RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes MT Coughlan, DR Thorburn, SA Penfold, A Laskowski, BE Harcourt, ... Journal of the American Society of Nephrology 20 (4), 742-752, 2009 | 529 | 2009 |
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress SZ Hasnain, DJ Borg, BE Harcourt, H Tong, YH Sheng, CP Ng, I Das, ... Nature medicine 20 (12), 1417-1426, 2014 | 274 | 2014 |
Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes MT Coughlan, TV Nguyen, SA Penfold, GC Higgins, V Thallas-Bonke, ... Clinical science 130 (9), 711-720, 2016 | 164 | 2016 |
Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs C Tikellis, MC Thomas, BE Harcourt, MT Coughlan, J Pete, K Bialkowski, ... American Journal of Physiology-Endocrinology and Metabolism 295 (2), E323-E330, 2008 | 159 | 2008 |
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes KC Sourris, BE Harcourt, PH Tang, AL Morley, K Huynh, SA Penfold, ... Free Radical Biology and Medicine 52 (3), 716-723, 2012 | 153 | 2012 |
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy ALY Tan, KC Sourris, BE Harcourt, V Thallas-Bonke, S Penfold, ... American Journal of Physiology-Renal Physiology 298 (3), F763-F770, 2010 | 148 | 2010 |
Targeted reduction of advanced glycation improves renal function in obesity BE Harcourt, KC Sourris, MT Coughlan, KZ Walker, SL Dougherty, ... Kidney international 80 (2), 190-198, 2011 | 134 | 2011 |
Processed foods drive intestinal barrier permeability and microvascular diseases M Snelson, SM Tan, RE Clarke, C De Pasquale, V Thallas-Bonke, ... Science advances 7 (14), eabe4841, 2021 | 128 | 2021 |
Coming full circle in diabetes mellitus: from complications to initiation BE Harcourt, SA Penfold, JM Forbes Nature Reviews Endocrinology 9 (2), 113-123, 2013 | 107 | 2013 |
Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis MT Coughlan, GC Higgins, TV Nguyen, SA Penfold, V Thallas-Bonke, ... Diabetes 65 (4), 1085-1098, 2016 | 73 | 2016 |
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy K Fukami, S Yamagishi, MT Coughlan, BE Harcourt, P Kantharidis, ... Diabetology & Metabolic Syndrome 6, 1-9, 2014 | 50 | 2014 |
A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through disparate therapeutic … KC Sourris, BE Harcourt, JM Forbes American Journal of Nephrology 30 (4), 323-335, 2009 | 46 | 2009 |
Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation KC Sourris, Y Ding, SS Maxwell, A Al-Sharea, P Kantharidis, M Mohan, ... Kidney International 105 (1), 132-149, 2024 | 41 | 2024 |
Targeting the AGE‐RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end‐product content V Thallas‐Bonke, MT Coughlan, ALY Tan, BE Harcourt, PE Morgan, ... Nephrology 18 (1), 47-56, 2013 | 40 | 2013 |
Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes G Tesch, KC Sourris, SA Summers, D McCarthy, MS Ward, DJ Borg, ... Diabetologia 57, 1977-1985, 2014 | 34 | 2014 |
Impairment of liver glycogen storage in the db/db animal model of type 2 diabetes: a potential target for future therapeutics? M A Sullivan, B E Harcourt, P Xu, J M Forbes, R G Gilbert Current drug targets 16 (10), 1088-1093, 2015 | 33 | 2015 |
Modulation of the cellular expression of circulating advanced glycation end‐product receptors in type 2 diabetic nephropathy KC Sourris, BE Harcourt, SA Penfold, FYT Yap, AL Morley, PE Morgan, ... Journal of Diabetes Research 2010 (1), 974681, 2010 | 33 | 2010 |
Evidence for protein leverage in children and adolescents with obesity C Saner, D Tassoni, BE Harcourt, KT Kao, EJ Alexander, Z McCallum, ... Obesity 28 (4), 822-829, 2020 | 30 | 2020 |
A rapid extraction method for glycogen from formalin-fixed liver MA Sullivan, S Li, STN Aroney, B Deng, C Li, E Roura, BL Schulz, ... Carbohydrate Polymers 118, 9-15, 2015 | 30 | 2015 |
Sex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesity C Saner, BE Harcourt, A Pandey, S Ellul, Z McCallum, KT Kao, ... Metabolomics 15, 1-11, 2019 | 28 | 2019 |