Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model H Yu, RD Koilkonda, TH Chou, V Porciatti, SS Ozdemir, V Chiodo, ... Proceedings of the National Academy of Sciences 109 (20), E1238-E1247, 2012 | 194 | 2012 |
Safety and effects of the vector for the Leber hereditary optic neuropathy gene therapy clinical trial RD Koilkonda, H Yu, TH Chou, WJ Feuer, M Ruggeri, V Porciatti, D Tse, ... JAMA ophthalmology 132 (4), 409-420, 2014 | 116 | 2014 |
Efficiency and safety of AAV-mediated gene delivery of the human ND4 complex I subunit in the mouse visual system J Guy, X Qi, RD Koilkonda, T Arguello, TH Chou, M Ruggeri, V Porciatti, ... Investigative ophthalmology & visual science 50 (9), 4205-4214, 2009 | 104 | 2009 |
Robust mouse pattern electroretinograms derived simultaneously from each eye using a common snout electrode TH Chou, J Bohorquez, J Toft-Nielsen, O Ozdamar, V Porciatti Investigative ophthalmology & visual science 55 (4), 2469-2475, 2014 | 77 | 2014 |
A novel mouse model of traumatic optic neuropathy using external ultrasound energy to achieve focal, indirect optic nerve injury W Tao, G Dvoriantchikova, BC Tse, S Pappas, TH Chou, M Tapia, ... Scientific reports 7 (1), 11779, 2017 | 59 | 2017 |
Postnatal elongation of eye size in DBA/2J mice compared with C57BL/6J mice: in vivo analysis with whole-eye OCT TH Chou, OP Kocaoglu, D Borja, M Ruggeri, SR Uhlhorn, F Manns, ... Investigative ophthalmology & visual science 52 (6), 3604-3612, 2011 | 57 | 2011 |
Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus RD Koilkonda, TH Chou, V Porciatti, WW Hauswirth, J Guy Archives of ophthalmology 128 (7), 876-883, 2010 | 54 | 2010 |
Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice H Yu, SS Ozdemir, RD Koilkonda, TH Chou, V Porciatti, V Chiodo, ... Molecular Vision 18, 1668, 2012 | 52 | 2012 |
Nicotinamide-rich diet in DBA/2J mice preserves retinal ganglion cell metabolic function as assessed by PERG adaptation to flicker TH Chou, GL Romano, R Amato, V Porciatti Nutrients 12 (7), 1910, 2020 | 50 | 2020 |
Retrograde signaling in the optic nerve is necessary for electrical responsiveness of retinal ganglion cells TH Chou, KK Park, X Luo, V Porciatti Investigative ophthalmology & visual science 54 (2), 1236-1243, 2013 | 50 | 2013 |
P2X7 receptor antagonism preserves retinal ganglion cells in glaucomatous mice GL Romano, R Amato, F Lazzara, V Porciatti, TH Chou, F Drago, ... Biochemical pharmacology 180, 114199, 2020 | 45 | 2020 |
NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS V Talla, H Yu, TH Chou, V Porciatti, V Chiodo, SL Boye, WW Hauswirth, ... Molecular therapy 21 (10), 1876-1888, 2013 | 39 | 2013 |
C57BL/6J, DBA/2J, and DBA/2J. Gpnmb+ mice have different visual signal processing in the inner retina V Porciatti, TH Chou, WJ Feuer Molecular vision 16, 2939, 2010 | 34 | 2010 |
Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice H Yu, RD Koilkonda, TH Chou, V Porciatti, A Mehta, ID Hentall, ... Proceedings of the National Academy of Sciences 112 (42), E5689-E5698, 2015 | 32 | 2015 |
1α,25-dihydroxyvitamin D3 protects retinal ganglion cells in glaucomatous mice F Lazzara, R Amato, CBM Platania, F Conti, TH Chou, V Porciatti, F Drago, ... Journal of neuroinflammation 18, 1-19, 2021 | 29 | 2021 |
Anesthetic preconditioning as endogenous neuroprotection in glaucoma TH Chou, GR Musada, GL Romano, E Bolton, V Porciatti International journal of molecular sciences 19 (1), 237, 2018 | 27 | 2018 |
Evaluation of a transgenic mouse model of multiple sclerosis with noninvasive methods M Enriquez-Algeciras, D Ding, TH Chou, J Wang, KR Padgett, V Porciatti, ... Investigative ophthalmology & visual science 52 (5), 2405-2411, 2011 | 26 | 2011 |
Protection of pattern electroretinogram and retinal ganglion cells by oncostatin M after optic nerve injury X Xia, R Wen, TH Chou, Y Li, Z Wang, V Porciatti PloS one 9 (9), e108524, 2014 | 24 | 2014 |
Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells G Dvoriantchikova, A Pronin, S Kurtenbach, A Toychiev, TH Chou, ... Scientific reports 8 (1), 5797, 2018 | 22 | 2018 |
Transgenic mice expressing mutated Tyr437His human myocilin develop progressive loss of retinal ganglion cell electrical responsiveness and axonopathy with normal iop TH Chou, S Tomarev, V Porciatti Investigative ophthalmology & visual science 55 (9), 5602-5609, 2014 | 21 | 2014 |