Graeme Grimes

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Soavtorji

W BickmoreMRC Human Genetics Unit, University of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
Pradeepa MadapuraQueen Mary University of LondonPreverjeni e-poštni naslov na qmul.ac.uk
Nick GilbertEdinburgh UniversityPreverjeni e-poštni naslov na ed.ac.uk
Duncan SproulCRUK Career Development Fellow, MRC HGU, MRC IGC, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Pleasantine MillMRC Human Genetics Unit, University of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
Andrew P. JacksonUniversity of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
Rachel RigbyExscientiaPreverjeni e-poštni naslov na exscientia.co.uk
Dr Robert S. IllingworthCentre for Regenerative Mediciene & Simons Initiative for the Developing Brain. EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Martin ReijnsSenior Lecturer, The University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
David R FitzPatrickProfessor & Consultant in Paediatric Genetics, MRC Human Genetics Unit, University of EdinburghPreverjeni e-poštni naslov na nhs.net
Martin S. TaylorInstitute of Genetics and Cancer, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
von KriegsheimUniversity of EdinburghPreverjeni e-poštni naslov na IGMM.ed.ac.uk
Susan M FarringtonUniversity of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Heidi SutherlandQUTPreverjeni e-poštni naslov na qut.edu.au
silvia pelusoUniversity of Edinburgh, Institute of Genetics and Molecular MedicinePreverjeni e-poštni naslov na igmm.ed.ac.uk
Nezha BenabdallahInstitute of Genetics and Cancer, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Colin SempleProfessor/Head of Bioinformatics, MRC Human Genetics Unit, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Javier F. CaceresMRC Human Genetics UnitPreverjeni e-poštni naslov na ed.ac.uk
James PrendergastUniversity of EdinburghPreverjeni e-poštni naslov na roslin.ed.ac.uk

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Graeme Grimes

MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh

Preverjeni e-poštni naslov na ed.ac.uk - Domača stran

Bioinformatics NGS Data visualisation Teaching


Naslov Razvrsti po navedbah Razvrsti po letniku Razvrsti po naslovu	Navedeno Navedeno	Leto
Genetic mechanisms of critical illness in COVID-19 E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ... Nature 591 (7848), 92-98, 2021	1467	2021
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021	853	2021
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination R Eskeland, M Leeb, GR Grimes, C Kress, S Boyle, D Sproul, N Gilbert, ... Molecular cell 38 (3), 452-464, 2010	626	2010
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project CF Taylor, D Field, SA Sansone, J Aerts, R Apweiler, M Ashburner, ... Nature biotechnology 26 (8), 889-896, 2008	625	2008
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ... Cell 149 (5), 1008-1022, 2012	538	2012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing MM Pradeepa, HG Sutherland, J Ule, GR Grimes, WA Bickmore PLoS genetics 8 (5), e1002717, 2012	393	2012
Decreased enhancer-promoter proximity accompanying enhancer activation NS Benabdallah, I Williamson, RS Illingworth, L Kane, S Boyle, ... Molecular cell 76 (3), 473-484. e7, 2019	308	2019
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ... Nature genetics 44 (7), 770-776, 2012	286	2012
Histone H3 globular domain acetylation identifies a new class of enhancers MM Pradeepa, GR Grimes, Y Kumar, G Olley, GCA Taylor, R Schneider, ... Nature genetics 48 (6), 681-686, 2016	262	2016
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ... The EMBO journal 35 (8), 831-844, 2016	253	2016
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly LA Lettice, I Williamson, JH Wiltshire, S Peluso, PS Devenney, AE Hill, ... Developmental cell 22 (2), 459-467, 2012	194	2012
A prenylated dsRNA sensor protects against severe COVID-19 A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ... Science 374 (6567), eabj3624, 2021	192	2021
Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF F Semple, H MacPherson, S Webb, SL Cox, LJ Mallin, C Tyrrell, ... European journal of immunology 41 (11), 3291-3300, 2011	169	2011
BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome G Olley, M Ansari, H Bengani, GR Grimes, J Rhodes, A von Kriegsheim, ... Nature Genetics 50 (3), 329-332, 2018	133	2018
DNA methylation directs polycomb-dependent 3D genome re-organization in naive pluripotency K McLaughlin, IM Flyamer, JP Thomson, HK Mjoseng, R Shukla, ... Cell Reports 29 (7), 1974-1985. e6, 2019	100	2019
DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans D Longman, N Hug, M Keith, C Anastasaki, EE Patton, G Grimes, ... Nucleic acids research 41 (17), 8319-8331, 2013	98	2013
Anterior-posterior differences in HoxD chromatin topology in limb development I Williamson, R Eskeland, LA Lettice, AE Hill, S Boyle, GR Grimes, RE Hill, ... Development 139 (17), 3157-3167, 2012	84	2012
PRC1 and PRC2 are not required for targeting of H2A. Z to developmental genes in embryonic stem cells RS Illingworth, CH Botting, GR Grimes, WA Bickmore, R Eskeland PloS one 7 (4), e34848, 2012	48	2012
Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma A Ewing, A Meynert, M Churchman, GR Grimes, RL Hollis, CS Herrington, ... Clinical Cancer Research 27 (11), 3201-3214, 2021	41	2021
Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins MM Pradeepa, GR Grimes, GCA Taylor, HG Sutherland, WA Bickmore Nucleic acids research 42 (14), 9021-9032, 2014	39	2014

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