Чланци са овлашћеним јавним приступом - Jamie A. MorocoСазнајте више
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Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice
R Mourtada, HD Herce, DJ Yin, JA Moroco, TE Wales, JR Engen, ...
Nature biotechnology 37 (10), 1186-1197, 2019
Овлашћења: US National Institutes of Health, Canadian Institutes of Health Research
Доступно негде: 18
Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways
J Lee, EW Su, C Zhu, S Hainline, J Phuah, JA Moroco, TE Smithgall, ...
Molecular and cellular biology, 2011
Овлашћења: US National Institutes of Health
Differential sensitivity of Src-family kinases to activation by SH3 domain displacement
JA Moroco, JK Craigo, RE Iacob, TE Wales, JR Engen, TE Smithgall
PloS one 9 (8), e105629, 2014
Овлашћења: US National Institutes of Health
Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism
JJ Alvarado, L Betts, JA Moroco, TE Smithgall, JI Yeh
Journal of Biological Chemistry 285 (46), 35455-35461, 2010
Овлашћења: US National Institutes of Health
Discovery of a first-in-class inhibitor of the PRMT5–substrate adaptor interaction
DC McKinney, BJ McMillan, MJ Ranaghan, JA Moroco, M Brousseau, ...
Journal of medicinal chemistry 64 (15), 11148-11168, 2021
Овлашћења: US National Institutes of Health
Allosteric control of Ubp6 and the proteasome via a bidirectional switch
KYS Hung, S Klumpe, MR Eisele, S Elsasser, G Tian, S Sun, JA Moroco, ...
Nature communications 13 (1), 838, 2022
Овлашћења: US National Institutes of Health, German Research Foundation
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state
PG Miller, M Sathappa, JA Moroco, W Jiang, Y Qian, S Iqbal, Q Guo, ...
Nature Communications 13 (1), 3778, 2022
Овлашћења: US National Institutes of Health, Howard Hughes Medical Institute
Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding
JR Kardon, JA Moroco, JR Engen, TA Baker
Elife 9, e54387, 2020
Овлашћења: US National Institutes of Health, Howard Hughes Medical Institute
The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulation
K Shen, JA Moroco, RK Patel, H Shi, JR Engen, HR Dorman, TE Smithgall
Science signaling 11 (553), eaat5916, 2018
Овлашћења: US National Institutes of Health
HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck
T Pene-Dumitrescu, ST Shu, TE Wales, JJ Alvarado, H Shi, P Narute, ...
BMC Chemical Biology 12, 1-12, 2012
Овлашћења: US National Institutes of Health
Multimodal small-molecule screening for human prion protein binders
AG Reidenbach, MF Mesleh, D Casalena, SM Vallabh, JL Dahlin, ...
Journal of Biological Chemistry 295 (39), 13516-13531, 2020
Овлашћења: US National Institutes of Health
Replication in bioanalytical studies with HDX MS: aim as high as possible
JA Moroco, JR Engen
Bioanalysis 7 (9), 1065-1067, 2015
Овлашћења: US National Institutes of Health
Remodeling of HIV-1 Nef structure by Src-family kinase binding
JA Moroco, JJ Alvarado, RP Staudt, H Shi, TE Wales, TE Smithgall, ...
Journal of molecular biology 430 (3), 310-321, 2018
Овлашћења: US National Institutes of Health
A Discovery Strategy for Selective Inhibitors of c‐Src in Complex with the Focal Adhesion Kinase SH3/SH2‐binding Region
JA Moroco, MP Baumgartner, HL Rust, HG Choi, W Hur, NS Gray, ...
Chemical biology & drug design 86 (2), 144-155, 2015
Овлашћења: US National Institutes of Health
Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35
TC Atack, DD Raymond, CA Blomquist, CF Pasaje, PR McCarren, ...
ACS Medicinal Chemistry Letters 11 (11), 2131-2138, 2020
Овлашћења: Bill & Melinda Gates Foundation, US National Institutes of Health
Design of stapled antimicrobial peptides that overcome antibiotic resistance and in vivo toxicity
R Mourtada, HD Herce, DJ Yin, JA Moroco, TE Wales, JR Engen, ...
Nature biotechnology 37 (10), 1186, 2019
Овлашћења: US National Institutes of Health, Canadian Institutes of Health Research
ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr
S Du, JJ Alvarado, TE Wales, JA Moroco, JR Engen, TE Smithgall
Structure 30 (11), 1508-1517. e3, 2022
Овлашћења: US Department of Energy, US National Institutes of Health
Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency
MS Prew, CM Camara, T Botzanowski, JA Moroco, NB Bloch, HR Levy, ...
Nature Communications 13 (1), 3669, 2022
Овлашћења: US National Science Foundation, US National Institutes of Health
Mitochondrial ClpX activates an essential metabolic enzyme through partial unfolding
JR Kardon, JA Moroco, JR Engen, TA Baker
bioRxiv, 327056, 2018
Овлашћења: US National Institutes of Health, Howard Hughes Medical Institute
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