Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels M Kato, TW Han, S Xie, K Shi, X Du, LC Wu, H Mirzaei, EJ Goldsmith, ... Cell 149 (4), 753-767, 2012 | 2159 | 2012 |
Facile enantioselective synthesis of propargylic alcohols by direct addition of terminal alkynes to aldehydes DE Frantz, R Fässler, EM Carreira Journal of the American Chemical Society 122 (8), 1806-1807, 2000 | 799 | 2000 |
The Discovery of Novel Reactivity in the Development of C−C Bond-Forming Reactions: In Situ Generation of Zinc Acetylides with ZnII/R3N DE Frantz, R Fässler, CS Tomooka, EM Carreira Accounts of chemical research 33 (6), 373-381, 2000 | 523 | 2000 |
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... Nature communications 4 (1), 2035, 2013 | 346 | 2013 |
Efficient enantioselective additions of terminal alkynes and aldehydes under operationally convenient conditions D Boyall, DE Frantz, EM Carreira Organic letters 4 (15), 2605-2606, 2002 | 329 | 2002 |
Allosteric inhibition of hypoxia inducible factor-2 with small molecules TH Scheuermann, Q Li, HW Ma, J Key, L Zhang, R Chen, JA Garcia, ... Nature chemical biology 9 (4), 271-276, 2013 | 326 | 2013 |
Recent advances in the catalytic syntheses of allenes: a critical assessment RK Neff, DE Frantz ACS Catalysis 4 (2), 519-528, 2014 | 284 | 2014 |
Catalytic in situ generation of Zn (II)-alkynilides under mild conditions: a novel CN addition process utilizing terminal acetylenes DE Frantz, R Fässler, EM Carreira Journal of the American Chemical Society 121 (48), 11245-11246, 1999 | 275 | 1999 |
Synthesis of α-amido ketones via organic catalysis: Thiazolium-catalyzed cross-coupling of aldehydes with acylimines JA Murry, DE Frantz, A Soheili, R Tillyer, EJJ Grabowski, PJ Reider Journal of the American Chemical Society 123 (39), 9696-9697, 2001 | 265 | 2001 |
Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species Y Wang, QS Zang, Z Liu, Q Wu, D Maass, G Dulan, PW Shaul, L Melito, ... American Journal of Physiology-Cell Physiology 301 (3), C695-C704, 2011 | 235 | 2011 |
Enantioselective Addition of 2-Methyl-3-butyn-2-ol to Aldehydes: Preparation of 3-Hydroxy-1-butynes D Boyall, F López, H Sasaki, D Frantz, EM Carreira Organic letters 2 (26), 4233-4236, 2000 | 231 | 2000 |
Synthesis of substituted imidazoles via organocatalysis DE Frantz, L Morency, A Soheili, JA Murry, EJJ Grabowski, RD Tillyer Organic Letters 6 (5), 843-846, 2004 | 223 | 2004 |
An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae J Lee, V Sperandio, DE Frantz, J Longgood, A Camilli, MA Phillips, ... Journal of Biological Chemistry 284 (15), 9899-9907, 2009 | 203 | 2009 |
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites CLL Valentim, D Cioli, FD Chevalier, X Cao, AB Taylor, SP Holloway, ... Science 342 (6164), 1385-1389, 2013 | 185 | 2013 |
Cardiogenic small molecules that enhance myocardial repair by stem cells H Sadek, B Hannack, E Choe, J Wang, S Latif, MG Garry, DJ Garry, ... Proceedings of the National Academy of Sciences 105 (16), 6063-6068, 2008 | 174 | 2008 |
Small-molecule activation of neuronal cell fate JW Schneider, Z Gao, S Li, M Farooqi, TS Tang, I Bezprozvanny, ... Nature chemical biology 4 (7), 408-410, 2008 | 171 | 2008 |
13C Kinetic Isotope Effects for the Addition of Lithium Dibutylcuprate to Cyclohexenone. Reductive Elimination Is Rate-Determining DE Frantz, DA Singleton, JP Snyder Journal of the American Chemical Society 119 (14), 3383-3384, 1997 | 149 | 1997 |
Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor JL Rogers, L Bayeh, TH Scheuermann, J Longgood, J Key, J Naidoo, ... Journal of medicinal chemistry 56 (4), 1739-1747, 2013 | 147 | 2013 |
First Synthesis of Optically Pure Propargylic N‐Hydroxylamines by Direct, Highly Diastereoselective Addition of Terminal Alkynes to Nitrones R Fässler, DE Frantz, J Oetiker, EM Carreira Angewandte Chemie International Edition 41 (16), 3054-3056, 2002 | 142 | 2002 |
Pd-catalyzed asymmetric β-hydride elimination en route to chiral allenes IT Crouch, RK Neff, DE Frantz Journal of the American Chemical Society 135 (13), 4970-4973, 2013 | 128 | 2013 |