| Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress. SD Yan, X Chen, AM Schmidt, J Brett, G Godman, YS Zou, CW Scott, ... Proceedings of the National Academy of Sciences 91 (16), 7787-7791, 1994 | 803 | 1994 |
| Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration RV Bhat, J Shanley, MP Correll, WE Fieles, RA Keith, CW Scott, CM Lee Proceedings of the National Academy of Sciences 97 (20), 11074-11079, 2000 | 499 | 2000 |
| Phosphorylation of recombinant tau by cAMP-dependent protein kinase. Identification of phosphorylation sites and effect on microtubule assembly. CW Scott, RC Spreen, JL Herman, FP Chow, MD Davison, J Young, ... Journal of Biological Chemistry 268 (2), 1166-1173, 1993 | 260 | 1993 |
| Label-free whole-cell assays: expanding the scope of GPCR screening CW Scott, MF Peters Drug discovery today 15 (17-18), 704-716, 2010 | 198 | 2010 |
| Human induced pluripotent stem cells and their use in drug discovery for toxicity testing CW Scott, MF Peters, YP Dragan Toxicology letters 219 (1), 49-58, 2013 | 194 | 2013 |
| Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase T Asano, SE Pedersen, CW Scott, E Ross Biochemistry 23 (23), 5460-5467, 1984 | 181 | 1984 |
| Proteolysis‐targeting chimeras in drug development: a safety perspective K Moreau, M Coen, AX Zhang, F Pachl, MP Castaldi, G Dahl, H Boyd, ... British journal of pharmacology 177 (8), 1709-1718, 2020 | 175 | 2020 |
| Alcohol oxidase assembles post-translationally into the peroxisome of Candida boidinii. JM Goodman, CW Scott, PN Donahue, JP Atherton Journal of Biological Chemistry 259 (13), 8485-8493, 1984 | 140 | 1984 |
| Evaluating cellular impedance assays for detection of GPCR pleiotropic signaling and functional selectivity MF Peters, CW Scott SLAS Discovery 14 (3), 246-255, 2009 | 138 | 2009 |
| Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert. Identification of threonine 39 as the primary phosphate acceptor. JA Greenwood, CW Scott, RC Spreen, CB Caputo, GV Johnson Journal of Biological Chemistry 269 (6), 4373-4380, 1994 | 128 | 1994 |
| An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility CW Scott, X Zhang, N Abi-Gerges, SD Lamore, YA Abassi, MF Peters Toxicological Sciences 142 (2), 331-338, 2014 | 118 | 2014 |
| Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line MF Peters, SD Lamore, L Guo, CW Scott, KL Kolaja Cardiovascular Toxicology 15, 127-139, 2015 | 105 | 2015 |
| Comparing label-free biosensors for pharmacological screening with cell-based functional assays MF Peters, F Vaillancourt, M Heroux, M Valiquette, CW Scott Assay and drug development technologies 8 (2), 219-227, 2010 | 101 | 2010 |
| Evaluation of cellular dielectric spectroscopy, a whole-cell, label-free technology for drug discovery on Gi-coupled GPCRs MF Peters, KS Knappenberger, D Wilkins, LA Sygowski, LA Lazor, J Liu, ... SLAS Discovery 12 (3), 312-319, 2007 | 95 | 2007 |
| Novel small molecule inhibitors of caspase-3 block cellular and biochemical features of apoptosis CW Scott, C Sobotka-Briner, DE Wilkins, RT Jacobs, JJ Folmer, ... The Journal of pharmacology and experimental therapeutics 304 (1), 433-440, 2003 | 91 | 2003 |
| Tau protein induces bundling of microtubules in vitro: comparison of different tau isoforms and a tau protein fragment CW Scott, AB Klika, MMS Lo, TE Norris, CB Caputo Journal of neuroscience research 33 (1), 19-29, 1992 | 89 | 1992 |
| Aggregation of tau protein by aluminum CW Scott, A Fieles, LA Sygowski, CB Caputo Brain research 628 (1-2), 77-84, 1993 | 80 | 1993 |
| Developing in vitro assays to transform gastrointestinal safety assessment: potential for microphysiological systems MF Peters, AL Choy, C Pin, DJ Leishman, A Moisan, L Ewart, ... Lab on a Chip 20 (7), 1177-1190, 2020 | 73 | 2020 |
| Mechanism of γ-secretase cleavage activation: is γ-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop? KS Knappenberger, G Tian, X Ye, C Sobotka-Briner, SV Ghanekar, ... Biochemistry 43 (20), 6208-6218, 2004 | 72 | 2004 |
| A Homogeneous in Vitro Functional Assay for Estrogen Receptors: Coactivator Recruitment J Liu, KS Knappenberger, H Käck, G Andersson, E Nilsson, C Dartsch, ... Molecular endocrinology 17 (3), 346-355, 2003 | 71 | 2003 |
