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Brooke E Harcourt
Brooke E Harcourt
Preverjeni e-poštni naslov na mcri.edu.au
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Leto
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
MT Coughlan, DR Thorburn, SA Penfold, A Laskowski, BE Harcourt, ...
Journal of the American Society of Nephrology 20 (4), 742-752, 2009
5292009
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
SZ Hasnain, DJ Borg, BE Harcourt, H Tong, YH Sheng, CP Ng, I Das, ...
Nature medicine 20 (12), 1417-1426, 2014
2742014
Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes
MT Coughlan, TV Nguyen, SA Penfold, GC Higgins, V Thallas-Bonke, ...
Clinical science 130 (9), 711-720, 2016
1642016
Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs
C Tikellis, MC Thomas, BE Harcourt, MT Coughlan, J Pete, K Bialkowski, ...
American Journal of Physiology-Endocrinology and Metabolism 295 (2), E323-E330, 2008
1592008
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes
KC Sourris, BE Harcourt, PH Tang, AL Morley, K Huynh, SA Penfold, ...
Free Radical Biology and Medicine 52 (3), 716-723, 2012
1532012
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy
ALY Tan, KC Sourris, BE Harcourt, V Thallas-Bonke, S Penfold, ...
American Journal of Physiology-Renal Physiology 298 (3), F763-F770, 2010
1482010
Targeted reduction of advanced glycation improves renal function in obesity
BE Harcourt, KC Sourris, MT Coughlan, KZ Walker, SL Dougherty, ...
Kidney international 80 (2), 190-198, 2011
1342011
Processed foods drive intestinal barrier permeability and microvascular diseases
M Snelson, SM Tan, RE Clarke, C De Pasquale, V Thallas-Bonke, ...
Science advances 7 (14), eabe4841, 2021
1282021
Coming full circle in diabetes mellitus: from complications to initiation
BE Harcourt, SA Penfold, JM Forbes
Nature Reviews Endocrinology 9 (2), 113-123, 2013
1072013
Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis
MT Coughlan, GC Higgins, TV Nguyen, SA Penfold, V Thallas-Bonke, ...
Diabetes 65 (4), 1085-1098, 2016
732016
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy
K Fukami, S Yamagishi, MT Coughlan, BE Harcourt, P Kantharidis, ...
Diabetology & Metabolic Syndrome 6, 1-9, 2014
502014
A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through disparate therapeutic …
KC Sourris, BE Harcourt, JM Forbes
American Journal of Nephrology 30 (4), 323-335, 2009
462009
Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation
KC Sourris, Y Ding, SS Maxwell, A Al-Sharea, P Kantharidis, M Mohan, ...
Kidney International 105 (1), 132-149, 2024
412024
Targeting the AGE‐RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end‐product content
V Thallas‐Bonke, MT Coughlan, ALY Tan, BE Harcourt, PE Morgan, ...
Nephrology 18 (1), 47-56, 2013
402013
Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes
G Tesch, KC Sourris, SA Summers, D McCarthy, MS Ward, DJ Borg, ...
Diabetologia 57, 1977-1985, 2014
342014
Impairment of liver glycogen storage in the db/db animal model of type 2 diabetes: a potential target for future therapeutics?
M A Sullivan, B E Harcourt, P Xu, J M Forbes, R G Gilbert
Current drug targets 16 (10), 1088-1093, 2015
332015
Modulation of the cellular expression of circulating advanced glycation end‐product receptors in type 2 diabetic nephropathy
KC Sourris, BE Harcourt, SA Penfold, FYT Yap, AL Morley, PE Morgan, ...
Journal of Diabetes Research 2010 (1), 974681, 2010
332010
Evidence for protein leverage in children and adolescents with obesity
C Saner, D Tassoni, BE Harcourt, KT Kao, EJ Alexander, Z McCallum, ...
Obesity 28 (4), 822-829, 2020
302020
A rapid extraction method for glycogen from formalin-fixed liver
MA Sullivan, S Li, STN Aroney, B Deng, C Li, E Roura, BL Schulz, ...
Carbohydrate Polymers 118, 9-15, 2015
302015
Sex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesity
C Saner, BE Harcourt, A Pandey, S Ellul, Z McCallum, KT Kao, ...
Metabolomics 15, 1-11, 2019
282019
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