Stefan Knapp

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Soavtorji

Panagis FilippakopoulosAssociate Professor, Oxford UniversityPreverjeni e-poštni naslov na sgc.ox.ac.uk
Oleg FedorovUniversity of OxfordPreverjeni e-poštni naslov na cmd.ox.ac.uk
Apirat ChaikuadPreverjeni e-poštni naslov na pharmchem.uni-frankfurt.de
Paul E BrennanUniversity of OxfordPreverjeni e-poštni naslov na cmd.ox.ac.uk
Frank von DelftPrincipal Investigator: Protein Crystallography, SGC, Oxford UniversityPreverjeni e-poštni naslov na sgc.ox.ac.uk
Brian MarsdenCentre for Medicines Discovery & Centre for Human Genetics, NDM, University of OxfordPreverjeni e-poštni naslov na cmd.ox.ac.uk
Cheryl ArrowsmithSenior Scientist, Princess Margaret Cancer Centre & Professor of Medical Biophysics, University of TorontoPreverjeni e-poštni naslov na uhnres.utoronto.ca
Sebastian MatheaPreverjeni e-poštni naslov na pharmchem.uni-frankfurt.de
Wen Hwa LeeAction Against AMD, SGC and University of OxfordPreverjeni e-poštni naslov na actionagainstamd.org
Benjamin E. TurkYale UniversityPreverjeni e-poštni naslov na yale.edu
Jeyanthy EswaranSaint Jude's Children's Research HospitalPreverjeni e-poštni naslov na stjude.org
Chas BountraProfessor of Translational MedicinePreverjeni e-poštni naslov na cmd.ox.ac.uk
Martin SchröderNovartis Institute for Biomedical ResearchPreverjeni e-poštni naslov na novartis.com
Opher GileadiSGC, Karolinska InstitutePreverjeni e-poštni naslov na ki.se
Ashley PikeCentre for Medicines Discovery - University of OxfordPreverjeni e-poštni naslov na cmd.ox.ac.uk
Juerg SchwallerProfessor Universität BaselPreverjeni e-poštni naslov na unibas.ch
Kilian V. M. HuberPrincipal Investigator, University of OxfordPreverjeni e-poštni naslov na cmd.ox.ac.uk
Stuart J ConwayJung Chair in Medicinal Chemistry, University of California, Los AngelesPreverjeni e-poštni naslov na chem.ucla.edu
Daniel MerkETH Zurich, Switzerland; Goethe University Frankfurt, GermanyPreverjeni e-poštni naslov na pharmchem.uni-frankfurt.de
Laurent MeijerPreverjeni e-poštni naslov na manros-therapeutics.com

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Stefan Knapp

University of Frankfurt

Preverjeni e-poštni naslov na pharmchem.uni-frankfurt.de

bromodomains kinases structural biology drug design


Naslov Razvrsti po navedbah Razvrsti po letniku Razvrsti po naslovu	Navedeno Navedeno	Leto
Selective inhibition of BET bromodomains P Filippakopoulos, J Qi, S Picaud, Y Shen, WB Smith, O Fedorov, ... Nature 468 (7327), 1067-1073, 2010	4529	2010
Histone recognition and large-scale structural analysis of the human bromodomain family P Filippakopoulos, S Picaud, M Mangos, T Keates, JP Lambert, ... Cell 149 (1), 214-231, 2012	1840	2012
Targeting bromodomains: epigenetic readers of lysine acetylation P Filippakopoulos, S Knapp Nature reviews Drug discovery 13 (5), 337-356, 2014	1379	2014
Protein production and purification Architecture et Fonction des Macromolécules Biologiques Vincentelli Renaud 4 ... Nature methods 5 (2), 135-146, 2008	1035	2008
The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015	894	2015
Critical residues for structure and catalysis in short-chain dehydrogenases/reductases C Filling, KD Berndt, J Benach, S Knapp, T Prozorovski, E Nordling, ... Journal of Biological Chemistry 277 (28), 25677-25684, 2002	705	2002
The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs KL Kavanagh, K Guo, JE Dunford, X Wu, S Knapp, FH Ebetino, ... Proceedings of the National Academy of Sciences 103 (20), 7829-7834, 2006	678	2006
Trends in kinase drug discovery: targets, indications and inhibitor design MM Attwood, D Fabbro, AV Sokolov, S Knapp, HB Schiöth Nature Reviews Drug Discovery 20 (11), 839-861, 2021	609	2021
Copper is required for oncogenic BRAF signalling and tumorigenesis DC Brady, MS Crowe, ML Turski, GA Hobbs, X Yao, A Chaikuad, S Knapp, ... Nature 509 (7501), 492-496, 2014	583	2014
Bromodomains as therapeutic targets S Muller, P Filippakopoulos, S Knapp Expert reviews in molecular medicine 13, e29, 2011	567	2011
Large-scale structural analysis of the classical human protein tyrosine phosphatome AJ Barr, E Ugochukwu, WH Lee, ONF King, P Filippakopoulos, I Alfano, ... Cell 136 (2), 352-363, 2009	562	2009
Linear motif atlas for phosphorylation-dependent signaling ML Miller, LJ Jensen, F Diella, C Jørgensen, M Tinti, L Li, M Hsiung, ... Science signaling 1 (35), ra2-ra2, 2008	532	2008
Small-molecule inhibition of BRDT for male contraception MM Matzuk, MR McKeown, P Filippakopoulos, Q Li, L Ma, JE Agno, ... Cell 150 (4), 673-684, 2012	528	2012
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain S Picaud, C Wells, I Felletar, D Brotherton, S Martin, P Savitsky, ... Proceedings of the National Academy of Sciences 110 (49), 19754-19759, 2013	512	2013
The bromodomain interaction module P Filippakopoulos, S Knapp FEBS letters 586 (17), 2692-2704, 2012	470	2012
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ... Nature 508 (7495), 222-227, 2014	455	2014
Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery? Z Zhao, H Wu, L Wang, Y Liu, S Knapp, Q Liu, NS Gray ACS chemical biology 9 (6), 1230-1241, 2014	443	2014
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers L Brault, C Gasser, F Bracher, K Huber, S Knapp, J Schwaller haematologica 95 (6), 1004, 2010	439	2010
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases O Fedorov, B Marsden, V Pogacic, P Rellos, S Müller, AN Bullock, ... Proceedings of the National Academy of Sciences 104 (51), 20523-20528, 2007	424	2007
Crystal structure of the tetrameric Mad1–Mad2 core complex: implications of a ‘safety belt’binding mechanism for the spindle checkpoint L Sironi, M Mapelli, S Knapp, A De Antoni, KT Jeang, A Musacchio The EMBO journal, 2002	394	2002

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