| First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer BJ Solomon, T Mok, DW Kim, YL Wu, K Nakagawa, T Mekhail, E Felip, ... New England Journal of Medicine 371 (23), 2167-2177, 2014 | 3742 | 2014 |
| Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label … TSK Mok, YL Wu, I Kudaba, DM Kowalski, BC Cho, HZ Turna, G Castro, ... The Lancet 393 (10183), 1819-1830, 2019 | 3283 | 2019 |
| A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature medicine 24 (7), 994-1004, 2018 | 1046 | 2018 |
| Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 918 | 2018 |
| RNA-Seq signatures normalized by mRNA abundance allow absolute deconvolution of human immune cell types G Monaco, B Lee, W Xu, S Mustafah, YY Hwang, C Carré, N Burdin, ... Cell reports 26 (6), 1627-1640. e7, 2019 | 795 | 2019 |
| Four functionally distinct populations of human effector-memory CD8+ T lymphocytes P Romero, A Zippelius, I Kurth, MJ Pittet, C Touvrey, EM Iancu, P Corthesy, ... The Journal of Immunology 178 (7), 4112-4119, 2007 | 532 | 2007 |
| CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors H Wang, F Franco, YC Tsui, X Xie, MP Trefny, R Zappasodi, SR Mohmood, ... Nature immunology 21 (3), 298-308, 2020 | 521 | 2020 |
| Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance A Zippelius, P Batard, V Rubio-Godoy, G Bioley, D Liénard, F Lejeune, ... Cancer research 64 (8), 2865-2873, 2004 | 453 | 2004 |
| Selective survival of naturally occurring human CD4+ CD25+ Foxp3+ regulatory T cells cultured with rapamycin L Strauss, TL Whiteside, A Knights, C Bergmann, A Knuth, A Zippelius The Journal of Immunology 178 (1), 320-329, 2007 | 430 | 2007 |
| Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors DS Thommen, J Schreiner, P Müller, P Herzig, A Roller, A Belousov, ... Cancer immunology research 3 (12), 1344-1355, 2015 | 420 | 2015 |
| Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial M Pless, R Stupp, HB Ris, RA Stahel, W Weder, S Thierstein, MA Gerard, ... The Lancet 386 (9998), 1049-1056, 2015 | 414 | 2015 |
| Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion YR Yu, H Imrichova, H Wang, T Chao, Z Xiao, M Gao, M Rincon-Restrepo, ... Nature immunology 21 (12), 1540-1551, 2020 | 401 | 2020 |
| The immune system and cancer evasion strategies: therapeutic concepts S Muenst, H Läubli, SD Soysal, A Zippelius, A Tzankov, S Hoeller Journal of internal medicine 279 (6), 541-562, 2016 | 389 | 2016 |
| Association of checkpoint inhibitor–induced toxic effects with shared cancer and tissue antigens in non–small cell lung cancer F Berner, D Bomze, S Diem, OH Ali, M Fässler, S Ring, R Niederer, ... JAMA oncology 5 (7), 1043-1047, 2019 | 367 | 2019 |
| Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade P Müller, M Kreuzaler, T Khan, DS Thommen, K Martin, K Glatz, S Savic, ... Science translational medicine 7 (315), 315ra188-315ra188, 2015 | 367 | 2015 |
| Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow. A Zippelius, P Kufer, G Honold, MW Köllermann, R Oberneder, ... Journal of Clinical Oncology 15 (7), 2701-2708, 1997 | 356 | 1997 |
| Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma. heinz laeubli, A Zippelius | 349* | |
| Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells MA Stanczak, SS Siddiqui, MP Trefny, DS Thommen, KF Boligan, ... The Journal of clinical investigation 128 (11), 4912-4923, 2018 | 279 | 2018 |
| Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for … E Putz, K Witter, S Offner, P Stosiek, A Zippelius, J Johnson, R Zahn, ... Cancer research 59 (1), 241-248, 1999 | 260 | 1999 |
| An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer P Voabil, M de Bruijn, LM Roelofsen, SH Hendriks, S Brokamp, ... Nature medicine 27 (7), 1250-1261, 2021 | 254 | 2021 |
