A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein J Tan, BK Sack, D Oyen, I Zenklusen, L Piccoli, S Barbieri, M Foglierini, ... Nature medicine 24 (4), 401-407, 2018 | 216 | 2018 |
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens J Tan, K Pieper, L Piccoli, A Abdi, M Foglierini, R Geiger, C Maria Tully, ... Nature 529 (7584), 105-109, 2016 | 206 | 2016 |
Broadly neutralizing antibodies target the coronavirus fusion peptide C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan, Y Cong, L Wang, ... Science 377 (6607), 728-735, 2022 | 195 | 2022 |
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities K Pieper, J Tan, L Piccoli, M Foglierini, S Barbieri, Y Chen, ... Nature 548 (7669), 597-601, 2017 | 127 | 2017 |
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern H Cho, KK Gonzales-Wartz, D Huang, M Yuan, M Peterson, J Liang, ... Science Translational Medicine 13 (616), eabj5413, 2021 | 109 | 2021 |
The HIV-1-containing macrophage compartment: a perfect cellular niche? J Tan, QJ Sattentau Trends in microbiology 21 (8), 405-412, 2013 | 109 | 2013 |
Tyrosine sulfation of chemokine receptor CCR2 enhances interactions with both monomeric and dimeric forms of the chemokine monocyte chemoattractant protein-1 (MCP-1) JHY Tan, JP Ludeman, J Wedderburn, M Canals, P Hall, SJ Butler, ... Journal of Biological Chemistry 288 (14), 10024-10034, 2013 | 97 | 2013 |
Design and receptor interactions of obligate dimeric mutant of chemokine monocyte chemoattractant protein-1 (MCP-1) JHY Tan, M Canals, JP Ludeman, J Wedderburn, C Boston, SJ Butler, ... Journal of Biological Chemistry 287 (18), 14692-14702, 2012 | 60 | 2012 |
Plasmodium falciparum–specific IgM B cells dominate in children, expand with malaria, and produce functional IgM CS Hopp, P Sekar, A Diouf, K Miura, K Boswell, J Skinner, CM Tipton, ... Journal of Experimental Medicine 218 (4), e20200901, 2021 | 54 | 2021 |
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses C Dacon, L Peng, TH Lin, C Tucker, CCD Lee, Y Cong, L Wang, L Purser, ... Cell Host & Microbe 31 (1), 97-111. e12, 2023 | 40 | 2023 |
Functional human IgA targets a conserved site on malaria sporozoites J Tan, H Cho, T Pholcharee, LS Pereira, S Doumbo, D Doumtabe, ... Science translational medicine 13 (599), eabg2344, 2021 | 31 | 2021 |
The Antibody Response to Plasmodium falciparum: Cues for Vaccine Design and the Discovery of Receptor-Based Antibodies J Tan, L Piccoli, A Lanzavecchia Annual review of Immunology 37 (1), 225-246, 2019 | 30 | 2019 |
Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein LT Wang, LS Pereira, PK Kiyuka, A Schön, NK Kisalu, R Vistein, M Dillon, ... PLoS Pathogens 17 (12), e1010133, 2021 | 28 | 2021 |
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies Y Chen, K Xu, L Piccoli, M Foglierini, J Tan, W Jin, J Gorman, Y Tsybovsky, ... Nature 592 (7855), 639-643, 2021 | 25 | 2021 |
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium HM Callaway, KM Hastie, SL Schendel, H Li, X Yu, J Shek, T Buck, S Hui, ... Cell Reports 42 (1), 2023 | 23 | 2023 |
Lack of affinity signature for germinal center cells that have initiated plasma cell differentiation HJ Sutton, X Gao, HG Kelly, BJ Parker, M Lofgren, C Dacon, D Chatterjee, ... Immunity 57 (2), 245-255. e5, 2024 | 13 | 2024 |
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype JR Barrett, D Pipini, ND Wright, AJR Cooper, G Gorini, D Quinkert, ... Cell 187 (18), 4964-4980. e21, 2024 | 12 | 2024 |
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5 LT Wang, AJR Cooper, B Farrell, K Miura, A Diouf, N Müller-Sienerth, ... Cell 187 (18), 4981-4995. e14, 2024 | 8 | 2024 |
Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype JR Barrett, D Pipini, ND Wright, AJR Cooper, G Gorini, D Quinkert, ... bioRxiv, 2023.10. 04.560576, 2023 | 7 | 2023 |
Comparative Assessment of the Binding and Neutralisation Activity of Bispecific Antibodies Against SARS-CoV-2 Variants AQ Dean, CB Stauft, JD Twomey, J Tan, L Varani, TT Wang, B Zhang Antibody Therapeutics 6 (1), 49-58, 2023 | 6 | 2023 |