Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-β, and Bcl-2 M Høyer-Hansen, L Bastholm, P Szyniarowski, M Campanella, ... Molecular cell 25 (2), 193-205, 2007 | 1267 | 2007 |
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization J Nylandsted, M Gyrd-Hansen, A Danielewicz, N Fehrenbacher, ... The Journal of experimental medicine 200 (4), 425-435, 2004 | 701 | 2004 |
Lysosomes as targets for cancer therapy N Fehrenbacher, M Jäättelä Cancer research 65 (8), 2993-2995, 2005 | 378 | 2005 |
Effective tumor cell death by σ-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress MS Ostenfeld, N Fehrenbacher, M Høyer-Hansen, C Thomsen, T Farkas, ... Cancer research 65 (19), 8975-8983, 2005 | 293 | 2005 |
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2 N Fehrenbacher, L Bastholm, T Kirkegaard-Sørensen, B Rafn, T Bøttzauw, ... Cancer research 68 (16), 6623-6633, 2008 | 268 | 2008 |
Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens CH Villa, T Dao, I Ahearn, N Fehrenbacher, E Casey, DA Rey, ... ACS nano 5 (7), 5300-5311, 2011 | 255 | 2011 |
Ras/MAPK signaling from endomembranes N Fehrenbacher, D Bar-Sagi, M Philips Molecular oncology 3 (4), 297-307, 2009 | 185 | 2009 |
Sensitization to the lysosomal cell death pathway upon immortalization and transformation N Fehrenbacher, M Gyrd-Hansen, B Poulsen, U Felbor, T Kallunki, ... Cancer research 64 (15), 5301-5310, 2004 | 183 | 2004 |
Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation MS Ostenfeld, M Høyer-Hansen, L Bastholm, N Fehrenbacher, OD Olsen, ... Autophagy 4 (4), 487-499, 2008 | 181 | 2008 |
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression B Rafn, CF Nielsen, SH Andersen, P Szyniarowski, E Corcelle-Termeau, ... Molecular cell 45 (6), 764-776, 2012 | 140 | 2012 |
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9 M Gyrd-Hansen, T Farkas, N Fehrenbacher, L Bastholm, M Høyer-Hansen, ... Molecular and cellular biology 26 (21), 7880-7891, 2006 | 128 | 2006 |
FKBP12 binds to acylated H-ras and promotes depalmitoylation IM Ahearn, FD Tsai, M Zhou, BC Jennings, M Ahmed, N Fehrenbacher, ... Molecular cell 41 (2), 173-185, 2011 | 121 | 2011 |
GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase S Kuchay, H Wang, A Marzio, K Jain, H Homer, N Fehrenbacher, ... Nature structural & molecular biology 26 (7), 628-636, 2019 | 90 | 2019 |
Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors PJ Sung, FD Tsai, H Vais, H Court, J Yang, N Fehrenbacher, JK Foskett, ... Proceedings of the National Academy of Sciences 110 (51), 20593-20598, 2013 | 79 | 2013 |
JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways N Dietrich, J Thastrup, C Holmberg, M Gyrd-Hansen, N Fehrenbacher, ... Cell Death & Differentiation 11 (3), 301-313, 2004 | 79 | 2004 |
The G protein–coupled receptor GPR31 promotes membrane association of KRAS N Fehrenbacher, I Tojal da Silva, C Ramirez, Y Zhou, KJ Cho, S Kuchay, ... Journal of Cell Biology 216 (8), 2329-2338, 2017 | 28 | 2017 |
Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association M Zhou, L Kuruvilla, X Shi, S Viviano, IM Ahearn, CR Amendola, W Su, ... Proceedings of the National Academy of Sciences 117 (50), 31914-31922, 2020 | 11 | 2020 |
Intracellular signaling: peripatetic Ras N Fehrenbacher, M Philips Current Biology 19 (11), R454-R457, 2009 | 10 | 2009 |
Targeting RAS–will GPR31 deliver us a new path forward? N Fehrenbacher, MR Philips Molecular & cellular oncology 4 (6), e1359228, 2017 | 4 | 2017 |
Correction for Gyrd-Hansen et al.,“Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9” M Gyrd-Hansen, T Farkas, N Fehrenbacher, L Bastholm, M Høyer-Hansen, ... Molecular and Cellular Biology 38 (2), e00563-17, 2017 | | 2017 |