Sudarshan Rajagopal

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Robert J. LefkowitzJames B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke UniversityPreverjeni e-poštni naslov na receptor-biol.duke.edu
Bastiaan DriehuysDuke UniversityPreverjeni e-poštni naslov na duke.edu
Jeffrey S. SmithHarvard Medical SchoolPreverjeni e-poštni naslov na bwh.harvard.edu
Ziyi WangDuke UniversityPreverjeni e-poštni naslov na duke.edu
Eric J. VelazquezProfessor of Medicine, Yale UniversityPreverjeni e-poštni naslov na yale.edu
Chris LamPreverjeni e-poštni naslov na geisinger.edu
Arun K. ShuklaProfessor and Sonu Agrawal Memorial ChairPreverjeni e-poštni naslov na iitk.ac.in
Fawaz Alenezi, MD, MScDuke University Medical Center, CardiologyPreverjeni e-poštni naslov na dm.duke.edu
Spencer AndersonNorthwestern UniversityPreverjeni e-poštni naslov na ls-cat.org
Makoto R. HaraNovartisPreverjeni e-poštni naslov na novartis.com
Vukica SrajerResearch Professor, Center for Advanced Radiation Sources, The University of ChicagoPreverjeni e-poštni naslov na uchicago.edu
Mu HeUniversity of VirginiaPreverjeni e-poštni naslov na virginia.edu
Keshava RajagopalSidney Kimmel Medical College/Thomas Jefferson UniversityPreverjeni e-poštni naslov na jefferson.edu
Howard RockmanDuke UniversityPreverjeni e-poštni naslov na duke.edu
Zhiyuan MaSt Luke's University Health NetworkPreverjeni e-poštni naslov na sluhn.org
Friedrich SchotteStaff Scientist, National Institutes of HealthPreverjeni e-poštni naslov na nih.gov
Michael WulffESRF, The European SynchrotronPreverjeni e-poštni naslov na esrf.fr
Kelly NoblesUS NavyPreverjeni e-poštni naslov na mail.mil
Terrence OasDuke UniversityPreverjeni e-poštni naslov na duke.edu
Jason KeyHarvard Medical SchoolPreverjeni e-poštni naslov na crystal.harvard.edu

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Sudarshan Rajagopal

Division of Cardiology, Duke University Medical Center

Preverjeni e-poštni naslov na duke.edu - Domača stran

GPCRs Arrestin Signaling Biased Agonism


Naslov Razvrsti po navedbah Razvrsti po letniku Razvrsti po naslovu	Navedeno Navedeno	Leto
Teaching old receptors new tricks: biasing seven-transmembrane receptors S Rajagopal, K Rajagopal, RJ Lefkowitz Nature reviews Drug discovery 9 (5), 373-386, 2010	1036	2010
Biased signalling: from simple switches to allosteric microprocessors JS Smith, RJ Lefkowitz, S Rajagopal Nature reviews Drug discovery 17 (4), 243-260, 2018	752	2018
Distinct phosphorylation sites on the β2-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin KN Nobles, K Xiao, S Ahn, AK Shukla, CM Lam, S Rajagopal, ... Science signaling 4 (185), ra51-ra51, 2011	733	2011
β-arrestin-but not G protein-mediated signaling by the “decoy” receptor CXCR7 S Rajagopal, J Kim, S Ahn, S Craig, CM Lam, NP Gerard, C Gerard, ... Proceedings of the National Academy of Sciences 107 (2), 628-632, 2010	710	2010
Therapeutic potential of β-arrestin-and G protein-biased agonists EJ Whalen, S Rajagopal, RJ Lefkowitz Trends in molecular medicine 17 (3), 126-139, 2011	636	2011
The LOV domain family: photoresponsive signaling modules coupled to diverse output domains S Crosson, S Rajagopal, K Moffat Biochemistry 42 (1), 2-10, 2003	568	2003
A stress response pathway regulates DNA damage through β₂-adrenoreceptors and β-arrestin-1 MR Hara, JJ Kovacs, EJ Whalen, S Rajagopal, RT Strachan, W Grant, ... Nature 477 (7364), 349-353, 2011	515	2011
Quantifying ligand bias at seven-transmembrane receptors S Rajagopal, S Ahn, DH Rominger, W Gowen-MacDonald, CM Lam, ... Molecular pharmacology 80 (3), 367-377, 2011	429	2011
GPCR desensitization: Acute and prolonged phases S Rajagopal, SK Shenoy Cellular signalling 41, 9-16, 2018	388	2018
The β-arrestins: multifunctional regulators of G protein-coupled receptors JS Smith, S Rajagopal Journal of Biological Chemistry 291 (17), 8969-8977, 2016	368	2016
Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds H Ihee, S Rajagopal, V Šrajer, R Pahl, S Anderson, M Schmidt, F Schotte, ... Proceedings of the National Academy of Sciences 102 (20), 7145-7150, 2005	321	2005
Multiple ligand-specific conformations of the β₂-adrenergic receptor AW Kahsai, K Xiao, S Rajagopal, S Ahn, AK Shukla, J Sun, TG Oas, ... Nature chemical biology 7 (10), 692-700, 2011	303	2011
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ... Proceedings of the National Academy of Sciences 107 (34), 15299-15304, 2010	235	2010
How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways K Rajarathnam, M Schnoor, RM Richardson, S Rajagopal Cellular signalling 54, 69-80, 2019	223	2019
Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 LM Luttrell, J Wang, B Plouffe, JS Smith, L Yamani, S Kaur, ... Science signaling 11 (549), eaat7650, 2018	215	2018
Application of singular value decomposition to the analysis of time-resolved macromolecular X-ray data M Schmidt, S Rajagopal, Z Ren, K Moffat Biophysical journal 84 (3), 2112-2129, 2003	193	2003
Community guidelines for GPCR ligand bias: IUPHAR review 32 P Kolb, T Kenakin, SPH Alexander, M Bermudez, LM Bohn, CS Breinholt, ... British journal of pharmacology 179 (14), 3651-3674, 2022	172	2022
Biased agonism as a mechanism for differential signaling by chemokine receptors S Rajagopal, DL Bassoni, JJ Campbell, NP Gerard, C Gerard, ... Journal of Biological Chemistry 288 (49), 35039-35048, 2013	163	2013
Purification and Initial Characterization of a Putative Blue Light‐regulated Phosphodiesterase from Escherichia coli^¶ S Rajagopal, JM Key, EB Purcell, DJ Boerema, K Moffat Photochemistry and photobiology 80 (3), 542-547, 2004	134	2004
Quantitative analysis of hyperpolarized ¹²⁹Xe gas transfer MRI Z Wang, SH Robertson, J Wang, M He, RS Virgincar, GM Schrank, ... Medical physics 44 (6), 2415-2428, 2017	123	2017

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