Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature GI Rice, PR Kasher, GMA Forte, NM Mannion, SM Greenwood, ... Nature genetics 44 (11), 1243-1248, 2012 | 936 | 2012 |
The RNA-editing enzyme ADAR1 controls innate immune responses to RNA NM Mannion, SM Greenwood, R Young, S Cox, J Brindle, D Read, ... Cell reports 9 (4), 1482-1494, 2014 | 626 | 2014 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 615 | 2017 |
A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity MJ Palladino, LP Keegan, MA O'Connell, RA Reenan Cell 102 (4), 437-449, 2000 | 457 | 2000 |
Identifying RNA editing sites using RNA sequencing data alone G Ramaswami, R Zhang, R Piskol, LP Keegan, P Deng, MA O'connell, ... Nature methods 10 (2), 128-132, 2013 | 407 | 2013 |
The many roles of an RNA editor LP Keegan, A Gallo, MA O'Connell Nature Reviews Genetics 2 (11), 869-878, 2001 | 372 | 2001 |
Dynamic association of RNA-editing enzymes with the nucleolus JMP Desterro, LP Keegan, M Lafarga, MT Berciano, M O'Connell, ... Journal of cell science 116 (9), 1805-1818, 2003 | 335 | 2003 |
Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase MA O'Connell, S Krause, M Higuchi, JJ Hsuan, NF Totty, A Jenny, ... Molecular and cellular biology 15 (3), 1389-1397, 1995 | 324 | 1995 |
A standardized nomenclature for adenosine deaminases that act on RNA BL Bass, K Nishikura, W Keller, PH Seeburg, RB Emeson, MA O'connell, ... Rna 3 (9), 947, 1997 | 289 | 1997 |
Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette A Gerber, MA O'Connell, W Keller Rna 3 (5), 453, 1997 | 244 | 1997 |
Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation C Cenci, R Barzotti, F Galeano, S Corbelli, R Rota, L Massimi, C Di Rocco, ... Journal of Biological Chemistry 283 (11), 7251-7260, 2008 | 232 | 2008 |
dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing MJ Palladino, LP Keegan, MA O'CONNELL, RA Reenan Rna 6 (7), 1004-1018, 2000 | 230 | 2000 |
Editing independent effects of ADARs on the miRNA/siRNA pathways BSE Heale, LP Keegan, L McGurk, G Michlewski, J Brindle, CM Stanton, ... The EMBO journal 28 (20), 3145-3156, 2009 | 218 | 2009 |
Microsatellite DNA analysis of population structure in Atlantic herring (Clupea harengus), with direct comparison to allozyme and mtDNA RFLP analyses PW Shaw, C Turan, JM Wright, M O’connell, GR Carvalho Heredity 83 (4), 490-499, 1999 | 215 | 1999 |
Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes LP Keegan, A Leroy, D Sproul, MA O'Connell Genome biology 5, 1-10, 2004 | 189 | 2004 |
Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase S Maas, T Melcher, A Herb, PH Seeburg, W Keller, S Krause, M Higuchi, ... Journal of Biological Chemistry 271 (21), 12221-12226, 1996 | 170 | 1996 |
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects R Marcucci, J Brindle, S Paro, A Casadio, S Hempel, N Morrice, A Bisso, ... The EMBO journal 30 (20), 4211-4222, 2011 | 153 | 2011 |
An ADAR that edits transcripts encoding ion channel subunits functions as a dimer A Gallo, LP Keegan, GM Ring, MA O'Connell The EMBO journal, 2003 | 150 | 2003 |
ADAR RNA editing in human disease; more to it than meets the I A Gallo, D Vukic, D Michalík, MA O’connell, LP Keegan Human genetics 136, 1265-1278, 2017 | 142 | 2017 |
SUMO-1 modification alters ADAR1 editing activity JMP Desterro, LP Keegan, E Jaffray, RT Hay, MA O'Connell, ... Molecular biology of the cell 16 (11), 5115-5126, 2005 | 140 | 2005 |