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Jeff MacKeigan
Jeff MacKeigan
Senior Advisor, Office of Research & Innovation; Professor, Pediatrics and Human Development; MSU
Preverjeni e-poštni naslov na msu.edu - Domača stran
Naslov
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Navedeno
Leto
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13540*2021
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
K Düvel, JL Yecies, S Menon, P Raman, AI Lipovsky, AL Souza, ...
Molecular cell 39 (2), 171-183, 2010
23642010
Bidirectional transport of amino acids regulates mTOR and autophagy
P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ...
Cell 136 (3), 521-534, 2009
20502009
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
JP MacKeigan, LO Murphy, J Blenis
Nature cell biology 7 (6), 591-600, 2005
7362005
A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration
LO Murphy, JP MacKeigan, J Blenis
Molecular and cellular biology 24 (1), 144-153, 2004
4442004
Guidelines for the use and interpretation of assays for monitoring autophagy
A Diwan, S Hwang, I Mysorekar, WA Weiss
315*2012
MEK inhibition enhances paclitaxel-induced tumor apoptosis
JP MacKeigan, TS Collins, JPY Ting
Journal of Biological Chemistry 275 (50), 38953-38956, 2000
2852000
Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
BA Ballif, PP Roux, SA Gerber, JP MacKeigan, J Blenis, SP Gygi
Proceedings of the National Academy of Sciences 102 (3), 667-672, 2005
2732005
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIα
JP MacKeigan, CM Clements, JD Lich, RM Pope, Y Hod, JPY Ting
Cancer research 63 (20), 6928-6934, 2003
2292003
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
MS Stark, SL Woods, MG Gartside, VF Bonazzi, K Dutton-Regester, ...
Nature genetics 44 (2), 165-169, 2012
2262012
The genomic landscape of tuberous sclerosis complex
KR Martin, W Zhou, MJ Bowman, J Shih, KS Au, KE Dittenhafer-Reed, ...
Nature communications 8 (1), 15816, 2017
2192017
Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex
JP MacKeigan, DA Krueger
Neuro-oncology 17 (12), 1550-1559, 2015
1992015
Mitochondria in cancer: at the crossroads of life and death
VC Fogg, NJ Lanning, JP MacKeigan
Chinese journal of cancer 30 (8), 526, 2011
1932011
Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
NJ Lanning, JP Castle, SJ Singh, AN Leon, EA Tovar, A Sanghera, ...
Cancer & metabolism 5, 1-14, 2017
1802017
Biodistribution of radiolabeled lipid–DNA complexes and DNA in mice
R Niven, R Pearlman, T Wedeking, J Mackeigan, P Noker, ...
Journal of pharmaceutical sciences 87 (11), 1292-1299, 1998
1601998
A potent and selective ULK1 inhibitor suppresses autophagy and sensitizes cancer cells to nutrient stress
KR Martin, SL Celano, AR Solitro, H Gunaydin, M Scott, RC O'Hagan, ...
Iscience 8, 74-84, 2018
1412018
STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma
BD Looyenga, D Hutchings, I Cherni, C Kingsley, GJ Weiss, ...
PloS one 7 (2), e30820, 2012
1382012
Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo
CA Dimitri, W Dowdle, JP MacKeigan, J Blenis, LO Murphy
Current Biology 15 (14), 1319-1324, 2005
1352005
Mitochondrial morphological features are associated with fission and fusion events
LM Westrate, JA Drocco, KR Martin, WS Hlavacek, JP MacKeigan
PloS one 9 (4), e95265, 2014
1322014
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
ML Goodall, T Wang, KR Martin, MG Kortus, AL Kauffman, JM Trent, ...
Autophagy 10 (6), 1120-1136, 2014
1272014
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