| Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex MMU Ali, SM Roe, CK Vaughan, P Meyer, B Panaretou, PW Piper, ... Nature 440 (7087), 1013-1017, 2006 | 1176 | 2006 |
| Structure and molecular mechanism of ER stress signaling by the unfolded protein response signal activator IRE1 CJ Adams, MC Kopp, N Larburu, PR Nowak, MMU Ali Frontiers in molecular biosciences 6, 11, 2019 | 576 | 2019 |
| The mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50cdc37 SM Roe, MMU Ali, P Meyer, CK Vaughan, B Panaretou, PW Piper, ... Cell 116 (1), 87-98, 2004 | 428 | 2004 |
| Structure of an hsp90-cdc37-cdk4 complex CK Vaughan, U Gohlke, F Sobott, VM Good, MMU Ali, C Prodromou, ... Molecular cell 23 (5), 697-707, 2006 | 363 | 2006 |
| UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor MC Kopp, N Larburu, V Durairaj, CJ Adams, MMU Ali Nature structural & molecular biology 26 (11), 1053-1062, 2019 | 338 | 2019 |
| Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response MMU Ali, T Bagratuni, EL Davenport, PR Nowak, MC Silva‐Santisteban, ... The EMBO journal 30 (5), 894-905, 2011 | 310 | 2011 |
| Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistance M Cerezo, A Lehraiki, A Millet, F Rouaud, M Plaisant, E Jaune, T Botton, ... Cancer cell 29 (6), 805-819, 2016 | 260 | 2016 |
| Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling M Carrara, F Prischi, PR Nowak, MC Kopp, MMU Ali Elife 4, e03522, 2015 | 240 | 2015 |
| Interactome screening identifies the ER luminal chaperone Hsp47 as a regulator of the unfolded protein response transducer IRE1α D Sepulveda, D Rojas-Rivera, DA Rodríguez, J Groenendyk, A Köhler, ... Molecular cell 69 (2), 238-252. e7, 2018 | 175 | 2018 |
| Phosphoregulation of Ire1 RNase splicing activity F Prischi, PR Nowak, M Carrara, MMU Ali Nature communications 5 (1), 3554, 2014 | 164 | 2014 |
| Structure of colicin I receptor bound to the R‐domain of colicin Ia: implications for protein import SK Buchanan, P Lukacik, S Grizot, R Ghirlando, MMU Ali, TJ Barnard, ... The EMBO journal 26 (10), 2594-2604, 2007 | 131 | 2007 |
| Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling M Carrara, F Prischi, PR Nowak, MMU Ali The EMBO journal 34 (11), 1589-1600, 2015 | 115 | 2015 |
| In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress MC Kopp, PR Nowak, N Larburu, CJ Adams, MMU Ali Elife 7, e30257, 2018 | 75 | 2018 |
| UPR signal activation by luminal sensor domains M Carrara, F Prischi, MMU Ali International journal of molecular sciences 14 (3), 6454-6466, 2013 | 75 | 2013 |
| Chaperone ligand-discrimination by the TPR-domain protein Tah1 SH Millson, CK Vaughan, C Zhai, MMU Ali, B Panaretou, PW Piper, ... Biochemical Journal 413 (2), 261-268, 2008 | 60 | 2008 |
| Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer S Chrysostomou, R Roy, F Prischi, L Thamlikitkul, KL Chapman, U Mufti, ... Science translational medicine 13 (602), eaba4627, 2021 | 26 | 2021 |
| Mechanism of Hsp70 specialized interactions in protein translocation and the unfolded protein response N Larburu, CJ Adams, CS Chen, PR Nowak, MMU Ali Open Biology 10 (8), 200089, 2020 | 25 | 2020 |
| Targeting RSK4 prevents both chemoresistance and metastasis in lung cancer S Chrysostomou, R Roy, F Prischi, K Chapman, U Mufti, F Mauri, ... Cancer Research 79 (13_Supplement), 1775-1775, 2019 | 3 | 2019 |
| Alternative ATPase domain interactions in eukaryotic Hsp70 chaperones Y Ben-Khoud, CS Chen, MMU Ali Frontiers in Molecular Biosciences 10, 1155784, 2023 | 2 | 2023 |
| OST component RPN1 is a novel regulator of IRE1 RNase activity that interacts with multiple distinct IRE1 and PERK complexes N Larburu, F Storer, Y Ben-Khoud, C Chen, CJ Adams, TD Southall, ... bioRxiv, 2024.12. 17.628858, 2024 | | 2024 |
