodomain specificity-determining residues
KH Kock, PK Kimes, SS Gisselbrecht, S Inukai, SK Phanor, JT Anderson, ...
bioRxiv, 2023.06. 16.545320, 2023
12023
Tethered agonist activated ADGRF1 structure reveals molecular preference for Gαq signalling
DTD Jones, AN Dates, SD Rawson, MM Burruss, CH Lipper, SC Blacklow
bioRxiv, 2022.09. 09.507336, 2022
2022
Biochemical and Structural Characterization of the NEET Protein Family and their Role in Iron Homeostasis and Disease
CH Lipper
University of California, San Diego, 2017
2017
The NEET Proteins Mediate Iron-Sulfur Cluster Transport from the Mitochondria to Cytosolic Proteins
CH Lipper, ML Paddock, R Nechushtai, PA Jennings
Biophysical Journal 110 (3), 549a, 2016
2016
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Чланци 1–20