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Christopher D McFarland
Christopher D McFarland
Assistant Professor in Genetics & Genome Sciences at Case Western University
Preverjeni e-poštni naslov na case.edu - Domača stran
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Navedeno
Leto
Impact of deleterious passenger mutations on cancer progression
CD McFarland, KS Korolev, GV Kryukov, SR Sunyaev, LA Mirny
Proceedings of the National Academy of Sciences 110 (8), 2910-2915, 2013
3512013
Massively parallel digital transcriptional profiling of single cells. Nat. Commun. 8, 14049
GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
2942017
Tug-of-war between driver and passenger mutations in cancer and other adaptive processes
CD McFarland, LA Mirny, KS Korolev
Proceedings of the National Academy of Sciences 111 (42), 15138-15143, 2014
1752014
A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo
ZN Rogers, CD McFarland, IP Winters, S Naranjo, CH Chuang, D Petrov, ...
Nature methods 14 (7), 737-742, 2017
1412017
The damaging effect of passenger mutations on cancer progression
CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ...
Cancer research 77 (18), 4763-4772, 2017
1372017
Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
ZN Rogers, CD McFarland, IP Winters, JA Seoane, JJ Brady, S Yoon, ...
Nature genetics 50 (4), 483-486, 2018
1272018
Massively parallel digital transcriptional profiling of single cells. Nat Commun. 2017; 8: 14049
GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
1162019
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ...
Nature communications 8 (1), 2053, 2017
1082017
An in vivo multiplexed small-molecule screening platform
BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ...
Nature methods 13 (10), 883-889, 2016
692016
A functional taxonomy of tumor suppression in oncogenic KRAS–driven lung cancer
H Cai, SK Chew, C Li, MK Tsai, L Andrejka, CW Murray, NW Hughes, ...
Cancer discovery 11 (7), 1754-1773, 2021
482021
Most cancers carry a substantial deleterious load due to Hill-Robertson interference
S Tilk, S Tkachenko, C Curtis, DA Petrov, CD McFarland
Elife 11, e67790, 2022
272022
Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma
C Li, WY Lin, H Rizvi, H Cai, CD McFarland, ZN Rogers, M Yousefi, ...
Cancer research 81 (17), 4570-4580, 2021
242021
Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer
JA Yaglom, C McFarland, L Mirny, MY Sherman
Oncotarget 5 (18), 8367, 2014
242014
Seasonal epidemiology of gastrointestinal nematodes of cattle in the northern continental climate zone of western Canada as revealed by internal transcribed spacer-2 ribosomal …
T Wang, EM Redman, A Morosetti, R Chen, S Kulle, N Morden, ...
Parasites & Vectors 14, 1-13, 2021
192021
Tracking gastrointestinal nematode risk on cattle farms through pasture contamination mapping
C McFarland, HR Vineer, L Chesney, N Henry, C Brown, P Airs, ...
International Journal for Parasitology 52 (10), 691-703, 2022
172022
Frequency-dependent ecological interactions increase the prevalence, and shape the distribution, of preexisting drug resistance
J Maltas, DS Tadele, A Durmaz, CD McFarland, M Hinczewski, JG Scott
PRX Life 2 (2), 023010, 2024
132024
Novel epidemiological model of gastrointestinal nematode infection to assess grazing cattle resilience by integrating host growth, parasite, grass and environmental dynamics
JAN Filipe, I Kyriazakis, C McFarland, ER Morgan
International Journal for Parasitology 53 (3), 133-155, 2023
122023
An improved model for the population dynamics of cattle gastrointestinal nematodes on pasture: parameterisation and field validation for Ostertagia ostertagi and Cooperia …
T Wang, HR Vineer, E Redman, A Morosetti, R Chen, C McFarland, ...
Veterinary parasitology 310, 109777, 2022
122022
A modified ziggurat algorithm for generating exponentially and normally distributed pseudorandom numbers
CD McFarland
Journal of Statistical Computation and Simulation, 1-14, 2015
112015
Assessing the microbiota of the snail intermediate host of trematodes, Galba truncatula
P McCann, C McFarland, J Megaw, K Siu-Ting, C Cantacessi, G Rinaldi, ...
Parasites & vectors 17 (1), 31, 2024
82024
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