A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster JFW Chan, S Yuan, KH Kok, KKW To, H Chu, J Yang, F Xing, J Liu, ... The lancet 395 (10223), 514-523, 2020 | 12230 | 2020 |
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study KKW To, OTY Tsang, WS Leung, AR Tam, TC Wu, DC Lung, CCY Yip, ... The Lancet infectious diseases 20 (5), 565-574, 2020 | 4070 | 2020 |
Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in a golden Syrian hamster model: implications for disease pathogenesis and … JFW Chan, AJ Zhang, S Yuan, VKM Poon, CCS Chan, ACY Lee, ... Clinical infectious diseases 71 (9), 2428-2446, 2020 | 1286 | 2020 |
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory … H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ... The Lancet Microbe 1 (1), e14-e23, 2020 | 899 | 2020 |
Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset JFW Chan, Y Yao, ML Yeung, W Deng, L Bao, L Jia, F Li, C Xiao, H Gao, ... The Journal of infectious diseases 212 (12), 1904-1913, 2015 | 813 | 2015 |
Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ... Clinical infectious diseases 71 (6), 1400-1409, 2020 | 769 | 2020 |
Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin, X Huang, C Yoon, ... Nature 603 (7902), 693-699, 2022 | 614 | 2022 |
Infection of bat and human intestinal organoids by SARS-CoV-2 J Zhou, C Li, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, A Lee, AJ Zhang, ... Nature medicine 26 (7), 1077-1083, 2020 | 581 | 2020 |
SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists CK Yuen, JY Lam, WM Wong, LF Mak, X Wang, H Chu, JP Cai, DY Jin, ... Emerging microbes & infections 9 (1), 1418-1428, 2020 | 564 | 2020 |
Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways H Chu, J Zhou, BHY Wong, C Li, JFW Chan, ZS Cheng, D Yang, D Wang, ... The Journal of infectious diseases 213 (6), 904-914, 2016 | 512 | 2016 |
Surgical mask partition reduces the risk of noncontact transmission in a golden Syrian hamster model for coronavirus disease 2019 (COVID-19) JFW Chan, S Yuan, AJ Zhang, VKM Poon, CCS Chan, ACY Lee, Z Fan, ... Clinical infectious diseases 71 (16), 2139-2149, 2020 | 299 | 2020 |
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system ML Yeung, JLL Teng, L Jia, C Zhang, C Huang, JP Cai, R Zhou, KH Chan, ... Cell 184 (8), 2212-2228. e12, 2021 | 285 | 2021 |
Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation JFW Chan, KH Chan, GKY Choi, KKW To, H Tse, JP Cai, ML Yeung, ... The Journal of infectious diseases 207 (11), 1743-1752, 2013 | 268 | 2013 |
Rat hepatitis E virus as cause of persistent hepatitis after liver transplant S Sridhar, CCY Yip, S Wu, J Cai, AJX Zhang, KH Leung, TWH Chung, ... Emerging infectious diseases 24 (12), 2241, 2018 | 236 | 2018 |
Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from Norway rats supports the murine origin of Betacoronavirus 1 and has implications for the ancestor of … SKP Lau, PCY Woo, KSM Li, AKL Tsang, RYY Fan, HKH Luk, JP Cai, ... Journal of virology 89 (6), 3076-3092, 2015 | 225 | 2015 |
Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests KH Chan, JFW Chan, H Tse, H Chen, CCY Lau, JP Cai, AKL Tsang, ... Journal of Infection 67 (2), 130-140, 2013 | 212 | 2013 |
Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ... The Journal of infectious diseases 222 (5), 734-745, 2020 | 207 | 2020 |
Severe acute respiratory syndrome (SARS) coronavirus ORF8 protein is acquired from SARS-related coronavirus from greater horseshoe bats through recombination SKP Lau, Y Feng, H Chen, HKH Luk, WH Yang, KSM Li, YZ Zhang, ... Journal of virology 89 (20), 10532-10547, 2015 | 198 | 2015 |
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs JFW Chan, CCY Yip, JOL Tsang, KM Tee, JP Cai, KKH Chik, Z Zhu, ... Emerging microbes & infections 5 (1), 1-12, 2016 | 191 | 2016 |
Transmission of rat hepatitis E virus infection to humans in Hong Kong: a clinical and epidemiological analysis S Sridhar, CCY Yip, S Wu, NFS Chew, KH Leung, JFW Chan, PS Zhao, ... Hepatology 73 (1), 10-22, 2021 | 189 | 2021 |