Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans Y Wang, KSL Lam, EW Kraegen, G Sweeney, J Zhang, AWK Tso, ... Clinical chemistry 53 (1), 34-41, 2007 | 755 | 2007 |
Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice Z Lin, H Tian, KSL Lam, S Lin, RCL Hoo, M Konishi, N Itoh, Y Wang, ... Cell metabolism 17 (5), 779-789, 2013 | 737 | 2013 |
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes A Xu, KW Chan, RLC Hoo, Y Wang, KCB Tan, J Zhang, B Chen, MC Lam, ... Journal of Biological Chemistry 280 (18), 18073-18080, 2005 | 574 | 2005 |
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, ... The journal of clinical investigation 129 (2), 834-849, 2019 | 405 | 2019 |
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice A Xu, MC Lam, KW Chan, Y Wang, J Zhang, RLC Hoo, JY Xu, B Chen, ... Proceedings of the National Academy of Sciences 102 (17), 6086-6091, 2005 | 396 | 2005 |
Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight … Y Wang, KSL Lam, L Chan, KW Chan, JBB Lam, MC Lam, RCL Hoo, ... Journal of Biological Chemistry 281 (24), 16391-16400, 2006 | 340 | 2006 |
Adiponectin modulates the glycogen synthase kinase-3β/β-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice Y Wang, JB Lam, KSL Lam, J Liu, MC Lam, RLC Hoo, D Wu, GJS Cooper, ... Cancer research 66 (23), 11462-11470, 2006 | 333 | 2006 |
Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin SY Yau, A Li, RLC Hoo, YP Ching, BR Christie, TMC Lee, A Xu, KF So Proceedings of the National Academy of Sciences 111 (44), 15810-15815, 2014 | 317 | 2014 |
Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes B Chen, KSL Lam, Y Wang, D Wu, MC Lam, J Shen, L Wong, RLC Hoo, ... Biochemical and biophysical research communications 341 (2), 549-556, 2006 | 308 | 2006 |
Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice RCL Ng, OY Cheng, M Jian, JSC Kwan, PWL Ho, KKY Cheng, ... Molecular neurodegeneration 11, 1-16, 2016 | 172 | 2016 |
Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes W Chen, RL Hoo, M Konishi, N Itoh, P Lee, H Ye, KS Lam, A Xu Journal of Biological Chemistry 286 (40), 34559-34566, 2011 | 162 | 2011 |
Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway J Chang, Y Li, Y Huang, KSL Lam, RLC Hoo, WT Wong, KKY Cheng, ... Diabetes 59 (11), 2949-2959, 2010 | 149 | 2010 |
Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice WT Wong, XY Tian, A Xu, J Yu, CW Lau, RLC Hoo, Y Wang, VWY Lee, ... Cell metabolism 14 (1), 104-115, 2011 | 138 | 2011 |
Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice A Xu, H Wang, RLC Hoo, G Sweeney, PM Vanhoutte, Y Wang, D Wu, ... Endocrinology 150 (2), 625-633, 2009 | 131 | 2009 |
The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti … RLC Hoo, JYL Wong, CF Qiao, A Xu, HX Xu, KSL Lam Nutrition & Metabolism 7, 1-12, 2010 | 125 | 2010 |
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury M Zhou, A Xu, PKH Tam, KSL Lam, L Chan, RLC Hoo, J Liu, KHM Chow, ... Hepatology 48 (4), 1087-1096, 2008 | 122 | 2008 |
Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes KCB Tan, WS Chow, AWK Tso, A Xu, HF Tse, RLC Hoo, DJ Betteridge, ... Diabetologia 50, 1819-1825, 2007 | 111 | 2007 |
CRAF methylation by PRMT6 regulates aerobic glycolysis–driven hepatocarcinogenesis via ERK‐dependent PKM2 nuclear relocalization and activation TL Wong, KY Ng, KV Tan, LH Chan, L Zhou, N Che, RLC Hoo, TK Lee, ... Hepatology 71 (4), 1279-1296, 2020 | 107 | 2020 |
A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes L Shu, RLC Hoo, X Wu, Y Pan, IPC Lee, LY Cheong, SR Bornstein, ... Nature communications 8 (1), 14147, 2017 | 97 | 2017 |
The novel perspectives of adipokines on brain health TH Lee, KK Cheng, RL Hoo, PM Siu, S Yau International journal of molecular sciences 20 (22), 5638, 2019 | 90 | 2019 |